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Immune system articles from across Nature Portfolio

The immune system is a complex network of cells, tissues and organs that work together to protect the body from harmful substances and organisms and defend against disease. The immune system can be classified into distinct responses, such as innate immunity and adaptive immunity, or humoral immunity and cell-mediated immunity.

Related Subjects

  • Dendritic cells
  • Monocytes and macrophages

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immune system research paper

Bundle structures inside the deep cervical lymphatic vessels of mice

  • Joonyoung Shin
  • Sungchul Kim

immune system research paper

Advanced three-dimensional X-ray imaging unravels structural development of the human thymus compartments

Savvidis et al. present x-ray 3D imaging visualizing the internal anatomy of the human thymus across developmental stages. Quantification and evolution of Hassall’s bodies and medulla-to-cortex ratio, indicate they should be considered a third compartment of the thymic anatomy.

  • Savvas Savvidis
  • Roberta Ragazzini
  • Alessandro Olivo

immune system research paper

Inhaled particulate accumulation with age impairs immune function and architecture in human lung lymph nodes

Carbon-containing particulates accumulate with age in a subset of macrophages in human lung-associated lymph nodes, decrease macrophage phagocytic capacity and turnover and disrupt lymphoid tissue structure, potentially compromising adaptive immune responses.

  • Basak B. Ural
  • Daniel P. Caron
  • Donna L. Farber

immune system research paper

Asplenia and spleen hypofunction

Asplenia and hyposplenism can have multiple and complex causes and lead to morbidity and mortality, especially owing to overwhelming post-splenectomy infections. In this Primer, Lenti and colleagues review epidemiology, pathophysiology, diagnosis and management of these conditions, and discuss patient quality of life and future strategies.

  • Marco Vincenzo Lenti
  • Antonio Di Sabatino

immune system research paper

The human splenic microcirculation is entirely open as shown by 3D models in virtual reality

  • Birte S. Steiniger
  • Henriette Pfeffer
  • Oleg Lobachev

immune system research paper

Ascorbate maintains a low plasma oxygen level

  • Louise Injarabian
  • Marc Scherlinger
  • Benoit S. Marteyn

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immune system research paper

Immune aging impairs tumor control

  • Hannah Walters

Sex differences are skin deep

  • Stephanie Houston

immune system research paper

Rebalancing the aged immune system

A t reg cell duo for vat control.

  • Maria Papatriantafyllou

Eosinophils regulate bone remodelling

Results of a new study indicate that eosinophils have a role in maintaining bone homeostasis through their inhibitory effects on bone-resorbing osteoclasts.

  • Sarah Onuora

Remembering T reg cells

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immune system research paper

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