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Thesis Nootropics Review

Thesis has a range of targeted nootropics you can combine to optimize your results. our team will help you decide which ones are right for you..

Daniel is a senior editor and writer at Innerbody Research. After receiving his bachelor’s degree in writing, he attended post-graduate studies at George Mason University and pursued a career in nutritional science.

Dr. Segar is a cardiology fellow at the Texas Heart Institute and a member of Innerbody Research's Medical Review Board.

In this Review

Nootropics in general offer the potential to improve cognitive abilities and regulate mood without the need for a prescription. And while more research is necessary, current data suggests that they consist of ingredients that are generally safe and effective for healthy adults. 35 However, Thesis isn’t the only provider of high-quality nootropics, nor do they offer especially low prices. In this review, we'll compare and contrast Thesis’ six formulas and see how they stack up against a growing field of competitors.

Our Findings

• You can feel most results within an hour
• Products are third-party-tested for purity
• All options available without stimulants
• Outstanding phone support
• Subscriptions include complimentary wellness coaching
• Free shipping on all orders
• Use code INNERBODY for 10% off your first order
• Somewhat more expensive than competitors
• Up to four large pills per dose

Despite the somewhat high price, we recommend Thesis to anyone looking for a nootropic subscription that can be tailored to their specific needs. The formulas from Thesis provide tangible benefits with minimal ingredients, and each formula is available with or without caffeine. Thesis also offers stellar customer service and delivers their product in individually packed doses you can take just about anywhere.

Special Offer: Take 10% OFF with code INNERBODY

Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. As nootropics have become more important players in the supplements landscape, we’ve taken a serious look at the key players to see which ones are worthwhile.

Thesis exists in a class of nootropics that combines multiple nootropic ingredients to achieve specific goals. We’ve spent hundreds of hours researching and testing various nootropics, including both individual ingredients and combinations like Thesis offers. In researching Thesis and their competitors, our team has read more than 100 clinical studies examining the efficacy and safety of nootropic ingredients, and we’ve combined all of that knowledge with our experiences to create this review.

If you're curious about our team's experience using Thesis nootropics and wondering how the products will arrive at your door, we made this handy, 5-minute video summarizing those details:

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

How we evaluated Thesis

To evaluate Thesis, we examined the extensive research available on each ingredient the company uses and compared them to a growing marketplace of nootropics, many of which our testing team has tried over the past few years. Specifically, we assessed how effectively Thesis' formulas work, as well as their safety, cost, and the convenience of acquiring and taking them.

Ultimately, we found Thesis to be one of the more reliable companies in terms of product quality and customer care, even if they are among the more expensive nootropic brands. For any nootropic, you’re looking to create a noticeable effect in brain performance, and altering anything to do with that sensitive chemistry likely warrants a fair investment. The bargain bin is not typically where you want to shop for mind-enhancing substances.

We’ll get into a more direct comparison between Thesis and their competitors a little later, and you’ll see that the balance between their price and overall value is quite reasonable. For now, let’s look at each criterion in more detail.

Effectiveness

Nootropic companies have a plethora of ingredients at their fingertips when they formulate their products. Some companies take a modern approach, focusing on the latest research into established Western medicines. Others look to the past, where ancient Chinese and Ayurvedic practices employed various botanicals to achieve cognitive effects. The best companies combine these approaches, using potentially beneficial ingredients that science supports.

Thesis takes this combined approach, employing just under three dozen ingredients from amino acids to ancient herbs across their six products. The company scores highly in effectiveness thanks to the ingredients they choose and the doses they offer for each, making it likely that you can notice their combined effects.

Individual results will vary due to everything from sleep patterns to diet, but most people should find benefits in at least one of Thesis' six formulas. Caffeinated formulas generally have more pronounced effects than stimulant-free versions, but the value of Thesis offering every formula with or without stimulants cannot be overstated.

One minor knock against Thesis is that, unlike some of their competitors, Thesis does not have a nootropic blend designed for improved sleep. Better sleep supports cognition and mood, so some companies offer formulas designed specifically for sleep promotion with ingredients like melatonin. That said, some of Thesis’ formulas contain lion’s mane or Zembrin (a branded form of Sceletium tortuosum that’s been shown to reduce anxiety and promote sleep). 2 3 And the amount of Zembrin used in Thesis’ Creativity and Confidence blends is the exact same amount used in these successful studies — 25mg.

Good nootropics are, unfortunately, a bit expensive. You can find less expensive options than Thesis, but their $79 monthly rate is right in the middle of what the market demands. You could also argue that the ingredient quality, customization options, and overall efficacy Thesis offers make it a superior value to many less expensive alternatives. Still, the price remains a sticking point for some.

Let's compare the monthly and per-dose costs with some of Thesis' closest competition. The prices below reflect subscription savings where available.

Three of the seven competitors included in the chart above are more expensive than Thesis, and another three are no more than $15 less expensive, revealing their generally average cost. Focus Factor — consistently our top budget pick among nootropics — costs much less than others in the field and includes many ingredients with associated clinical research. The downside is that increasing the number of ingredients (even when they seem to work) increases the odds of an adverse reaction.

TruBrain is the only company that truly compares to Thesis from a quality and variety standpoint. Other companies offer only one or two formulas, whereas Thesis and TruBrain each offer several more targeted products. TruBrain allows you to spend just $69 on your first jar when you subscribe — $10 less than Thesis — but that price shoots up to $119 every month after that, making Thesis the superior value.

When we consider the safety of any supplement, we look at available research into individual ingredients and compare those dosages with what the supplement offers. Whenever possible, we also test the product ourselves to observe its effects on us. Additionally, we look for safety standards in manufacturing that can provide added peace of mind, like third-party testing and compliance with the FDA’s Good Manufacturing Practices (GMP).

Thesis manufactures their products in GMP-compliant facilities and has third-party testing performed to assess the purity of each ingredient and formula. And the clinical research involving the lion's share of their ingredients reveals minimal risk profiles with few to no adverse effects reported. That said, ashwagandha isn’t safe for pregnant or breastfeeding individuals, and it can stimulate thyroid activity, so anyone with thyroid concerns (hyper- or hypothyroidism) or on medication to regulate thyroid function should be careful. 36 37

Thesis also limits their formulas to a handful of ingredients, which reduces the likelihood that any one of them would cause an adverse reaction. This is pretty typical of nootropics in Thesis’ class, but less expensive nootropics might try to convince you of their value by stuffing a single blend with several dozen components. That might increase the chances you feel some positive effect, but the side effect risk goes up by the same token.

Convenience

Our convenience rating considers various aspects of a user's experience. It usually starts with the quality of a product's website design and whether or not its pages are easy to navigate. We also consider the presence of subscription systems that make reordering easier and money-back guarantees that protect your investment. A company's customer service is another vital aspect of convenience, especially if you need questions answered. The quality of an FAQ section, the availability of representatives via chat or phone call, and the responsiveness to email inquiries all play a part here.

Our convenience rating is also informed by the steps required to actually take the product. Nootropics often consist of large capsules, and doses can contain anywhere from 1-7 capsules, which is awful for anyone with difficulty taking pills. Smaller capsules, fewer capsules per dose, and simple dosing schedules are ideal. Thesis’ capsule count varies per formula, ranging from 2-4 mid-size capsules you can take 30 minutes before you might want or need their effects.

To summarize some important aspects of nootropic company convenience, let's look at which companies have large capsule counts, good money-back guarantees, and subscription systems.

Thesis also provides a service that few other companies offer: free consultations with in-house nootropic coaches. These experts can help you figure out the best time to take specific Thesis formulas and guide your experience so you can tell whether or not they're working for you. Follow-up consultations are also free as long as you subscribe to the product.

What are nootropics?

Nootropic is a term most people use to refer to any non-prescription supplement that can boost brainpower. 4 The technical definition is a little more nuanced — encompassing prescription medications like Ritalin and Adderall — but the supplement industry has largely co-opted it to categorize the new class of non-prescription products. The word loosely translates from its Greek origins to mean mind-changing, and the majority of ingredients in a given nootropic seek to alter the brain’s cognitive abilities, as well as its governance of mood and energy.

Most nootropic supplements contain botanical ingredients, vitamins, minerals, and amino acids that boast at least some clinical research connecting them with improvements in any of the following:

Compared to their prescription cousins, nootropic supplements aren't particularly strong. Still, limited clinical research indicates a tangible benefit to taking them.

What is Thesis?

Thesis is a supplement company with a focus on nootropics. Their founders each had experiences growing up with what would today be considered learning disabilities, and they credit nootropics for changing their lives. They make six distinct nootropic formulas, each with a specific ingredient profile.

Thesis differentiates themselves from their competitors in several critical ways:

• They offer a starter kit containing a personalized combination of four blends.
• You have the option to remove caffeine by request from any formula.
• They provide some of the best phone support we've ever experienced.
• Their targeted formulas conform to changing needs.

By providing you with a mix of formulas, Thesis gives you the ability to enhance the aspects of your cognitive and emotional life that need it the most on any given day. Maybe you know you have low energy levels on Mondays and Wednesdays, so you can take the Energy formula on those days. Maybe you want to devote your weekends to artistic pursuits. You can use the Creativity blend for that. Or you might find that one of their six blends works well for you in any situation. In that case, you can adjust your order to receive only that formula.

Thesis' customer service — particularly over the phone — is outstanding. While many customers might find chat support more convenient, our testers rarely waited more than a minute to speak to someone, and Thesis employs phone operators who are extraordinarily knowledgeable about the product and nootropics in general. Their email support is fine, and their chat support often redirects to an email inquiry. But that phone support is some of the best our testing team has experienced.

Is Thesis safe?

Most of the ingredients that Thesis uses in their nootropics exhibit minimal side effects in clinical research, so there’s a good chance that Thesis' various formulas will be safe for most people. But Thesis has nearly three dozen ingredients in their catalog, and not all of them will be safe for all users, including those who are pregnant or breastfeeding. Of course, the most important thing you can do is talk to your doctor before taking Thesis.

The most common side effects to watch out for when you start taking Thesis nootropics include:

• Loss of appetite
• Digestive issues

Thesis advises discontinuing their nootropics if you experience persistent headaches or an upset stomach.

Some Thesis products may present contraindications with certain prescription medicines. For example, ashwagandha has been shown to normalize thyroid hormone levels in people with hypothyroidism. 5 This has led some to believe that it could conversely cause thyrotoxicity in people with hyperthyroidism, though it’s worth noting that the study in question employed double the highest ashwagandha dose you’ll find in Thesis nootropics — the study used 600mg, and the ashwagandha dose in Thesis’ Creativity is 300mg.

Still, this should make abundantly clear the case for speaking with your doctor prior to taking Thesis. This is especially true considering the lack of research into the specific ingredient combinations you’ll find in Thesis products. There is also very little research looking into the risks of combining nootropic supplements with prescription stimulants such as Ritalin, Adderall, or Vyvanse.

Some side effects, such as jitteriness, can be attributed to the caffeine in Thesis formulas. The fact that you can elect to remove caffeine from any formula expands the company’s reach to anyone with caffeine sensitivities and those who really don’t want to give up their morning cup of coffee. If you want caffeine in your Thesis formula, we recommend trying it without having had any coffee first, so you can see how it affects you.

Insider Tip: If you’re not sure whether to get your formula with or without caffeine, we recommend getting it with caffeine. Thesis isolates the included caffeine in a single capsule separate from other ingredients. Caffeinated formulas cost the same as uncaffeinated ones, and you can always elect not to take the caffeine capsule (the smallest capsule in any formula, containing a white powder).

What are the ingredients in Thesis?

Thesis uses an impressive set of ingredients, many of which have been part of respectable clinical research. Not all of the effects they hope these ingredients provide have been proven with sufficient statistical significance or over multiple studies in different populations, but what we do know strongly suggests efficacy.

Here's a look at several Thesis ingredients that have encouraging research behind them:

Several studies on mice show that dihydrohonokiol-B (DHH-B) has potent anxiolytic effects. 6 That means it may be able to help combat anxiety. However, we can’t say this for sure since there haven’t been any studies conducted on humans yet, so any potential benefits are speculative at this time. 25 Converting the successful dose used in mice (1mg) to the equivalent human amount (4.86 mg) is about half the amount used in Thesis’ Confidence (10mg). 6

In numerous studies, ashwagandha has been shown to reduce stress and anxiety. 32 Thesis uses a branded KSM-66 ashwagandha, which has a high standardized count of withanolides — the component of ashwagandha responsible for its positive effects. 33 This ensures both efficacy and consistency from doses that align with those used in successful studies.

While every formula is different, you'll notice that each contains caffeine and L-theanine. The nootropic properties of caffeine are well established. 19 L-theanine — a non-stimulant derived from green tea — has been shown to smooth out the jittery effects of caffeine. You can easily have caffeine removed from any Thesis formula for no extra cost, which is unique in the nootropic market. The L-theanine will remain, as it has its own set of cognitive benefits in addition to its ability to tame caffeine. 20

Saffron offers multiple benefits, including increased levels of dopamine and glutamate, that are dose-dependent. Human studies have also shown positive effects on depression symptoms. Thesis’ Confidence uses 28mg, which is 2mg less than what was used in many of the studies on saffron’s antidepressant effects. However, one study did find success with as little as 15mg. 7

A review of more than 120 scientific articles looking into the cognitive effects of phosphatidylserine concluded that it “safely slows, halts, or reverses biochemical alterations and structural deterioration in nerve cells.” The study goes on to say that it “supports human cognitive functions, including the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories, the ability to retrieve memories, the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate.” 34

Derived from a South African plant, Zembrin appears to provide cognitive and anti-anxiety effects as demonstrated in clinical studies on human participants that used the same 25mg dose found in Thesis Creativity and Confidence. 8

Synapsa is a patented form of Bacopa extract, a traditional Ayurvedic memory enhancer. Studies on humans resulted in statistically significant improvements in cognitive tests. The study used 150mg twice daily (300mg total), which is only 20mg less than the 320mg used in Thesis’ Logic. 9

7,8 DHF is a small molecular TrkB agonist that can easily cross the blood-brain barrier. It can increase brain-derived neurotrophic factor (BDNF), a protein that improves neuroplasticity, learning, and memory. BDNF deficiencies are connected to numerous cognitive ailments as well. However, no human studies have been conducted. 26 In mice, 7,8 DHF appears to enhance spatial memory. When converting the effective dose for mice to humans, Thesis’ Clarity offers roughly 6mg more (about 24mg compared to Thesis’ 30mg). 27

Choline is a precursor to acetylcholine, a powerful neurotransmitter in the peripheral, autonomic, and enteric nervous systems. 10 One study on older adult human participants found that taking 187-399mg per day of choline reduced the risk of low cognitive functioning by nearly 50% compared to an intake under 187mg per day. 28 The CDP choline content in Thesis’ Energy is 300mg.

A 2010 clinical study on 485 older adult (over 55 years old) subjects found that 900mg per day of DHA improved memory and learning in those with age-related cognitive decline. 11 And another study in healthy adults 18-90 years old found that 580mg per day helped improve memory. 29 Unfortunately, the amounts used in many studies to improve cognitive function are quite a bit more than the 200mg (which is DHA and L-lysine combined) found in Thesis’ Logic.

Like choline, Alpha-GPC acts as an effective acetylcholine precursor. Studies also show that supplementation with Alpha-GPC can stave off exercise-induced reductions in choline levels. The effective amount used in the mentioned study is 200mg, which is less than half of what you’ll find in Thesis’ Clarity (500mg). 12

In addition to being an effective treatment for neuropathic pain, agmatine appears to have potent effects as an antidepressant. A five-year safety case report study concluded that there are no long-term side effect risks. Thesis’ Creativity only contains 250mg, which is well below the amount tolerated by study participants (2.67g per day). 13

Research into epicatechin indicates that it can enhance cerebral blood flow, delivering more oxygen to the brain to ensure it operates at its highest efficiency. The most effective dose for cognitive benefits appears to be over 50mg per day, and Thesis’ Clarity contains 278mg. 14

Lion's mane has been shown to increase nerve growth factor and promote neurite outgrowth of specific neural cells. It's a safe and reliable neurotrophic, but studies have debunked claims of neuroprotective properties. 15 A very small study of only 41 participants found that 1.8g of Lion’s mane may reduce stress and improve cognitive performance. 30 Thesis’ Clarity contains 500mg of Lion’s mane.

Hyperphenylalaninemia, a severe deficiency in phenylalanine, results in reduced dopamine, serotonin, and noradrenaline levels in the brain. 16 It can also alter cerebral myelin and protein synthesis. Supplementing with phenylalanine may provide neuroprotective benefits.

In a 2020 study, phenylalanine was a large component in a mix of seven amino acids that appeared to improve cognitive, psychological, and social functioning in middle-aged and older adults. Effective doses ranged from 0.85g to 1.7g of phenylalanine. A serving of Thesis’ Motivation contains 500mg, a bit under half of the average amount. 31

Examining the six formulas

Thesis has six nootropic formulas in their lineup (even though you can only choose up to four of them per box). Several other nootropic companies like TruBrain and BrainMD boast targeted lineups, as well, but Thesis is the Goldilocks of the bunch. Where BrainMD’s hyper-specific formulas rely on perhaps too few ingredients to make them worthwhile, many of TruBrain’s complex blends lack real specificity. With Thesis, you get targeted effects from numerous ingredients in moderately complex and reasonably priced combinations.

Each Thesis formula has a blend of ingredients that addresses specific needs. Their names give you a pretty big clue as to what the company intends each to do, but a closer look at their ingredients will help you understand how they achieve this.

Their formulas are:

Interestingly, the company thinks of its formulas as working well in pairs. You don't have to utilize them as such, but it's helpful to know how they view their most effective combinations. The following list details their purported combined benefits.

Enhances focus, eliminates brain fog, and lets thoughts flow naturally

Gets you going, keeps you going, and never crashes

Sparks new ideas, inspires extroversion, and revels in openness

You'll usually only take one formula at a time, but these pairs may act synergistically for specific personality types or cognitive needs.

Note that your first shipment of Thesis will contain six individually packed doses for four of these six formulas. Thesis chooses these formulas for you based on the results of an intake questionnaire, but you can make adjustments to that shipment on the customer dashboard before the shipment leaves their warehouse.

Let's take a closer look at each formula as they would appear with caffeine included.

Thesis Clarity

Thesis Clarity relies on 7,8 DHF (dihydroxyflavone), Alpha GPC (glycerylphosphorylcholine), epicatechin, and lion's mane to increase blood flow to the brain and stimulate the production of acetylcholine, a powerful neurotransmitter associated with learning, memory, and attention. It's particularly adept at cutting through brain fog.

Here's a look at Clarity's full ingredients list:

• Alpha GPC: 500mg
• Lion's Mane Mushroom: 500mg
• Camellia sinensis tea leaf: 278mg
• Dihydroxyflavone: 30mg
• Caffeine: 100mg
• L-Theanine: 200mg

One dose of Clarity consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Logic

Thesis Logic contains triacetyluridine (TAU), which caters to the health of the entire central nervous system. It also uses phosphatidylserine to help facilitate communication between and protection of brain cells. 17

This is Logic’s complete ingredients list:

• Ginkgo Biloba: 160mg
• Theobromine: 100mg
• Phosphatidylserine: 400mg
• High DHA Algae: 200mg
• Triacetyluridine: 30mg
• Bacopa Monnieri: 320mg

One dose of Logic consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Energy

Thesis Energy uses cysteine and tyrosine alongside caffeine to deliver a steady energy supply. It also includes TeaCrine, a branded form of theacrine, which partners with caffeine to affect adenosine signaling and prevent fatigue.

Here’s a full list of Energy’s ingredients:

• Citicoline: 300mg
• Mango leaf: 300mg
• Theacrine: 100mg
• N-Acetyl cysteine: 500mg
• Indian trumpet tree: 100mg
• N-Acetyl L-tyrosine: 300mg

One dose of Energy consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Motivation

Blood flow and cellular function are at the core of Thesis Motivation . It employs artichoke extract, forskolin, and B12 to achieve these goals, with a healthy dose of phenylalanine for added focus and motivation.

Here's Motivation's full ingredients list:

• L-Phenylalanine: 500mg
• Methylliberine: 100mg
• Vitamin B12: 1000mcg
• Forskolin: 250mg
• Artichoke: 450mg

One dose of Motivation consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Creativity

Thesis Creativity aims to realign you with your inspiration by removing barriers caused by stress, anxiety, and depression. It contains ingredients with powerful anxiolytic properties and 5-HT reuptake inhibition.

Here's a look at Creativity’s ingredients list:

• Alpha GPC: 150mg
• Agmatine sulfate: 250mg
• Panax ginseng: 200mg
• Ashwagandha root: 300mg
• Sceletium tortuosum : 25mg

One dose of Creativity consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Confidence

Confidence is designed to work hand-in-hand with Creativity, using saffron and DHH-B from magnolia bark to increase dopamine levels and decrease anxiety. One fascinating ingredient in this formula is sage extract, which one 2021 study showed can help with various memory tasks, including name and face recognition. 18 It’s worth noting, though, that this study employed a 600mg dose compared to Thesis’ 333mg dose.

Here is Confidence's complete ingredients list:

• Saffron: 28mg
• Magnesium bisglycinate: 500mg
• Sage: 333mg
• Magnolia Bark: 10mg
• Ashwagandha leaf & root: 120mg

One dose of Confidence consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Our Thesis testing results

Our testing team has tried every Thesis formula (with and without caffeine) to determine their short- and long-term efficacy, at least at an anecdotal level. Here’s a quick summary of our experiences:

Clarity provided our testers with a combined sense of focus and mental ease, though we mostly found that it worked best from its second day forward. The very first dose is mildly effective, but it served us better as a loading dose. We had no crash from either caffeinated or uncaffeinated formulas.

Our testers found that Logic provided a similar experience as Clarity, increasing focus and mental acuity, but the caffeinated formula caused a crash in two of our testers. By excluding the caffeine, that crash can be avoided, though that comes at the expense of some efficacy.

We were very curious about how this formula would perform without the caffeine. Our testers had a noticeable increase in energy without jitteriness about one hour after taking Energy. The caffeinated version caused the worst crash of all the formulas, but we were pleased to find that the formula without caffeine still provided noticeable energy increases without a crash.

Our testers are generally a pretty motivated bunch, so we might not have been the best group to evaluate this particular formula. The testers who felt an uptick in a sense of motivation described it more like a feeling of being able to follow through on tasks with less distraction and completion anxiety.

Creativity, like Clarity, seemed to work better for our testers on its second and third days than on its first. Testers generally described a sensation similar to Motivation but without the feeling of being “on rails,” as one tester put it. It seems to allow for more curiosity and exploration, though not necessarily as much follow-through.

This is Thesis’ newest formula, so fewer of our testers have tried it. Among those who have, one tester with a mild case of social anxiety described feeling a bit more relaxed among groups of people. Testers preferred this formula without caffeine.

Thesis pricing, shipping, and returns

Thesis keeps their price structure decidedly simple. This is refreshing, considering the range of nootropics they offer. You don't have to worry about one formula costing you more than another. However, Thesis doesn't make a non-subscription approach economically feasible.

Every Thesis shipment — including the starter pack — consists of four small boxes, each containing six doses of a single formula. That’s 24 doses/month.

Here's how it works:

• Any one-time purchase of a one-month supply, including the starter kit, costs $119.
• When you subscribe, that monthly cost is only $79.
• You can take an extra 10% off your first order with the coupon code INNERBODY

Subscriptions require an account with Thesis, which gives you access to a well-designed customer dashboard. This is where you can easily make formula adjustments, alter your shipping schedule, or cancel your subscription entirely.

Shipping from Thesis is free in the U.S., and the company offers a 30-day money-back guarantee. In our testing experience, we attempted a return on a second shipment into the subscription. While it isn’t the company’s policy to do so, they refunded our money and let us keep the product. This is similar to some other “Keep it” guarantees we’ve seen from competitors, and we appreciated it.

Getting started with Thesis Nootropics

Thesis' website is easy to navigate, but it is inconvenient that you must complete the signup questionnaire before accessing formula-specific pages. There are ways around this — like direct searching or just knowing the formula URLs — but we think reviewing formulas should be a little easier when you first get to the site. And you won’t be able to place an order for anything until you complete the questionnaire.

The user interface for managing your subscription is exceptionally intuitive. You can quickly adjust your formula combinations, specifying whether or not you want specific formulas to contain caffeine.

Setting up a subscription with Thesis is a straightforward process. Here are the basic steps:

• Take the Thesis quiz . This will create a starter kit specific to your results. (You can also build a box from scratch if you know which formulas you want to try.)
• Order your starter kit. We recommend going with the kit Thesis creates after your quiz, but if you change your mind, you can use the customer portal after placing your order to make any changes to the formula combination before it ships.
• Set up a coaching consultation. This is an optional step, but we recommend it and encourage you to have your first consultation before your kit arrives.
• Take your nootropics as needed. Most people can experience some of Thesis nootropics' benefits within a few hours of ingestion. Some ingredients and formulas may take a few days to produce results.
• Refine your order. As you near the end of your first month, you can head over to the Thesis website and customize your next order to include the formula or formulas you like most.
• Set up follow-up consultations as needed. These will help you refine your future orders and maximize your results.

When you subscribe to the starter kit, you will continue receiving that kit every month until you customize your order. Thesis divides their boxes into four six-dose supplies, and you can mix and match those supplies to suit your needs. For example, you could boost energy on the weekdays and creativity on the weekends by getting a one-month supply with 18 servings of Energy in three packages and six servings of Creativity in a single package.

Personalized insights and coaching

When you take the quiz on the Thesis website, you'll get personalized insights comparing your results to other quiz-takers and a data set developed from nearly 500 scientific studies. The parameters in your results cover don’t completely line up with their formulas, but they include:

These results inform the system to make recommendations for your starter kit. After you order, you can set up a consultation with a Thesis coach. These consultations are free, and you can have as many follow-up sessions as you like. Other companies have apps or online resources like blogs or courses to help you on your nootropic journey, but Thesis’ personalized coaching offers a unique approach and execution.

Consultation calls last around 15 minutes, though some of our testers had their sessions go longer as their coaches' schedules allowed. We received best practices information about taking nootropics that covered dose timing, formula application, and more. Some of our testers also received diet and exercise advice that coincided with their formulas.

Alternatives to Thesis

There are generally two tiers of products in the nootropics landscape. The lower tier consists of products that cost between $20 and $40. Many of these nootropics contain proprietary blends that obscure the exact quantities of ingredients, presumably so companies can use more of the least expensive components. Some companies in this tier disclose their ingredient quantities but may not source them from the highest quality suppliers or perform third-party testing of any kind.

Top brands in this tier include:

• Onnit Alpha BRAIN
• Moon Juice Brain Dust
• Focus Factor

The second tier — where you'll find Thesis — consists of more expensive nootropics that spell their contents out clearly, use high-quality ingredients, and often perform third-party testing to ensure safety and potency. Top brands in this tier include:

• Qualia Mind

Hunter Focus

We have a comprehensive breakdown of our top nootropics , but here's a concise breakdown of Thesis' most comparable competition.

TruBrain offers one of the widest varieties of nootropics of any company — one of the few catalogs that rivals the variety Thesis offers. They also have some novel and beneficial delivery methods for their nootropic ingredients. Those include energy bars and liquid shots that are outstanding for anyone with difficulty swallowing pills.

TruBrain offers their nootropics in a targeted fashion, not unlike what you get from Thesis. They formerly offered their targeted blends in shot form only, but now you can get any of these targeted blends in capsule or liquid shot form. The shots come in small 1oz pouches that make them easy to take anywhere.

TruBrain's targeted blends include:

This is TruBrain's original blend. It contains seven nootropics, including Noopept, a branded form of N-phenylacetyl-L-prolylglycine ethyl ester. This blend is caffeine-free.

The Strong blend is identical to the Medium formulation in contents and doses, but it also contains 100mg of caffeine.

The Extra Strong formula builds on the Strong blend by adding 150mg of adrafinil (2-(diphenylmethyl)sulfinyl-N-hydroxyacetamide). 21 This wakefulness-promoting substance may also help with weight loss and athletic performance.

TruBrain's Sleep formula contains just four nootropic ingredients: GABA, melatonin, 5-HTP, and a blend that TruBrain calls "functional oils."

Mellow is identical to the medium strength formula, but it adds the functional oil combination used in Sleep.

This formula contains Lion's mane, a mushroom that may promote neural growth , though human studies are necessary to determine if this is true. 22 Its other nootropic ingredients are rhodiola, guayusa, and rosehips.

A 30-day supply of TruBrain nootropic shots costs $89. That's $10 more than the subscription cost for a one-month supply of Thesis. Some of their shots contain caffeine, and others don't. If it already contains caffeine, there's no way to alter a TruBrain formula to be stimulant-free.

The first month of TruBrain capsules costs a bit less, coming in at $69. After your first month, however, the price goes up to $119. That makes Thesis the better value, but if you want the best possible nootropics for sleep support, it might be worth the extra money to check out TruBrain.

Qualia Mind is a brand under the Neurohacker Collective, a company that offers several products to address things like sleep quality, skin health, and vision. They have three nootropics available:

• Qualia Mind Caffeine-Free
• Qualia Mind Focus

Their original blend is comprehensive, consisting of nearly 30 ingredients in high doses. That means it's liable to provide you with noticeable effects. It also means you might not know which of those effects are coming from which ingredients, and some of the less beneficial components in your body may also have side effects you'd rather avoid.

The caffeine-free version is identical to the original formula but leaves the caffeine out. Qualia Focus is a more streamlined offering with only seven nootropic ingredients, including caffeine, L-theanine, and L-ornithine. 23

Initial shipments from Qualia Mind are significantly discounted, but after the first month, the price makes theirs one of the most expensive nootropics we've tested. For example, the first month of a subscription to Qualia Mind costs just $39. After that, it costs $139/month. And a one-time purchase is $159.

One inconvenient aspect of Qualia Mind is that a single dose consists of seven capsules, which can get tiresome even for people who don't have trouble swallowing pills. On the bright side, Qualia's 100-day money-back guarantee allows you to try it for a little over three months to determine if you can handle that kind of daily dosing.

Hunter Focus is one of three supplements in the Hunter stack alongside the company's Test and Burn supplements. The stack is intended for male use — Test is a testosterone supplement — but Focus and Burn are suitable for men and women.

Like Qualia Mind, Focus has a long list of ingredients in generous doses. In fact, one serving of Hunter Focus is like taking all six of Thesis' formulas at once. That said, the serving itself is difficult to swallow, as it consists of six large pills.

Another knock on Hunter is that they don't offer a subscription system. That means you can't get an extra discount, and you must remember to reorder when you're running low (theoretically, a nootropic like this should boost your memory). There's also no money-back guarantee to speak of, only a return policy with a relatively short window that only applies to unopened products.

One bottle of Hunter Focus costs $90, and shipping is $8.95 unless you buy more than one bottle at a time. The company will throw a fourth in for free if you buy three bottles at once. That's the only way to get any savings through Hunter.

Individual nootropic components

Many companies offer combinations of nootropic ingredients to perform specific brain-related tasks or even provide globally positive cognitive benefits. However, the scientific research behind most of these ingredients almost always includes just one rather than a combination. Some people prefer to try one at a time to minimize the potential for side effects and determine if one particular ingredient works for them. A few companies offer single-ingredient nootropic supplements for this specific purpose.

Our favorite company dealing in individual nootropic components is Nootropics Depot. They offer a wide variety of single-ingredient supplements and a few targeted blends. The prices are generally fair, with an average range running from $16-$70. A 30-day money-back guarantee covers every purchase, and you get free shipping on orders over $50.

Nootropics FAQ

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Specific nootropics affect different parts of the brain in their own ways. Some — like caffeine — reduce fatigue by blocking adenosine receptors, while others act to protect neural connections that are already present while possibly contributing to new neural growth. 24 Some also mitigate depression and anxiety, which frees up the brain to perform at its best.

Are nootropics safe?

The safety of a nootropic depends on the specific ingredients involved. Many are perfectly safe in the doses commonly employed by nootropic companies, but some can cause reactions like increased heart rate, gastrointestinal discomfort, headache, and even tremors. The smartest thing to do is to talk to your doctor before introducing any new supplement to your regimen.

Do nootropics really work?

Many nootropic supplements are noticeably effective — caffeine is a great example. Efficacy varies depending on the specific component or combination. Fortunately, a lot of companies offer money-back guarantees, so you can try their products to see if they work for you without much financial risk.

Will nootropics make me smarter?

Nootropics won't necessarily make you smarter, but many can increase your alertness, improve short-term recall, and promote neural growth and protection. That creates a great environment for learning if you apply yourself while using nootropics, and many ingredients can help you with the motivation it takes to do so.

How do you pronounce nootropics?

The 'noo' in nootropics comes from the Greek nous , which philosophers use to mean mind or intelligence. The 'tropic' in nootropic comes from the Greek tropikos , which relates to turning or changing. So, nootropic roughly translates to mind-changing. You pronounce the 'noo' like 'new' and the 'tropic' with a long O sound, like 'toe pick.'

Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

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Ashe, K., Kelso, W., Farrand, S., Panetta, J., Fazio, T., De Jong, G., & Walterfang, M. (2019). Psychiatric and Cognitive Aspects of Phenylketonuria: The Limitations of Diet and Promise of New Treatments . Frontiers in Psychiatry, 10 , 434708.

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What Is Thesis?

How does it work, thesis nootropics benefits, thesis blend breakdown, thesis energy benefits, clarity benefits, motivation benefits, logic benefits, creativity benefits, side effects, who should take it, who shouldn't take it, where can you buy it, other user reviews, how does thesis compare to other supplements, our verdict on thesis nootropics.

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Thesis Nootropics Review (2024) Is It Worth The Hype?

As a fitness coach, I've seen the impact of high-quality nootropic supplements on motivation and concentration during workouts.

Teaming up with my dietitian and 12 clients, we documented the significant cognitive benefits and general effects of Thesis over a period of four weeks.

Does it genuinely fulfill its promise of enhancing your mental performance and focus?

Before trying out the supplement, keep reading and find out if it's right for your mental wellness needs.

Ingredients

Who is it for?

• Individuals seeking personalized nootropic supplements to enhance cognitive performance, energy, and focus.
• People looking for a tailored approach to mental wellness and cognitive enhancement.

Who is it not for?

• Those looking for a cost-effective solution or who prefer a one-size-fits-all supplement.
• Individuals sensitive to caffeine or those who prefer supplements without multiple ingredients.

Final Verdict

Thesis Nootropics offers a personalized approach to cognitive enhancement with a variety of blends tailored to individual needs. Its high-quality ingredients and positive user ratings make it a viable option for those looking to improve mental performance, though the cost and complexity of the blends may not suit everyone.

Thesis is a stack of supplements that aims to improve cognitive function, mental stamina, mood, and overall mental energy levels.

Thesis nootropics' energy formula claims to boost energy levels while catering to individuals following a certified gluten-free diet, promoting positive habits and supporting nerve health.

What's particularly interesting about purchasing this stack is the Thesis algorithm.

It’s a set of questions that assess your personal needs to create a bespoke starter kit.

More on this shortly.

As a result, you get a recommendation from a couple of their products to provide personalized blends for nootropics.

Let’s learn more about how Thesis supplements work with your brain health.

Thesis Nootropics

Rated With Total Shape's Scoring System

The Thesis experience begins with a questionnaire to assess your needs and goals, like improved physical and mental energy.

Based on your responses, the algorithm will recommend different Thesis blends to help you achieve your goals.

After going through the quiz, you get a recommended Thesis starter kit.

The five different products Thesis then recommends claim to work similarly to smart drugs by boosting your cognitive function and mood.

But unlike prescription medications, Thesis uses natural ingredients like vitamins, amino acids, minerals, and herbs.

“Nootropics, a greek word meaning 'Towards the Mind', are compounds that are both (1) neurologically active and (2) directly or indirectly enhance cognitive potential via increased capabilities (ie. reflexes), state of well-being, or learning potential.” - Kamal Patel, MPH, MBA at Examine.com

Once you are a Thesis customer, you can also set up a meeting with a Thesis coach to review your stack and the effects you are looking for and experiencing.

But does that make Thesis legit?

Let’s see what our detailed clinical research reveals.

The first thing that we got our testing team to do is to go through a full week of keeping an hourly journal to self-evaluate their mood, concentration, and cognitive function.

Then we put them through three weeks of taking their Thesis recommended stack and got them all to keep their hourly journaling going.

The first thing we noted was that the energy blend and creativity formula seemed to give our clients a good boost in brain performance.

And the folks that took the motivation blend a few hours before heading to the gym also found they were more focused on their workouts.

However, the majority of our test group highlighted that the effects seemed to wear off after about 4–5 hours.

We also noted that the logic formula didn’t provide a huge benefit, which could be down to a lack of a proven formula.

We also found that the Thesis nootropics cost can mount up if you want to stack a few of them.

• Allows you to combine different product formulas for personal goals
• Provides support from coaches to help you refine your stack
• Positive impacts on mood and concentration levels
• Some of the ingredients are not supported by reliable clinical trials
• You may need to swallow quite a few capsules, depending on your particular blend

Thesis Nootropics offers a unique blend of ingredients that target thesis energy, thesis creativity, cellular function, and even skin health, making it a notable contender in the supplement industry.

For this part of the Thesis supplements review, I got my dietitian to help out and analyze the Thesis formula for each of the products.

We also tested the effects with 12 clients to see whether the marketing hype lives up to expectations.

Let's have a more detailed look at the features and benefits of each blend.

The idea behind Thesis Energy is to help people clear brain fog and feel more mentally energized.

To verify this, we paid close attention to the journal entries our testing team made in the afternoons. This is typically when people feel a slump.

What we found was that folks who took this supplement after lunch gained some mental clarity.

But it seems like the effect wears off after about four hours, so you don’t gain an all-day effect like with other nootropics.

Key Ingredients:

• Choline: According to PubMed, this mineral may boost memory function and verbal fluency [ 1 ].
• L-Theanine: A controlled trial posted in Nutritional Neurosciences suggests that this amino acid can work well with caffeine to increase alertness without causing jitters [ 2 ].
• Caffeine: This stimulant can boost alertness, but you can get this from a morning coffee, so I’m not overly impressed that it’s added here [ 3 ].

Thesis Clarity is another product that aims to improve neural communication and allow you to think more clearly and effectively.

Thesis Nootropics' clarity formula provides an extra boost of cognitive performance, targeting stress response reduction and improving sleep quality, all while delivering a healthy dose for enhanced mental clarity and improved ability.

We did note in our testing review that there seems to be an improvement in mental function for several hours after taking it.

But this also seemed to happen more with those testers who took the clarity and energy formula.

• 7,8-DHF: Studies have shown that Dihydroxyflavone can cross the blood-brain barrier and act as a neuroprotective ingredient [ 4 ].
• Alpha GPC: This is an ingredient that has been shown to protect against neurological decline [ 5 ].
• Lion’s Mane: This mushroom is common in nootropics and has been shown to improve mental performance and creativity [ 6 ].

A large part of improving mental health comes down to how focused and motivated you are with daily tasks. Our clients who tested the Thesis Motivation noted that it seemed to help them remain more motivated during workouts.

But this doesn’t seem to happen if you take it in the morning and go to the gym later in the day. So you’d need to get your timing right.

• L-Phenylalanine: Research has shown that this ingredient can help with signs of depression and improve overall mood [ 7 ].
• Dynamine: Also known as Methylliberine, studies have highlighted that it can impact your mental well-being when combined with caffeine [ 8 ].
• Forskolin: The interesting thing about this herbal ingredient is that it can improve blood flow to the brain for better focus and motivation [ 9 ].

For this product, we looked at what our clients noted in their journals when they were at work or studying. While they did find a boost in focus, none of them noted that it helped improve verbal fluency or problem-solving skills.

• Ginkgo Biloba: This is a common ingredient in traditional medicine, but modern clinical trials have shown that it can help brain health through improved blood flow and anti-inflammatory properties [ 10 ].
• Ashwagandha: This herb can have a direct impact on stress and memory, allowing you to think clearly and effectively [ 11 ].
• Saffron: It’s the most expensive herb in the world, and studies have linked it to improved stress, mood, and cognitive capacity [ 12 ].

A few of our clients tried the creativity blends, but this is one of the products where most of them didn’t report any significant improvements.

Combinations with other products above did positively impact mood and stress, but we couldn’t find any comments where our clients highlighted that they felt more creative in their work or any other creatively demanding context.

• Agmatine: This amino acid doesn’t just boost cognitive performance but may also help to protect brain cells against oxidative stress [ 13 ].
• Zembrin: Research has shown that this herb can impact both stress and anxiety, but there’s no specific evidence that it can help with creativity [ 14 ].
• Ginseng: This is a common ingredient in diet supplements as it can improve blood sugar levels, but that wouldn’t directly influence creativity [ 15 ].

We also asked all of our clients to provide any feedback they had on side effects related to the nootropic blends.

Overall, the majority of people found that it didn't cause any major issues.

We only noted that one person had a bit of a rash, which could have been a result of an allergic reaction to one of the ingredients.

We also found that it’s best not to take these capsules on an empty stomach. Ideally, take them within 20 minutes of eating a meal to avoid stomach upset.

Based on my personal experience, people who want to achieve a moderate boost in brain function may want to take nootropic supplements.

You would need to experiment with the timing as these capsules don’t provide effects for the entire day. But after about a week, you should be in a position to spread out the capsules for maximum effect.

You can also contact a coach directly for advice on timing. It's especially important when you have no prior experience in taking these supplements. However, a good starting point is to take the minimum and adjust from there.

Based on our own experience, people with high blood pressure or neurological diseases shouldn’t take Thesis natural nootropics to enhance cognitive function.

In such cases, it’s best to have a doctor review your detailed medical history and the nootropic ingredients for any potential side effects.

Our testing team didn’t note any improvements whatsoever, and when we specifically asked them after the trial, none of them said they saw a noticeable difference.

You can buy Thesis Nootropics directly from the company website.

We generally recommend avoiding third-party retailers to ensure that you always get the real product, so this is a positive highlight.

We placed two orders, and the package arrived within four days, which is about average for nootropic supplement companies.

One thing to point out on the Thesis supplements shipping policy is that currently, the company doesn’t offer international shipping.

We also had a look for other nootropic reviews online to see what users were saying.

“It gave me more energy. I have struggled with low energy and I felt like my old self again. I could get up & get things done.” - Laurie C., taketheseis.com

“After 1 month of using Energy, Creativity, Clarity and Logic pack, I do not note any difference in mindset. I opted for the non-caffeinated blends as I am not a big caffeine person to begin with so a caffeinated blend might show some improvement.” - Beefnug, Reddit

“I have been continuously nauseated every day using thesis packets. I have given it a week and a half and cannot handle the negative side effects. Disappointed.” - AdGroundbreaking5162, Reddit

Our Thesis scientific research suggests that it doesn’t compare well to our testing of three other products for improving cognitive function.

First of all, we looked at the results we have for Mind Lab Pro .

The one thing that stands out the most is that it seems to be effective for many more hours than Thesis, so the timing doesn’t become an issue.

The second one we compared is Onnit Alpha Brain . This nootropic supplement seems to provide a lot more focus and motivation, especially while you’re at the gym.

Compared to Gorilla Mind Smooth , Thesis doesn’t have the same effect on boosting energy and reducing stress.

Related Articles:

• Avantera Elevate Review
• Best Nootropics For Men
• Best Nootropics For Women

Is It Safe To Take Thesis Nootropics Every Day?

Yes, it is safe to take Thesis Nootropics every day. We found Thesis to be generally easy to process, but you need to look out for allergies to any of the ingredients. A good way to do this is to ask your physician for advice since they will know whether these ingredients are good for your health.

Does Thesis Nootropics Contain Banned Ingredients?

No, Thesis Nootropics doesn’t contain any banned ingredients. All of the ingredients are based on minerals, amino acids, and herbs that won’t cause a positive drug test result.

Based on our feedback from a nutritionist and the test results with 12 clients, we don't recommend Thesis.

Not only do its effects wear off after a few hours, which makes timing your intake a problem, but it also burns a hole in your pocket for just a stack of three or four products.

Instead, I highly recommend one of the best nootropic brands we have tested so far: Mind Lab Pro .

Our results show that its effects last for most of the day and provide great clarity, energy, focus, and concentration, making it a favorite among clients of all age groups.

We Recommend This Instead

Mind Lab Pro

• Great combination of herbs and amino acids that work as a cognitive enhancer
• Added B vitamins to support red blood cell production and boosted energy levels
• Great feedback from users that it can help with relieving anxiety
• Get the BEST PRICE until the end of August
• The capsules are not the smallest ones to swallow

About The Author

James Cunningham is an author and dietary supplement connoisseur with a solid academic foundation, holding a BSc in Sport & Exercise Science from the University of Hertfordshire. Specializing in Performance Psychology, his expertise is backed by both rigorous study and practical experience.

As an author, James is committed to guiding his readers towards optimal health and performance, providing actionable insights and strategies through his writings.

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Curious About Brain Optimization? Thesis Nootropics May Be Your In

Our product picks are editor-tested, expert-approved. We may earn a commission through links on our site. 

Ever feel like you have the ability but not the willpower or inspiration to excel at your job? Or maybe you’re stuck in a creative rut and are struggling to get yourself out. Thesis , a nootropics company, wants you to stop being so hard on yourself.

Nootropics are the buzzy brain-boosting substances of the moment, and Thesis attempts to match people to different nootropic blends designed for certain needs—creativity, confidence, energy, clarity, logic, and so on. But can you really summon the powers of creativity on demand from a pill? Myself, and fellow Edge writer Rebekah Harding, tried Thesis for three months to find out. Here’s what you need to know. 

Why You Should Trust Us

Hone Health is a team of health-obsessed journalists, editors, fitness junkies, medical reviewers, and product testers. The two authors of this review, Rebekah Harding and Will Price, spent months taking Thesis’ nootropics blends and logging how we felt. We’ve reported on the ingredients Thesis incorporates in its nootropic blends extensively, such as  ashwagandha ,  Alpha-GPC ,  Lion’s mane , and more.

For this review, we opted to review the product and service independently, as nootropics do not all affect people in the same way. Here’s what we found. 

Thesis Nootropics

Personalized recommendations.

• High quality ingredients, third-party tested

Excellent customer service

Not for everybody, what is thesis.

Thesis’s thesis (sorry, I had to) is that you are capable of more. But as co-founder and CEO Dan Freed says on the back of the box the pills come in, “…people thought I was lazy, stupid, or unmotivated. I knew there was more in me.” Freed and his brand propose that the solution to this conundrum many of us face may be nootropics, which are substances that aim to improve cognitive performance. 

New users are funneled through a quiz that determines the best nootropic blends for them—each named for the feeling they’re meant to evoke, e.g. confidence, clarity, creativity. Boxes come with four blends, each of which should last one week, with auto-renewing deliveries shipping at $79 a month. (Note: you can buy Thesis for just one month, but it will cost $119). 

You’re meant to take notes on how each blend makes you feel and, after you’ve completed your first box, adjust which blends you receive going forward.

What are nootropics?

Nootropics are medicinal substances (some pharmaceutical, some natural) that take aim at improving brain performance—memory, creativity, motivation, mood, as well as anxiety reduction and sleep improvement.

While most have heard of popular nootropics like caffeine , creatine , or nicotine , most over-the-counter nootropic supplements—like Thesis—are formulated largely with herbs, vitamins, minerals, and other natural compounds that are known to benefit the brain.

Thesis ingredients

Each Thesis blend contains different ingredients, many of which are supported by solid research. Here are a handful. 

Lion’s mane: Mushrooms that contain hericenones and erinacines, which can stimulate nerve growth and may offer potential cognitive benefits ( 1 ). In addition to thinking capacity, these mushrooms may lower the risk of age-related brain diseases, like Alzheimer’s disease ( 2 ).

Alpha-GPC: May increase your levels of a neurotransmitter called acetylcholine, which facilitates memory and learning, and plays an important role in cognitive function ( 3 ). 

L-Theanine: An amino acid that can positively affect mood. Studies have found L-theanine may be a beneficial nootropic for mood and mental health. It may also help ease anxiety and stress levels ( 4 ).  

Ashwagandha: An ancient herb taken for thousands of years, ashwagandha is an adaptogen that has been found to reduce cortisol —stress—levels in humans, which can have a number of powerful knock-on effects on the brain ( 5 ). 

DHA (Omega-3): This omega-3 fatty acid plays a role in supporting cognitive function and promoting growth and maintenance of brain cells . Research suggests that DHA may improve memory, learning, and overall cognitive performance ( 6 ). 

Synapsa: This patented extract of Water Hyssop boasts nootropic benefits such as enhanced memory and cognitive function ( 7 ). Research shows that taking Synapsa regularly may improve your information processing speed, increase your attention span and enhance your memory ( 8 ).

Ginkgo Biloba: Ginkgo Biloba has antioxidant properties, which are associated with cerebral blood flow and neuroprotection ( 9 ). Studies suggest that this nootropic may boost memory, mental clarity, and overall cognitive function ( 10 ).

Theacrine: This natural plant compound acts as a mild stimulant, without the tolerance build-up and jitters associated with caffeine ( 11 ). Theacrine may boost energy, mental clarity, and focus.

What’s Good About Thesis Nootropics?

There are a lot of folks interested in nootropics. Google reports something like 100,000 monthly searches for the term each month. The issue many have is simple: nootropics aren’t easy. 

It’s not easy to know what companies are selling legitimate products and which are pushing low-grade stuff. It’s not easy to get a handle on what the many, many different nootropics are meant to do. Sometimes it’s not easy to know if the good week you just had was thanks to a nootropic you just took, or the absence of some stressor you forgot about. Then there’s dosage, doctors, and the way in which these substances play off each other to worry about. 

Getting your foot in the door with nootropics is a challenging task. Thesis’s approach is designed to simplify this, and it largely works.

The personalization is somewhat limited, in that the blends themselves cannot be changed, but the blends you receive can. Interested customers are prompted to complete a simple questionnaire that asks about physical traits as well as your goals in taking nootropics. You’re then given a “Starter Kit” that includes four different blends suited to what you’re after. 

High-quality ingredients

The more you delve into nootropics, the more you realize there are, broadly, two classes of company: the legit class and the not-so-legit class. Thesis, by our account, is the former. The company’s products are products in FDA-approved cGMP facilities, which ensures the manufacturing of the product is sound. More importantly, though, and this will sound humorous if you’ve never shopped for nootropics, Thesis actually tells you what’s in its blends. 

Thesis is not the only company selling nootropic blends as a shortcut for people not interested in doing months of research. There are a great many companies that don’t specify ingredients (“focus blend”) or, more commonly, aren’t clear on dosage of each individual nootropic.

Thesis’s nutrition label is crystal clear on what’s inside each serving of its nootropic blend.

When launching oneself into a health category one doesn’t know much about, having a friend can be helpful and reassuring. Thesis’s customer support service—available via email or phone—is the weird science friend you need. 

I pestered them numerous times and each issue was responded to and resolved within 24 hours every time. The first time I called. Is there a way to remove the caffeine from the blends (there’s 100mg, or a cup of coffee’s worth in each pack)? You can request non-caffeinated blends on your next order, but for the time being simply don’t take the white pill in the daily dose packet. My email questions were answered with similar speed as well. 

There’s also Thesis’s coaching feature, which is effectively customer service for questions about your specific blends, how the blends make you feel, and so on. When I called into it I mentioned that some of the blends made me slightly antsy, some made me feel great, and others seemed to have no effect at all. Not only is this common, it’s expected: these substances do not affect us all in the same way, so there is a necessary trial period to get through. 

Having a source of reassurance when trying something new to improve our health makes the process more comfortable. 

MENTAL WORKOUT

What’s not good about thesis nootropics.

As previously mentioned, not all blends will work for you. Several reviews online suggest there are people for which none of them will work. My fellow reviewer and I each found one or two blends that worked especially well, some blends that didn’t seem to have any effect at all, and others that caused some minor anxiety. 

This is sort of the rub with nootropics. Different people will be hit different by different nootropics ; and even then there is the matter of dosage and duration, as most research suggests there is bedding-in period associated with nootropic effectiveness ( 12 ).

So is this a con for Thesis or for nootropic supplementation more generally? It’s a little of both, but more so a hurdle with the wider world of nootropics.

If you’re already waist deep in nootropics as a hobby or interest area, you can likely build your own nootropic stacks for cheaper than what Thesis offers.

Thesis costs $79 a month, or $3.29 per serving, once you’ve set up your account for automatic renewal. This is, unsurprisingly, on the middle-higher end of the nootropic blend market. 

Budget brands like Focus Factor come in at less than a dollar per serving. Mind Lab Pro , a brand closer to Thesis’s efficacy and quality, goes for about $2.10 per serving. The popular NooCube blend is also about $2.15 per serving. 

It should be said that I’m obviously comparing apples to oranges here. Each of these blends are made of up different stuff. Each of these companies is selling to a different customer. It could be argued that Thesis’s hyper responsive customer service and task-focused personalization model makes the $79 a month bill a fair deal. That said, the price doesn’t pull you in quite like the promise the rest of the product provides. 

What It’s Like to Take Thesis Nootropics

Tester #1 info : Female, 23 years old Reason for taking : diagnosed ADHD, brain fog, difficulty concentrating, anxiety Blends taken : Confidence, Motivation, Energy, Clarity

When I was diagnosed with ADHD in 2016, everything clicked. I’ve struggled with brain fog, task paralysis, and extreme difficulty concentrating for as long as I can remember. But all I have to show for my diagnosis is a raging caffeine addiction, two failed tries at taking prescription stimulant medication, and an ever-changing-never-working supplement stack.

As a neurodivergent person, the idea of nootropics—supplements that may improve cognitive performance—is intriguing to me. The idea of spending hours researching different blends and stand alone supplements, however, is not. That’s where Thesis comes in. 

To order your four-blend starter kit, Thesis kicks things off with a quick 25-question quiz. The questions were quick and multiple choice, and didn’t take more than a couple of minutes. (As a company that markets to ADHD-ers, I have to say they know their audience.) The quiz covers questions like how much sleep you clock in each night, your typical mood, and your procrastination habits—and a memory test at the end that I won’t spoil. At the end, you plug in an email and receive a customized recommendation based on your goals and struggles. 

I’m ultra-productive, but I have extreme anxiety and frequent brain fog depending on the state of my hormones. Thesis recommended four blends—Confidence, Motivation, Energy, and Clarity—to boost my mental health, promote relaxation, and fight off brain fog. 

I took each blend for six days each—as directed—with one day in between to reset.

Week one I opted for Confidence—a blend that includes saffron, ashwagandha, sage, and magnesium—which oddly produced the opposite of its intended effect. Two days in, I ditched the separate, white caffeine pill in the packet, but that only alleviated my anxiety slightly. Week two, I took Motivation—which contains artichoke extract, vitamin B12, methylliberine, and L-theanine. I enjoyed this blend the most, and felt like my mood and concentration got a decent boost. Weeks 3 and 4 I took Energy (mango leaf extract, theacrine, citicoline, and more) and Clarity (Lion’s Mane, L-theanine, and more) respectively. I noticed no changes these weeks.

Overall, I think Thesis is worth a shot for the nootropic-curious. Especially if you don’t have the time or patience to research these trendy supplements. However, I don’t think I’ll be stocking up on any of their blends any time soon.

BRAIN GAMES

Tester #2 info : Male, 30 years old Reason for taking : brain fog, unfocused, spark creativity Blends taken : Clarity, Logic, Creativity, Energy

I’ve not been evaluated for or diagnosed with any neurological or neurodevelopmental matters, but I have struggled to train my mind’s gaze on one thing for long periods of time for as long as I can remember. Call it brain fog or something else, it’s been a persistent issue of mine going back to my high school and college years, where I’d substitute just about any distraction available to me instead of something that would require real attention.

A Thesis ad on Instagram suggested this issue may not be my own failing (a source of great personal anxiety), but perhaps something that could be fixed with nootropics. I’m willing to believe most anything that suggests my failings are not my failings, so I ordered my personalized starter kit. 

My kit came with the Clarity, Logic, Creativity, and Energy blends. I quickly eliminated Clarity and Logic from the rotation, and both seemed to trigger a mix of uncomfortable headaches and anxiety (a quick browse of the internet suggests this isn’t an uncommon reaction to these specific blends). Energy, while effective, wasn’t the most useful to me, someone who doesn’t struggle as much with alertness. 

Creativity was different, though. During the second month of testing, once I’d taken Creativity for a few weeks straight (remember there is a bedding-in period!), things started to click. I started to feel the gears turning a bit more in brainstorm meetings at work, and I could think more deeply about how I could build a workout plan for a friend.

That’s how I would describe the feeling: a noticeable but slight improvement in my ability to untangle a problem of some kind. It wasn’t as though the shackles of my brand were removed and I launched a Fortune 500 company which, thankfully, Thesis does not suggest in any of its marketing materials. 

I’ve taken the Creativity tablets for a few months now and find them to be good value for the money, for me. For those curious about nootropics, I think of Thesis as the ideal first stop. Once you figure out what works for your brain and needs, you might seek out other solutions. 

The Bottom Line

Thesis nootropics are probably the best way to get into nootropics without having to do loads of research. The brand isn’t the cheapest out there, but the product is quality and the customer service is excellent.

• Lai, Puei-Lene et al (2013) https://pubmed.ncbi.nlm.nih.gov/24266378/
• Skubel Tomasz et al (2022) https://www.researchgate.net/publication/363300485_Therapeutic_potential_of_Lion
• Ham, Juhee et al (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645066/
• Williams, Jackson L. et al (2019) https://pubmed.ncbi.nlm.nih.gov/31758301/
• Lopresti, Adrian L. et al (2019) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/
• Yurko-Mauro, Karin et al (2015) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364972/
• Downey, Luke A. et al (2012) https://pubmed.ncbi.nlm.nih.gov/23281132/
• Kumar, Navneet et al (2016) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075615/
• Mashayekhu, Ameneh et al (2012) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163160/
• Ge, Wei et al (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8014356/
• Bello, Marissa L. et al (2019) https://jissn.biomedcentral.com/articles/10.1186/s12970-019-0287-6
• Malik, Matej et al (2022) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415189/

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Thesis Nootropics Review: Unveiling the Effects on Cognitive Enhancement

Nootropics , often referred to as “smart drugs” or cognitive enhancers, have gained popularity for their potential to improve mental functions such as cognition, memory , intelligence, motivation, attention, and concentration . As an avid researcher in the field of cognitive enhancement , I have come across various products that claim to offer these benefits. Thesis, a company that provides personalized nootropic stacks, presents a unique approach to cognitive enhancement by customizing supplements to match individual needs and goals.

My personal journey with nootropics led me to investigate Thesis Nootropics further. Their promise hinges on the tailoring of their product to the user’s specific cognitive profile. This level of customization is intended to maximize the benefits while minimizing potential side effects. In reviewing Thesis Nootropics, I examined the ingredients used, the science behind them, the efficacy as reported by users, and how they compare to other products in the market.

Key Takeaways

• Thesis provides personalized nootropic stacks to enhance cognitive functions.
• Customization of supplements is designed to optimize benefits and reduce side effects.
• Examining user experiences and comparative analysis is crucial in evaluating Thesis Nootropics.

Understanding Nootropics

Nootropics, often referred to as “smart drugs,” have garnered attention for their potential cognitive benefits . I’ll give you an overview of their history and types, specifically focusing on natural versus synthetic variants.

History and Definition

Nootropics, a term coined in 1972 by psychologist Corneliu E. Giurgea, refer to substances that can improve mental performance. Initially, nootropics were associated with compounds that met very specific criteria that include the enhancement of learning and memory while providing protection to the brain under various conditions. The concept has since expanded to include a variety of nootropic supplements that claim to boost cognitive functions such as memory, creativity, and motivation.

Natural vs. Synthetic

Natural nootropics are compounds found in nature such as herbs and plant extracts that may offer cognitive enhancements. Common examples include:

• Ginkgo Biloba: Often used with an aim to improve memory.
• Panax Ginseng : Sought for its potential to boost brain function.

Conversely, synthetic nootropics are manufactured compounds like racetams and amphetamine derivatives. They include:

• Piracetam: The first synthetic nootropic, designed to aid in memory and learning.
• Modafinil: Prescribed for sleep disorders but often used off-label for its concentration-enhancing effects.

Both types aim to offer cognitive benefits, but their effects and mechanisms can widely differ. Natural nootropics are typically preferred by those seeking milder effects and a more holistic approach, whereas synthetic ones are chosen for their strong, targeted actions.

Thesis Nootropics Specifics

I’ve researched Thesis Nootropics intricately to provide accurate details on their product lineup, the customization process, and the intricacies of their subscription model.

Product Offerings

Thesis Nootropics presents a range of dietary supplements, each targeting specific cognitive functions. Their offerings typically include Thesis Energy , designed to boost stamina and focus , Thesis Clarity , intended to enhance cognitive sharpness, and Thesis Motivation , aimed at increasing users’ drive and productivity. The ingredients in these supplements range from natural extracts to amino acids , all selected for their potential nootropic properties.

• Thesis Energy : Ingredients such as caffeine and L-theanine
• Thesis Clarity : Includes nootropics like Rhodiola Rosea
• Thesis Motivation : Features compounds such as sulbutiamine

Thesis Customization

The cornerstone of Thesis Nootropics is personalization. Upon embarking on their nootropic journey, customers receive a starter kit which allows them to test different ingredients and track their effects. This process is critical in developing personalized blends that match individual cognitive needs and goals. I appreciate that this approach acknowledges biological uniqueness and optimizes supplementation for personal effectiveness.

Subscription Model

Thesis offers their nootropic supplements through a monthly subscription model. After the initial starter kit evaluation phase, customers receive monthly deliveries of their tailored supplements. Subscriptions provide convenience and ensure continuous use for consistent cognitive support. This model necessitates a commitment but also emphasizes regularity in pursuing cognitive enhancement.

• Monthly Deliveries: Ensures a steady supply of personalized nootropic blends
• Subscription Cycles: Typically require a monthly payment with the flexibility to pause or cancel

The focus on specifics ensures that you possess a clear understanding of what Thesis Nootropics brings to the table in terms of products, customization, and purchase options.

Benefits and Efficacy

In evaluating Thesis Nootropics, I’ve found that the primary benefits are centered around enhancing cognitive function and managing mood and stress, both essential for optimal mental performance.

Cognitive Function Enhancement

Energy & Concentration: Users report heightened energy levels, which appear to correlate with an increased ability to focus and maintain concentration. This makes tackling complex tasks somewhat easier.

Memory & Clarity: Memory recall and mental clarity are also areas where Thesis Nootropics shows potential. My review notes improvements in these domains, supporting better retention of information and clearer cognitive processing.

Motivation & Creativity: There’s mention of an uptick in motivation, alongside a conducive environment for creativity. This is pertinent for those requiring innovative thinking in their daily activities.

Mood and Stress Management

Mood Improvement : Regular intake of Thesis Nootropics may lead to a stabilized and improved mood, as suggested by my analysis and user testimonials. This is vital for sustained cognitive performance.

Stress Reduction: Stress levels reportedly see a downward trend with these nootropics. My observations concur, and lower stress is indispensable for reducing cognitive friction and the dreaded brain fog.

Potential Side Effects and Safety

In assessing the side effects and safety of Thesis Nootropics, I focus on the documented experiences of users and the available clinical evidence supporting safety claims.

Common Concerns

Side effects : In my examination, users have reported various side effects that may include headache , anxiety, and jitteriness—typically associated with products containing caffeine . While individual tolerance varies, I have observed these reports to be relatively infrequent.

• Headache : Possible in sensitive individuals or new users.
• Anxiety : Can occur, particularly in formulations with high stimulant content.
• Interactions : As with any supplement, a check for potential interactions with prescription medication is prudent.

Clinical Evidence

Clinical Trials : Thesis Nootropics’ safety profiles are often supported by studies on individual ingredients rather than on the products themselves. Comprehensive, product-specific clinical trials that are peer-reviewed and FDA-recognized remain limited.

• Caffeine : Investigations affirm it’s generally safe in moderate amounts; however, excessive intake can lead to side effects.
• FDA Oversight : Dietary supplements like Thesis Nootropics are not as stringently regulated as prescription medications, hence the FDA does not approve them. However, safety can be inferred from the FDA’s guidelines on individual ingredients.

Comparative Analysis

In this section, I examine how Thesis Nootropics stack up against other prominent brands in the market and assess their value for money.

Thesis vs. Other Brands

Thesis Nootropics stand out due to their personalized approach to cognitive enhancement. Customers complete an assessment that tailors the nootropics stack to their individual needs.

• Mind Lab Pro offers a universal nootropic aiming to target all areas of cognitive function without personalized stacks. It has received acclaim for its comprehensive formula .
• Onnit’s Alpha Brain is another competitor, well-known for celebrity endorsements and a formula that supports memory, focus, and cognitive processing without the need for personalization.

When looking at customer reviews , Thesis seems to have a strong following due to its bespoke service. On the other hand, both Mind Lab Pro and Alpha Brain have amassed numerous reviews praising their effectiveness for a broader audience.

Pros of Thesis: personalized approach, tailored benefits. Cons of Thesis: may be costlier due to customization, less known than other brands.

Pros of Mind Lab Pro: broad-appeal formula, strong market presence. Cons of Mind Lab Pro: lacks personalization, potential overkill of ingredients for some.

Pros of Alpha Brain: popularized by endorsements, focus on cognitive processing. Cons of Alpha Brain: potential variability in individual results, less tailored experience.

Cost-Benefit Consideration

When I consider the price of Thesis, it is generally on the higher side due to the personalized nature of the product. However, my logic dictates that the cost could be justified if the tailored stacks lead to more noticeable improvements in cognitive function.

• Thesis sells their personalized nootropics starting at a certain price point that can go up depending on the customization.
• Mind Lab Pro comes at a set price, positioning itself as a one-size-fits-all solution, potentially more cost-effective for those not seeking personalization.
• Alpha Brain is similar to Mind Lab Pro in pricing but frequently offers deals and discounts which may make it a more attractive option for budget-conscious consumers.

To decide if Thesis is worth it , compare:

• Price: Higher for customization.
• Buy: Direct and through subscriptions for ongoing benefits.
• Reviews: Positive for the personalized approach.
• Comparison: More expensive than some, but the cost is justified for users who value bespoke formulas.

The deciding factor often comes down to whether an individual prefers a personalized approach or a generalized formula that has been traditionally popular in the market.

User Experience and Reviews

In this section, I will provide a detailed look at what consumers and professionals are saying about Thesis Nootropics. I seek to offer a balanced and informed perspective on the real-world impact these supplements have on cognitive performance.

Customer Testimonials

Thesis Nootropics have been met with a broad spectrum of feedback from users who typically emphasize gains in focus, clarity, and energy levels. Below is a curated selection of customer testimonials:

Professional Opinions

In the realm of expert analysis, coaches and neuroscientists have offered their professional outlook on Thesis Nootropics. The consensus is that these supplements provide a tailored approach to cognitive enhancement, by customizing nootropic blends to individual needs.

• Dr. Aiden Smith, Neuroscientist : “Thesis Nootropics offer an innovative approach to cognitive support, backed by scientific research in neurology.”
• Coach Jennifer Lynn , Cognitive Performance Coach: “My clients report clear, sustained focus and improved mental energy when incorporating Thesis into their wellness routine.”

Frequently Asked Questions

In this section, I provide answers to some of the most common inquiries regarding Thesis nootropics. I focus on ingredients, comparisons with pharmaceuticals, potential benefits, side effects, user feedback, and top-rated alternatives for cognitive enhancement.

What are the main ingredients in Thesis nootropics and how do they work?

The main ingredients in Thesis nootropics include a range of vitamins, amino acids, and herbal extracts, each serving a specific function. Ingredients like Rhodiola and Bacopa enhance memory and focus, while L-Theanine and caffeine stimulate alertness and cognitive performance.

How do Thesis nootropics compare to Adderall in terms of effects and safety?

While Adderall is a prescription medication primarily used to treat ADHD, Thesis nootropics are over-the-counter supplements aimed at boosting cognitive performance. Adderall contains amphetamine salts, which have a significant impact on neurotransmitters but also carry a higher risk of side effects and dependency. Thesis nootropics offer a milder, non-prescription alternative with a focus on safety and minimal side effects.

Can Thesis nootropics potentially improve attention and focus in individuals with ADHD?

Some users with ADHD may find the ingredients in Thesis nootropics beneficial for improving attention and focus. However, Thesis products are not approved as a treatment for ADHD by the FDA, and individuals with ADHD should consult with a healthcare provider before using these supplements.

What are the reported side effects of taking Thesis nootropics?

The reported side effects of Thesis nootropics tend to be mild and can include jitteriness, stomach upset, or headaches. These are typically dosage-dependent and can often be mitigated by adjusting the intake.

How effective are Thesis nootropics according to user reviews?

User reviews generally suggest that Thesis nootropics are effective for enhancing cognitive functions such as focus, memory, and mental clarity. Effectiveness can vary individually, but many users report noticeable improvements after consistent use.

What nootropic is considered the highest-rated for cognitive enhancement?

While individual experiences may vary, many users and experts consider modafinil to be one of the highest-rated nootropics for cognitive enhancement. It is often praised for its ability to increase wakefulness, focus, and productivity. However, it is important to note that modafinil is a prescription medication and should be used under medical supervision.

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Thesis Nootropics Review – Pros, Cons, and Verdict

By Jack Cincotta, MS

Reviewed by Juliana Tamayo, MS, RDN - Last Updated February 15, 2023

Some of the links in our articles are from our advertisers.  Learn more about how we make money .

I’m betting you’ve heard the word “nootropics” thrown around lately, especially if you have an interest in brain enhancement. 

The nootropics industry is exploding in popularity as people are trying to use these various brain boosters to improve focus , increase energy, and even enhance intelligence. 

As a holistic health practitioner, I’m pretty intrigued by the possible benefits, but I also know that they need to be scientifically backed and supported by evidence. And let me tell you straight up that not every supplement that claims to be a nootropic is a legitimate brain enhancer.

That’s why I’m going to go over all of the details of the Thesis Nootropics line to let you know if these are actually worth using. So, keep reading my Thesis Nootropics review to see what nootropic formulas they offer, the specific ingredients, potential benefits, and more!

About Thesis Nootropics

Thesis Nootropics is not one particular supplement but rather a nootropic brand that has a line of five different nootropic supplements. 

They offer personalized nootropic formulas to activate the potential in you, no matter what your brain chemistry looks like. They recommend that you go through a quick process in order to get the most personalized nootropic formulas.

This is somewhat similar to other personalized nootropics, such as Find My Formula . 

The Process

First, you are directed to take a unique quiz so they can learn more about your individual situation. You are asked basic info such as age and weight; and then they ask what your main goals are for using nootropics.

Then, they ask many questions related to your lifestyle habits, such as sleep, exercise, and caffeine intake. After that, they inquire about the degree to which you struggle with various things in day-to-day life, such as memory issues, low mood, motivation, confidence, and focus. 

The quiz only takes a few minutes to complete. And after you finish it, Thesis Nootropics recommends four distinct nootropic formulas that they think will work best for you. 

You are instructed to take just one of the four for one week, and then repeat the process with the other three for the rest of the month. 

After that, you let them know which ones worked best and they’ll help you optimize your stack even further.

What are the Specific Thesis Nootropics Formulas?

Thesis Nootropics has six possible formulas that you could be recommended after the quiz:

These have unique combinations made up of several of the 30+ ingredients that Thesis Nootropics offers. Most products typically have around 5 ingredients in total. 

Thesis Nootropics Benefits

The benefits you get from Thesis depends on which formulas you’re recommended. But generally speaking, here are the main possible benefits of using Thesis Nootropics :

Enhanced Learning & Memory

Increased energy, improved mood & motivation, more focus & clarity, reduced stress, brain protection.

A lot of people start to have memory issues in middle to late adulthood. But these aren’t the only people who want improved memory. Even younger individuals want to increase learning and memory abilities to maximize their performance in school or work.

Thesis Nootropics are designed to boost learning and memory processes in the brain. Several ingredients may play a role here, such as Alpha-GPC and TAU (uridine). They’re designed to increase acetylcholine and improve neural connections, among other mechanisms.

Many individuals need an energy boost to start the day and/or in the late afternoon. Yet, you may want a healthier, more natural alternative to energy drinks.

Well, Thesis Nootropics has many ingredients that may increase energy, such as caffeine, theobromine, and Panax ginseng. These may boost stimulating neurotransmitters, such as noradrenaline, to help keep you alert and energized. 

Mental health problems are very common. Even if you don’t have clinical symptoms, low-level things such as poor mood, anxiety, and motivation certainly make it hard to enjoy life and become your best self.

Thesis Nootropics are meant to boost your mood and improve motivation, mainly by increasing dopamine and serotonin, so you can attack the day with full force. Whether that’s for a work project, school exam, or simply taking care of daily tasks.

This line has many ingredients that may boost mental well-being, such as zembrin, saffron, and magnesium. 

Brain fog, distractions, and lack of attention can all greatly decrease your productivity and efficiency. But unfortunately, there are so many things that can cause these problems, with everything from phone notifications, social media and other apps, and even certain foods you eat (if you’re sensitive).

But Thesis Nootropics claims to put an end to brain fog and poor concentration. They have many different ingredients that are advertised to boost acetylcholine and engage other key brain processes involved in focus, mental clarity, and attention. Such ingredients are theanine and tyrosine, among several others.

In today’s fast-paced world, a lot of folks have very high stress levels. And this can cause decrements in cognitive performance and overall well-being over time.

Thesis Nootropics are meant to reduce physical and mental stress on the body and help restore balance. They have many different ingredients, such as ashwagandha and phosphatidylserine to decrease cortisol and balance the body’s stress response.

Life can definitely take a toll on overall brain health. Over time, inflammation and oxidative stress caused by poor diet and lifestyle habits may increase the risk of brain damage and poor function.

But Thesis Nootropics are advertised to protect the brain from damage and preserve its optimal function. This is due to several compounds, such as sage, magnolia, and bacopa monnieri. 

Are Thesis Nootropics Legit?

There are a wide variety of proposed benefits from Thesis Nootropics . And you may be wondering if they are actually legit.

Well, as a holistic health practitioner, I can tell you that Thesis definitely seems legit because they use many different well-researched ingredients. And they also take steps to ensure product safety and quality. 

But if you want to know whether Thesis Nootropics actually work , keep reading my Thesis Nootropics review!

Thesis Nootropics Ingredients

Thesis Nootropics has 31 ingredients that could possibly be recommended to you in your four formulas.

Now, you won’t have all 31 ingredients, just a blend of the ones that are most important for your goals and other factors, based on the quiz you took. 

Since there are so many ingredients, I will be grouping them together based on their main actions and functions. 

Below are all of the ingredients in Thesis Nootropics :

• Theobromine
• Phenylalanine
• Phosphatidylserine

Ginkgo Biloba

Lion’s mane 8:1.

• Epicatechin
• Vitamin B12
• N-Acetyl Cysteine
• Forskolin 20%
• Artichoke Extract 5%

GS15-4 Panax Ginseng

• Triacetyluridine

Synapsa Bacopa

Ksm-66 ashwagandha.

• Magnesium Bisglycinate
• Sage Extract
• Magnolia Bark Extract

I will go over the main compounds that have the most research. And I’ll also list other compounds that are similar in action to the main ones. 

Alpha-GPC is a bioavailable choline compound. It can increase acetylcholine in the brain, which may improve memory, enhance attention, and prevent cognitive decline.

Other similar ingredients: Choline.

Caffeine is a stimulant that blocks adenosine and increases serotonin, dopamine, noradrenaline, and other stimulating neurotransmitters. This may lead to increased energy, alertness, and motivation, among other cognitive functions. 

Note that there are caffeine-free options for Thesis Nootropics too, which use similar, but less-stimulating alternatives. 

Other similar ingredients: Theobromine, Dynamine, TeaCrine

L-tyrosine is a precursor to dopamine and noradrenaline, which are involved in motivation, alertness, and energy. Tyrosine supplementation may help restore these brain chemicals during periods of stress, which could help with cognition and physical performance during stress. 

Other similar ingredients: Phenylalanine, phosphatidylserine

Ginkgo biloba is an herb with many bioactive flavonoids and other components in the leaves. It seems to reduce oxidative stress, enhance blood flow in the brain, and increase dopamine.

There is some evidence that it boosts cognitive functions while reducing the risk of dementia and other cognitive problems.

You’ll find this in many other nootropics, such as Qualia Mind.  

Other similar ingredients: Forskolin, artichoke extract

Zynamite is a trademarked form of mango leaf extract. It is rich in polyphenols, and there is evidence that it boosts information processing, memory, and attention. 

Sabroxy is a trademarked form of oroxylum, which is an herb that’s been used in Ayurveda for many years. It has a lot of antioxidants in it and also seems to increase dopamine and GABA. 

Clinical trials show that this compound increases working memory, learning ability, and other cognitive functions. 

GS15-4 is a trademarked Panax ginseng compound. Panax ginseng is an herb with a huge history of use in Traditional Chinese Medicine (TCM). It contains ginsenosides and other active compounds that decrease inflammation in the brain, reduce stress, and increase acetylcholine and other neurotransmitters.

Overall, Panax ginseng appears effective for mood, energy, and various cognitive functions, such as learning and memory. 

Many other similar products have Panax ginseng too, such as Performance Lab Mind .

Synapsa is a trademarked form of bacopa, which is a traditional herbal compound with many uses. It contains bacosides and other bioactives that boost acetylcholine, serotonin, and dopamine, while also enhancing blood flow and reducing oxidative stress in the brain.

As a whole, bacopa seems effective for enhancing memory, learning, mood, and neuroprotection. 

KSM-66 is a trademarked ashwagandha compound. This herb has been used in Ayurveda for many years. Withanolides and other bioactives in ashwagandha help the body restore balance during stress. It also boosts GABA and other neurotransmitters.

Overall, ashwagandha may help with attention, brain function, mood, and stress reduction.

Other similar ingredients: Magnolia bark extract, sage extract. 

Affron is a trademarked form of saffron, which is an herb with many possible benefits. It has anti-inflammatory effects and also increases serotonin in the brain.

Clinical evidence shows that saffron is effective in reducing anxiety and depression, improving mood, and reducing stress. 

Other similar ingredients: Zembrin

Lion’s mane is a medicinal mushroom with many health-boosting components. It reduces stress in the brain and also increases brain-derived neurotrophic factor (BDNF), which is a critical molecule involved in neuroplasticity and overall brain function.

There is evidence that lion’s mane is helpful for reducing cognitive impairments, protecting the brain from damage, and reducing depression.

Avantera Elevate is another one of many brain-boosting supps that contains this ingredient.

L-theanine is an amino acid found in tea leaves. It increases alpha waves in the brain and supports serotonin and GABA production.

Evidence shows that theanine can help reduce stress and anxiety, improve sleep, and boost cognitive functions (e.g. attention, alertness) especially when paired with caffeine. 

Does Thesis Nootropics Work?

It is likely that Thesis Nootropics will work. They have a really high-quality line of clinically-researched compounds. 

These support many areas of brain health and function, such as memory, attention, learning, mood, stress support, energy, and focus.

It’s also nice that they have personalized formulas to give you what you need specifically. Now, these aren’t so specific that they create a different formula for EVERYONE (otherwise, there would be millions of products). But they do still take time to recommend only the formulas that may work the best for you. 

Claims vs. Reality

It’s important to be realistic with nootropics compounds. Many people think that taking these will suddenly turn them into a superhuman that can access unlimited brain power.

While this won’t occur, Thesis still should provide moderate benefits. I’ve read some of the Thesis reviews from customers too. And they’ve noted increases in energy and focus, less stress, decreased brain fog, better attention, and other benefits.

Basically, Thesis Nootropics will likely help you feel, think, and perform moderately better than you had been before. And it also depends on how much you were doing initially to optimize your brain power too. 

Who is Thesis Nootropics Best For?

There are six different Thesis products (technically 12 if you count the caffeine-free options too), so it suits a wide variety of people. 

But basically, Thesis Nootropics are for anyone who wants to increase their performance, cognitive functions, and brain power on a regular basis.

How to Take Thesis Nootropics

As a reminder, Thesis gives you four of their products based on your unique profile. You are instructed to take just one of these each week for the first month to see which two work best for you.

They say to take Thesis right away in the morning. And if needed, you can take another serving after lunch.

Is Thesis Nootropics Safe?

There are many ingredients in Thesis Nootropics, but none of them are associated with significant long-term side effects. 

Of course, side effects are always possible. Some users may experience:

• Digestive symptoms, such as bloating, upset stomach, gas
• Increased anxiety, nervousness, jitters, or sleep problems 
• Changes in blood pressure or heart rate
• Blurred vision

This isn’t an exhaustive list. We always recommend talking with your doctor before taking any supplement.

Also, Thesis supplements are made in an FDA-approved, GMP-certified facility. And they are third-party tested for purity and quality. 

Thesis contains vegan ingredients and doesn’t contain gluten, eggs, or nuts, although some facilities process products that have those three ingredients. It is not certified gluten-free or vegan. And the Logic blend contains soy.

Where to Buy Thesis Nootropics

You can buy Thesis Nootropics on the Thesis website . 

As a reminder, you get four products with each purchase.

The regular one-month supply of Thesis Nootropics is $119 ($3.97 daily) , but you can save $40 by choosing the Subscribe & Save option, which brings it down to $79 per month ($2.63/day) . 

This is a pretty expensive line of nootropics, but they are meant to be all-inclusive. And they truly do offer many ingredients in each formula, so you likely don’t need to buy any other brain supplements. 

All in all, it depends on how invested you are into nootropics and if the benefits are worth it.

Get the BEST deal

Thesis Nootropics

• Formula can include 31 possible ingredients
• Six different products offered
• Benefits memory, energy, mood, focus, stress, and brain health

Final Verdict: Thesis Nootropics

That’s the end of my Thesis review.

These nootropic supplements are filled with evidence-based ingredients that support a wide variety of cognitive functions. There are compounds for energy, focus, attention, neuroprotection, mood, and much more. 

I also like that they’re individualized and you can figure out which ones are the best for you. Because that’s what it really should be; finding the supplements that work the absolute best for your own unique brain chemistry, lifestyle, personality, etc.

So, anyone interested in trying out Thesis Nootropics can start by taking the quiz here . 

Jack Cincotta, MS

Jack Cincotta is a certified holistic health coach through AFPA and a board-certified holistic health practitioner through AADP. He has written hundreds of articles on nutrition and supplementation. Jack has a M.S. degree in Psychology and is passionate about researching the science behind nutrition. He often uses research-backed supplementation protocols for many of his clients to optimize results.

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© 2024 Fitness Clone

Fitness Clone does not provide medical advice, diagnosis or treatment.

Thesis Nootropics Review: Unveiling the Brain-Boosting Effects

In recent years, you may have noticed an increasing interest in nootropic supplements designed to enhance cognitive function and mental performance. One such product gaining attention is Thesis Nootropics . This article will provide you with an in-depth review of Thesis Nootropics, highlighting the features and benefits that set it apart from other products in the market.

Thesis Nootropics offers a personalized approach, using a unique algorithm to design a nootropic stack tailored specifically to your individual needs and circumstances. This is based on a set of questions that assess your personal requirements, allowing for a customized experience that aims to improve cognitive function, mental stamina, mood, and overall mental energy levels.

An important feature of Thesis Nootropics is the inclusion of adaptogenic herbs, such as Rhodiola Rosea and Ashwagandha, which are known for their stress-reducing properties and ability to promote relaxation. In addition to these adaptogenic herbs, Thesis Nootropics contains a variety of other ingredients designed to boost overall cognitive function.

What is Thesis Nootropics?

Thesis Nootropics appears to be a brand of dietary supplements that are designed to enhance cognitive function and mental performance. These supplements are formulated with various natural and synthetic ingredients that are thought to improve brain health, focus, memory, and mental clarity.

Furthermore, Thesis Nootropics claims to use clinically researched ingredients and the latest scientific advancements in the field of cognitive enhancement to provide safe and effective products. Some of the ingredients that Thesis Nootropics uses in their supplements include caffeine, L-theanine, bacopa monnieri, and alpha-GPC, among others.

Understanding Nootropics

Nootropics , also known as smart drugs, are compounds designed to enhance your cognitive abilities. They help in various aspects like motivation, creativity, mood, memory, focus, and cognitive processing. These substances can be divided into several categories, including herbs, amino acids, and minerals.

Nootropics work by impacting your brain’s neurotransmitters , which are responsible for transmitting signals between nerve cells. By enhancing the communication between these cells, nootropics can improve cognitive functions like memory, attention, and learning. This, in turn, can lead to better overall brain performance and mental agility.

Key Ingredients for Thesis Nootropics

Thesis Nootropics offers an impressive list of powerful ingredients to enhance your cognitive abilities, mood, and focus. We will discuss some of the primary components here that work synergistically to deliver significant benefits.

• L-Theanine is a well-known amino acid found primarily in green tea. It is widely recognized for reducing anxiety and promoting relaxation without causing drowsiness.
• Ashwagandha is another potent ingredient for stress management. This ancient herb improves memory and reduces stress levels, facilitating efficient and clear thinking.
• Ginkgo Biloba is a traditional medicine ingredient known for improving blood flow and boasting anti-inflammatory properties.
• Phosphatidylserine supports healthy brain cell membranes and promotes efficient neurotransmission.
• Lion’s Mane , a functional mushroom known for its cognitive enhancement properties, promoting neuronal growth and improving overall brain health.
• Alpha GPC , which help in the synthesis of Acetylcholine, an essential neurotransmitter that supports learning, memory, and concentration.
• Dynamine boosts alertness, energy, and focus.
• Artichoke extract supports overall heart health and provides potent antioxidant protection.

With this carefully selected combination of key ingredients, Thesis Nootropics aims to provide you with the necessary brain boost you need for enhanced cognitive performance and overall well-being.

Benefits and Effectiveness of Ingredients

• Reduced psychological and physiological stress response . L-theanine is known for its ability to promote relaxation and reduce anxiety without causing drowsiness. This may help to improve focus and cognitive performance.
• Improved memory and cognitive function . Ashwagandha is a potent adaptogen that is traditionally used in Ayurvedic medicine to help the body cope with stress. It has also been shown to improve memory and cognitive function.
• Improved blood flow . Ginkgo biloba is a traditional medicine ingredient that is thought to improve blood flow to the brain, which can help to improve cognitive function. It also has anti-inflammatory properties that may help to reduce inflammation in the brain.
• Healthy brain cell membranes and efficient neurotransmission . Phosphatidylserine is a phospholipid that is found in high concentrations in the brain. It supports the healthy structure and function of brain cell membranes and helps to promote efficient neurotransmission.
• Cognitive enhancement and overall brain health . Lion’s Mane is a functional mushroom that has been shown to promote neuronal growth and improve overall brain health. It may also enhance cognitive function, memory, and concentration.
• Increased alertness, energy, and focus . Dynamine is a natural compound that is similar in structure to caffeine. It may help to improve alertness, energy, and focus without the side effects of caffeine, such as jitters and anxiety.
• Overall heart health and antioxidant protection . Artichoke extract is a rich source of antioxidants that help to protect the body against oxidative stress. It also contains compounds that may help to support overall heart health by reducing cholesterol levels and improving blood flow.

Customizing Your Thesis Nootropics Experience

In order to get the most out of your Thesis Nootropics experience, a few key components are combined to create a personalized plan. This section will discuss four sub-sections: Thesis Questionnaire, Thesis Coaches, Thesis Starter Kit, and the TakeThesis.com Algorithm.

Thesis Questionnaire

Upon beginning your Thesis Nootropics journey, you’ll be prompted to complete a questionnaire which will assess your needs and goals. Your answers will be vital in determining the most suitable Thesis custom blend for your unique situation. As a result, it’s essential that you provide accurate and honest responses in order to receive the most effective recommendations.

Thesis Coaches

Once you have completed the questionnaire, you will have the opportunity to connect with experienced Thesis Coaches. These professionals are available to provide guidance, answer questions, and suggest the best ways to maximize your Thesis Nootropics experience. By communicating with a Thesis Coach, you can ensure that you’re getting the most out of your customized nootropics plan.

Thesis Starter Kit

Based on the results of your questionnaire and the advice of your Thesis Coach, you’ll be provided with a recommended Thesis Starter Kit. This kit contains a selection of custom blends designed to help you achieve your unique goals. Remember that consistency is key, so make sure to follow the suggested usage instructions for optimal results.

Pros and Cons

When considering Thesis Nootropics, it’s important to weigh the pros and cons of their products. Keep in mind that nootropic supplements impact individuals differently, and your experience may vary depending on your personal needs and goals.

• Elevated mood . Ingredients like L-Theanine and Ashwagandha in Thesis Nootropics may help elevate mood and reduce symptoms of anxiety and depression.
• Lowered stress levels. The adaptogenic herbs in Thesis Nootropics, such as Rhodiola Rosea and Ashwagandha, are known for their ability to lower stress levels and promote relaxation.
• Personalized blends . Unlike other nootropic supplements that use a one-size-fits-all approach, Thesis offers personalized nootropics tailored to your individual needs and goals.
• Potential side effects . As with any supplement, there’s a risk of experiencing side effects when taking Thesis Nootropics. Some common side effects to watch out for include heartburn, headaches, confusion, dizziness, loss of appetite, and digestive issues.
• Effectiveness . While some people may experience noticeable benefits from using Thesis Nootropics, others may not feel any significant impact. 

As you weigh these pros and cons, remember that personal experience varies, and it’s essential to carefully monitor how these nootropics affect you.

Safety and Efficacy of Thesis Nootropics

Your search for a nootropic supplement that supports cognitive health might have led you to Thesis Nootropics. Before diving into its benefits, it’s crucial to understand its safety and efficacy.

Thesis Nootropics utilizes ingredients that have undergone clinical research, ensuring minimal side effects and a good chance of being safe for most people. It’s important to note that, with nearly three dozen ingredients in its catalog, not all of them may be safe for every user.

FDA Regulations

Keep in mind that nootropics, like other dietary supplements, are not regulated by the Food and Drug Administration (FDA). As a result, supplement manufacturers aren’t required to prove their products’ safety or efficacy. Always scrutinize the ingredients and consult a healthcare professional for personalized advice.

Distinguishing Marketing Hype from Real Results

When it comes to nootropics, marketing hype can often blur the lines between the actual results and perceived benefits. Although Thesis Nootropics has received positive reviews and ratings, it’s essential to approach these with a degree of skepticism. Evaluate the product based on its ingredients and clinical research, rather than solely relying on testimonials.

Always consult a healthcare professional on the use of these supplements for any specific needs, and evaluate the ingredients and clinical research to differentiate between real results and marketing hype.

Customer Reviews

It’s crucial to consider the opinions of customers who have experienced Thesis Nootropics firsthand. In this section, we will delve into various customer reviews found on different platforms.

On the brand’s website, Thesis Nootropics has received a 4.4/5-star rating based on 7,956 reviews. This suggests that the majority of users found the product effective and worth investing in.

Some customers have also expressed concerns about the use of man-made ingredients—compared to more natural options

Customer reviews of Thesis Nootropics vary, and the product’s effectiveness may differ based on individual needs and preferences. While some users find it effective with positive ratings, others have concerns regarding its duration of benefits and ingredient selection.

What Do Experts Say?

Nootropics are compounds designed to enhance cognitive potential, improve state of well-being, and increase capabilities like reflexes and learning potential.

On Thesis website, you can see some testimonies coming from famous experts in the field: 

“I’ve been using Thesis for over a year now, and I can confidently say that their nootropics have been a total game changer for me” – Dr. Andrew Huberman (Neuroscientist and Professor of Neurobiology)

“I work with CEOs, celebrities, and other top performers in my practice. Thesis is what I recommend and take personally for focus and cognition. I even used it to help me nail my first TedX talk.” – Dr. Gabrielle Lyon (Functional Medicine and Nutritional Science) 

As cognitive enhancement is a complex area, the efficacy of Thesis Nootropics might not be universal for every user. Yet, the personalized approach they take to create nootropic blends might be a more fitting solution for many people

Monthly Subscription and Cost

To ensure the best value and experience with Thesis Nootropics products, you can opt for a monthly subscription. The subscription costs $ 79 per month , which is competitively priced within the market. With the subscription, you’ll receive a regular supply of nootropic blends (Energy, Motivation, or Clarity), so you can consistently maintain optimal cognitive performance.

When considering Thesis Nootropics as your cognitive enhancement solution, weigh your options regarding these blends and the subscription pricing. Ultimately, it’s an investment in your brain’s health and functionality.

Alternatives

While Thesis Nootropics offers a range of supplements for cognitive enhancement, there are many other nootropic brands on the market. Some popular alternatives include Mind Lab Pro, Qualia Mind, and Alpha Brain. It’s important to research different brands and compare ingredients before making a purchase.

Is It Worth It?

Based on our review of Thesis Nootropics, we believe that the brand offers high-quality supplements that can be effective for cognitive enhancement. However, the cost of some products may be prohibitive for some consumers. It’s important to weigh the potential benefits against the cost and consider alternative options.

Overall, Thesis Nootropics is a reputable brand that offers a variety of supplements for cognitive enhancement. While the cost of some products may be a concern for some consumers, the quality of the ingredients and the effectiveness of the supplements make it a worthwhile option to consider.

How long does it take for Thesis Nootropics supplements to take effect? 

The time it takes for Thesis Nootropics supplements to take effect can vary depending on the individual and the specific product. Some users report feeling the effects within 30 minutes to an hour, while others may take longer to notice a difference.

Are there any side effects associated with Thesis Nootropics supplements? 

While Thesis Nootropics supplements are generally considered safe, some users may experience side effects such as headaches, nausea, or difficulty sleeping. It’s important to start with a low dose and monitor any potential side effects.

Can I take Thesis Nootropics supplements with other medications or supplements? 

It’s important to consult with a medical professional before taking any new supplements or medications, including Thesis Nootropics. Some ingredients may interact with other medications or supplements, so it’s important to discuss any potential interactions with a healthcare provider.

• Choudhary, Dnyanraj, et al. “Efficacy and Safety of Ashwagandha (Withania Somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.” Journal of Dietary Supplements , vol. 14, no. 6, 21 Feb. 2017, pp. 599–612, https://doi.org/10.1080/19390211.2017.1284970 . 
• Kim, Hee-Yong, et al. “Phosphatidylserine in the Brain: Metabolism and Function.” Progress in Lipid Research , vol. 56, Oct. 2014, pp. 1–18, https://doi.org/10.1016/j.plipres.2014.06.002 . 
• Kimura, Kenta, et al. “L-Theanine Reduces Psychological and Physiological Stress Responses.” Biological Psychology , vol. 74, no. 1, Jan. 2007, pp. 39–45, https://doi.org/10.1016/j.biopsycho.2006.06.006 . 
• Li, I-Chen, et al. “Neurohealth Properties OfHericium ErinaceusMycelia Enriched with Erinacines.” Behavioural Neurology , vol. 2018, 2018, pp. 1–10, https://doi.org/10.1155/2018/5802634 . 
• Ma, Xiaohua, et al. “Phosphatidylserine, Inflammation, and Central Nervous System Diseases.” Frontiers in Aging Neuroscience , vol. 14, 3 Aug. 2022, https://doi.org/10.3389/fnagi.2022.975176 . 
• Malík, Matěj, and Pavel Tlustoš. “Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs.” Nutrients , vol. 14, no. 16, 1 Jan. 2022, p. 3367, www.mdpi.com/2072-6643/14/16/3367 , https://doi.org/10.3390/nu14163367 . 
• Mikulska, Paulina, et al. “Ashwagandha (Withania Somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review.” Pharmaceutics , vol. 15, no. 4, 24 Mar. 2023, p. 1057, https://doi.org/10.3390/pharmaceutics15041057 . 
• Nash, Kevin M., and Zahoor A. Shah. “Current Perspectives on the Beneficial Role of Ginkgo Biloba in Neurological and Cerebrovascular Disorders.” Integrative Medicine Insights , vol. 10, Jan. 2015, p. IMI.S25054, www.ncbi.nlm.nih.gov/pmc/articles/PMC4640423/ ,   https://doi.org/10.4137/imi.s25054 . Accessed 30 Apr. 2023.
• Rai, Sachchida Nand, et al. “Therapeutic Applications of Mushrooms and Their Biomolecules along with a Glimpse of in Silico Approach in Neurodegenerative Diseases.” Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie , vol. 137, 1 May 2021, p. 111377, https://pubmed.ncbi.nlm.nih.gov/33601145/ ,  https://doi.org/10.1016/j.biopha.2021.111377 . Accessed 30 Apr. 2023.
• Salekzamani, Shabnam, et al. “The Antioxidant Activity of Artichoke ( Cynara Scolymus ): A Systematic Review and Meta‐Analysis of Animal Studies.” Phytotherapy Research , vol. 33, no. 1, 22 Oct. 2018, pp. 55–71, https://doi.org/10.1002/ptr.6213 . Accessed 30 Apr. 2023.
• Sharif, Safia, et al. “The Use and Impact of Cognitive Enhancers among University Students: A Systematic Review.” Brain Sciences , vol. 11, no. 3, 10 Mar. 2021, p. 355, https://doi.org/10.3390/brainsci11030355 . 
• Tamura, Yasuhisa, et al. “Alpha-Glycerylphosphorylcholine Increases Motivation in Healthy Volunteers: A Single-Blind, Randomized, Placebo-Controlled Human Study.” Nutrients , vol. 13, no. 6, 18 June 2021, p. 2091, https://doi.org/10.3390/nu13062091 . 
• VanDusseldorp, Trisha A, et al. “Safety of Short-Term Supplementation with Methylliberine (Dynamine®) Alone and in Combination with TeaCrine® in Young Adults.” Nutrients , vol. 12, no. 3, 28 Feb. 2020, pp. 654–654, www.ncbi.nlm.nih.gov/pmc/articles/PMC7146520/ ,  https://doi.org/10.3390/nu12030654 . Accessed 30 Apr. 2023.
• Wang, Liwen, et al. “How Does the Tea L-Theanine Buffer Stress and Anxiety.” Food Science and Human Wellness , vol. 11, no. 3, 1 May 2022, pp. 467–475, www.sciencedirect.com/science/article/pii/S2213453021001324 ,  https://doi.org/10.1016/j.fshw.2021.12.004 . 
• Yoshikawa, Toshikazu, et al. “Ginkgo Biloba Leaf Extract: Review of Biological Actions and Clinical Applications.” Antioxidants & Redox Signaling , vol. 1, no. 4, Dec. 1999, pp. 469–480, https://doi.org/10.1089/ars.1999.1.4-469 . Accessed 30 Apr. 2023.

Next, check out some recent reviews you might find useful:

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Dorothy, a Registered Nutritionist-Dietitian, is currently pursuing a master’s degree in Public Health (MPH), with a major in Public Health Nutrition. Her enthusiasm for imparting knowledge about food, nutrition, and health is evident through her love for teaching university students. Apart from this, she has a keen interest in coffee, traveling, writing, cycling, running, cooking, and baking. Education: Silliman University Master of Public Health (MPH), Public Health Nutrition (2018-2022), Silliman University Bachelor of Science (BS), Nutrition and Dietetics (2010-2014)

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I Tried 4 Thesis Nootropic Blends (My 2024 Review)

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Thesis stands out in the wellness industry with its personalized nootropic supplements, designed to cater to the individual’s specific cognitive needs. It has been pushed by health and wellness celebrities, causing a wave of popularity.

Do Thesis nootropics live up to the hype?

• Variety Of Blends: Various nootropic blends based on individual brain chemistry, maximizing effectiveness for each user.
• Strong Advocacy and Support: Gained endorsements from notable wellness advocates and public figures, like Andrew Huberman, enhancing credibility.
• Limited Clinical Research: While the company plans clinical trials, the current scientific backing may be limited.
• Price: The ongoing cost of customized nootropics may be higher than standard off-the-shelf supplements or medications.
• Dependence on Self-Reporting: The effectiveness of blends relies partly on user feedback, which may not always be accurate or consistent.
• Many Underdosed Ingredients: As you’ll read below, many ingredients are dosed below what was used in human clinical trials.

Quick Verdict

Thesis has a range of suitable nootropic blends to cater to many needs.

However, our #1 nootropic of choice is NooCube. It’s designed for long-term brain changes, not just short-term boosts in mental performance.

What Is Thesis Nootropics?

Thesis Nootropics is a company specializing in customized cognitive performance products. It was founded by Dan Freed in 2017.

Freed’s personal challenges with focusing, which he faced from a young age, led him to discover nootropics.

This personal journey of transformation through nootropics inspired him to create Thesis, aiming to help others find the right combination of nootropic ingredients that work for them.

The company’s unique approach involves allowing customers to experiment with high-quality nootropic ingredients to maximize results systematically.

Thesis has gained popularity primarily through word-of-mouth and a strong focus on personalization.

The company has raised over $13.5 million in funding and is reportedly profitable with a robust growth trajectory.

Thesis has garnered support from health and wellness advocates like Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock.

Thesis Nootropics

Customized Blends For Cognitive Enhancement

Take the quiz and see which blends are right for you.

Thesis Nootropic Ingredients

Thesis have six unique blends designed to target various aspects of cognitive function. What’s similar between them is the option to include or exclude caffeine and L-theanine. The caffeine and l-theanine combination is the most potent instant nootropic, making each blend effective.

The caffeine L-theanine stack benefits physical and cognitive function. Some advantages include faster reaction time, faster visual processing speed, better working memory, increased awareness, and less tiredness and mental fatigue [1] [2] .

The research employs a 2:1 L-theanine to caffeine ratio, which Thesis has followed. Since this stack is available in every blend, I won’t include it in the ingredients breakdown below.

Thesis Clarity Blend

Alpha gpc (speculative).

Alpha GPC, a choline-containing phospholipid, improves cognitive function in neurological conditions like dementia [3] .

Research indicates it enhances memory and attention and may support brain health. Clinical trials show it can improve cognitive performance, especially when combined with other treatments like donepezil [4] .

It’s generally well-tolerated and safe. Alpha GPC increases acetylcholine levels in the brain, which is essential for memory and learning [5] .

It’s used both as a medicine and a nutritional supplement. Studies suggest Alpha GPC effectively boosts cognitive functions, particularly in adult-onset dementia disorders [6] .

Thesis Clarity Blend contains 500 mg, which is more than any other nootropic available.

Lions Mane Mushroom (Speculative)

The Lion’s Mane mushroom (Hericium erinaceus) includes chemicals that stimulate nerve growth factor (NGF) synthesis, which is necessary for nerve cell proliferation and differentiation [7] .

According to research, Lion’s Mane improves cognitive abilities, particularly memory and brain cell regeneration [8] .

It is renowned for its neuroprotective qualities, which may be effective in treating illnesses such as Alzheimer’s disease and cognitive impairment [9] .

Brain functioning, memory, and mood improvements have been linked to regular ingestion [10] .

While the mushroom does not directly improve cognitive skills, it does increase NGF, which improves brain health [11] . The dosage varies but is generally well-tolerated and has few negative effects.

Thesis Clarity contains 500 mg of Lions Mane, which may give a long-term nootropic effect.

Mycelium is typically avoided since the active chemicals are found in the primary mushroom. Jeff Chilton, a long-time mushroom researcher, discusses this in the podcast below:

Camellia Sinensis Tea Leaf (Speculative)

Camellia Sinensis, commonly known as tea, exhibits varying neuropharmacological effects based on the part of the plant used.

Seed extracts tend to be more stimulating, enhancing motor functions and showing potential as an antidepressant without causing drowsiness.

Leaf extracts, on the other hand, tend to produce a calming effect on the mind and mood. Both seeds and leaves have shown positive results in various tests assessing motor function and behavior in animal models [12] .

The study suggests these parts of the Camellia Sinensis plant have potential as cognitive enhancers, warranting further research, especially on seed extracts for their mode of action and possible new beneficial compounds.

I couldn’t find any human studies for this ingredient, so I can’t give you an efficacious dose range. But Thesis Clarity contains 278 mg of Camellia Sinensis Tea Leaf.

Dihydroxyflavone

Dihydroxyflavone research is all performed in rodents, so extrapolating to humans is rather challenging. 7,8-Dihydroxyflavone (7,8-DHF) is a compound that acts as an agonist for the TrkB receptor, which is associated with brain-derived neurotrophic factor (BDNF).

BDNF is crucial for neuronal survival and brain plasticity. Studies have shown that 7,8-DHF can improve memory and cognitive functions [13] .

It enhanced memory formation in healthy rats, and in Alzheimer’s disease mouse models, it improved spatial memory [14] .

Further, 7,8-DHF has been shown to counteract aging-related cognitive impairments in rats, improving spatial memory and synaptic plasticity in the hippocampus [15] .

This suggests that 7,8-DHF is a potential therapeutic agent for memory impairment and dementia, at least in rodents.

Thesis Energy Blend Ingredients

Citicoline is commonly mentioned in relation to memory enhancement. According to studies, 500 mg daily may improve episodic memory or the ability to recall personal experiences and specific events [16] .

According to other research, taking at least 500 mg of this supplement daily may provide cognitive benefits to healthy persons [17] .

The formulation of Thesis Energy Blend contains 300 mg of Citicoline. This dose may not achieve the full potential seen in studies proposing a higher dose.

Mango leaf extract, rich in the polyphenolic compound mangiferin, shows promise in neuropharmacology due to its anti-inflammatory, antioxidant, and antidiabetic properties.

Studies indicate its potential in treating central complications associated with metabolic disorders like type 2 diabetes, which are risk factors for Alzheimer’s disease and vascular dementia [18] .

In animal models, mango leaf extract has demonstrated effects on reducing brain inflammation and spontaneous bleeding and improving cognitive functions [19] .

These findings suggest its utility in addressing symptoms of neurodegenerative diseases and cognitive impairments [20] .

Thesis Energy contains 300 mg of mango leaf.

Theacrine is a purine alkaloid similar to caffeine, found in the Camellia Kucha plant, and often included in dietary supplements.

Studies show that it can increase energy, focus, and cognitive performance, similar to caffeine, but without habituation [21] .

Theacrine’s impact on cognitive performance and physical endurance has been researched in athletes, indicating possible benefits in reaction time and endurance [22] .

It may work well alone or in combination with caffeine to enhance cognitive function and physical performance [23] .

Theacrine appears to be a promising supplement for improving mental alertness and physical capacity. Bear in mind the manufacturers of Theacrine fund some of these studies.

Thesis Energy contains 100 mg of Theacrine, which tends to be less than the dose used in these studies, suggesting it may have a weaker effect.

N-Acetyl Cysteine

N-acetyl cysteine (NAC) is explored for its potential to improve cognitive functions in psychosis and bipolar disorder due to its antioxidant, neurogenesis, and anti-inflammatory properties.

Studies show N-acetyl cysteine can improve working memory in psychosis [24] . However, results in bipolar disorder didn’t show significant cognitive improvements [25] .

Research indicates potential benefits for Alzheimer’s disease by promoting cognitive health and countering oxidative stress [26] .

The effectiveness of N-acetyl cysteine in various cognitive disorders still requires more targeted, larger studies to confirm its benefits [27] .

N-acetyl cysteine’s role is promising but not yet firmly established in cognitive enhancement.

In human trials, it seems a 600 – 2000 mg dose is needed for cognitive benefits. Thesis Energy contains 500 mg, being potentially underdosed.

Indian Trumpet Tree

Indian Trumpet Tree is known as Oroxylum indicum. In a 12-week study, older adults with memory complaints took 500 mg of Oroxylum indicum extract twice daily [28] .

Compared to a placebo, this supplementation led to improvements in episodic memory and numeric working memory. It also accelerated learning in location tasks.

However, there were no significant changes in other cognitive tests or overall cognitive and memory skills.

The study suggests that Oroxylum indicum, while well-tolerated, may primarily enhance specific memory functions.

Its potential effects could be linked to its antioxidant and anti-inflammatory properties and interactions with neurotransmitters like dopamine and GABA.

This is the only human study on the Indian Trumpet Tree, so more research is needed to fully understand its impact on cognitive health. Thesis Energy only contains 100 mg of this, making it potentially underdosed.

L-tyrosine, an amino acid, has been shown to increase dopamine levels in the brain. L-tyrosine supplementation has improved cognitive regulation, particularly in mentally demanding settings [29] .

It is especially helpful in improving cognitive flexibility, which is impacted by dopamine.

While L-Tyrosine’s promise for treating clinical problems and improving physical activity is limited, it is useful in stressful or cognitively taxing situations.

It has the greatest cognitive benefits when neurotransmitter activity is intact, but dopamine and norepinephrine levels are momentarily decreased [30] .

According to research, optimal doses for cognitive improvement begin at a minimum of 2 grams. That is more than six times the dose in Thesis Energy.

Thesis Creativity Blend Ingredients

Thesis Creativity contains 150 mg of Alpha GPC, yet their Clarity Blend contains 500 mg. I’m not sure why there is a large discrepancy, especially when 500 mg is likely a more efficacious dose.

Agmatine Sulfate

Currently, agmatine sulfate has only been tested in rodents. It is a central nervous system (CNS) neurotransmitter/neuromodulator that has been studied for its potential effects on stress-related conditions like depression, anxiety, and cognitive performance.

Research suggests that agmatine can have antidepressant and anxiolytic (anxiety-reducing) effects, possibly related to its influence on the nitric oxide pathway [31] .

It may reduce oxidative stress and corticosterone levels while increasing brain-derived neurotrophic factor (BDNF), which is beneficial for brain health.

Agmatine sulfate has been shown to be safe and well-tolerated in animal studies, with oral administration effectively increasing its levels in the brain [32] .

This indicates potential for therapeutic use in neurological disorders, though more research is needed to fully understand its effects and mechanisms.

Thesis Creativity contains 250 mg. In these studies, patients were administered 15-600 mg per kg, which is a much higher dose.

Panax Ginseng

Panax ginseng is available in two varieties: white ginseng and red ginseng. It has vasorelaxant and moderately hypotensive effects on nitric oxide generation in the body [33] .

It increases antioxidant enzyme activity and may prevent oxidative damage associated with aging in rats [34] .

Ginseng has shown promise in boosting memory, particularly in age-related cognitive decline, as well as in improving mental and physical resilience, reducing fatigue, and assisting the body in adapting to stress [35] .

Daily doses of 200 mg extract or 0.5 to 2 g dry root are recommended. It is not suggested for persons with acute asthma or hypertension because it may cause overstimulation and elevate blood pressure in excessive dosages.

Thesis Creativity has an effective dose of 200 mg, which may provide you with these mental performance benefits.

Ashwagandha Root

Ashwagandha is a traditional herbal remedy used to improve various health conditions. Animal studies have shown that it can increase blood cell counts, which might enhance aerobic capacity [36] .

It also demonstrates the potential to reduce oxidative stress and lipid peroxidation, which could be beneficial in treating disorders like tardive dyskinesia [37] .

Additionally, Ashwagandha has shown nootropic effects and might be useful in treating Alzheimer’s disease [38] . Recommended dosages range from 6 to 10 grams of ground roots or 100 to 1250 mg of extract daily [39] [40] .

It’s generally safe but should be used cautiously, especially in cases of hyperthyroidism or pregnancy. High doses can have sedative effects and may cause gastrointestinal issues.

Thesis Creativity contains 300 mg of Ashwagandha, which is within the recommended range for cognitive benefits.

Sceletium Tortuosum

Sceletium tortuosum, also known as Kanna, is traditionally used for its mood-enhancing properties. It’s been studied for its potential in treating cognitive and neurodegenerative disorders like Alzheimer’s and Parkinson’s [41] .

Research suggests its constituents could target enzymes and receptors relevant to these diseases, offering neuroprotective benefits like antioxidant activity [42] .

Additionally, Sceletium Tortuosum is known for its antidepressant and anxiolytic effects, promoting relaxation and well-being, which could be beneficial in managing stress, anxiety, and depression [43] .

The plant’s bioactive alkaloids are also being explored for commercial medicinal use.

The 25 mg dose in Thesis Creativity is the same as used within the human trials.

Thesis Motivation Blend Ingredients

L-phenylalanine.

L-phenylalanine is a vital amino acid and has been explored for its potential benefits in managing conditions like attention deficit disorder and depression.

In studies, doses of up to 1200 mg showed initial improvements in mood and attention in individuals with attention deficit disorder, but tolerance developed over 2-4 months [44] .

In another study involving depressed patients, a dosage range of 75–200 mg/day for 20 days led to significant improvements in 12 out of 20 patients [45] .

However, the effectiveness and safety of L-phenylalanine can vary, and it is used in the treatment of various conditions, including depression and arthritis, and even as part of addiction recovery [46] .

Thesis Motivation has a 500 mg dose, which may provide some of these benefits. Will it improve motivation? I’m not sure.

Methylliberine

Methylliberine is a purine alkaloid explored for its cognitive and mood-enhancing effects. Studies have shown it can improve concentration, motivation, and mood, especially when combined with caffeine.

Methylliberine also appears to positively affect energy levels and well-being without significantly impacting vital signs like heart rate and blood pressure [47] .

These findings suggest its potential as a nootropic supplement, particularly for enhancing cognitive function and mood in various contexts, such as gaming or in tactical scenarios [48] [49] .

However, it’s essential to consider the dosage and combination with other compounds like caffeine for optimal effects.

The 100 mg dose in Thesis Motivation aligns with the current research.

Vitamin B12 (Speculative)

Vitamin B12 is essential for cognitive health and may be linked to neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Low levels of B12 are associated with cognitive impairment, but supplementation is only shown to be effective in improving cognition in cases of existing B12 deficiency [50] .

There is limited evidence that increasing B12 levels benefits people without B12 deficiency [51] .

B12’s impact on cognitive health may involve multiple mechanisms, including brain volume and function [52] . However, more extensive research is needed to fully understand its effects and potential as a cognitive enhancer.

Thesis Motivation contains 1000mcg. The research states that it may have no effect if you’re not Vitamin B12 deficient.

Forskolin (Speculative)

Forskolin has only been studied in rodents regarding cognitive function. Forskolin is an herbal extract that shows the potential to improve memory and reduce Alzheimer’s disease symptoms.

In studies, it restored nest-building and social behaviors in mice with Alzheimer-like symptoms, reduced amyloid plaque deposition, and regulated brain inflammation [53] .

Forskolin also influences memory and tau protein phosphorylation in the brain, which is relevant in Alzheimer’s [54] .

Additionally, forskolin has shown protective effects against Huntington’s disease-like neurodegeneration in rats by improving learning and memory and reducing oxidative stress [55] .

These findings indicate forskolin’s potential as a neuroprotective agent for certain neurological conditions, at least in rodents.

I’m skeptical whether 250 mg of Forskolin in Thesis Motivation will help you “feel” more motivated.

Artichoke (Speculative)

Artichoke extract is known for its prebiotic properties and promotes probiotic bacteria growth in the gut, potentially benefiting cognitive functions in mice [56] .

In elderly individuals with mild cognitive impairment, combining artichoke extract and aerobic training improved cognitive status and reduced blood glucose and insulin resistance [57] .

Artichoke varieties Spinoso Sardo and Romanesco Siciliano demonstrated antioxidant properties and potential protective effects against cardiovascular and neurodegenerative disorders, with Romanesco Siciliano showing higher antioxidant power [58] .

The 450 mg dose is well under the dose used in these studies.

Thesis Confidence Blend Ingredients

Saffron (speculative).

Saffron is traditionally used in herbal medicine and shows promise in improving cognitive function in individuals with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) [59] .

Research indicates that saffron’s effectiveness is comparable to common drugs used for these conditions without increasing side effects. It’s also well-tolerated in cognitively normal individuals [60] .

However, most current studies have a high risk of bias. More comprehensive, low-bias clinical trials are needed to confirm saffron’s potential as a treatment for cognitive impairments like AD and MCI.

All of the research used 30 mg of saffron daily. Thesis Confidence has 28 mg, and I’m unsure why they formulated it without the extra 2 mg.

Magnesium Bisglycinate

Magnesium is essential for brain functions and has been researched for its potential cognitive benefits. Magnesium is particularly effective in increasing brain magnesium levels and has shown promise in improving memory and cognition in healthy adults [61] .

However, its role in anxiety and mood disorders is less clear [62] .

Studies indicate magnesium may help reduce symptoms of depression, but results are not consistent across all mental health conditions [63] .

Further research is needed to conclusively establish magnesium’s effectiveness and appropriate use as a therapeutic supplement in various psychiatric and cognitive disorders [64] .

500 mg of magnesium may help if you’re deficient, but there’s no clear benefit to making you more confident.

Sage (Speculative)

Sage is known as Salvia and has been traditionally known to enhance memory. A recent study supports this, showing that acute ingestion of sage oil can significantly improve immediate word recall in healthy young adults [65] .

This suggests that sage may positively influence cognitive functions like memory, potentially due to its acetylcholinesterase inhibition activity in the brain.

However, this has not been replicated.

While historically used for various mental disorders, such as depression and age-related memory loss, contemporary research is needed to fully understand its benefits and potential as a cognitive enhancer.

Regardless of the 333 mg dose, this is one of the more speculative ingredients in all Thesis blends.

Sceletium Tortuosum (Speculative)

As mentioned in the Creativity Blend, Sceletium Tortuosum is known for its mood-enhancing properties. It is the same dose of 25 mg, which is used in human trials.

Magnolia Bark (Speculative)

Magnolia officinalis is commonly used in traditional medicine for mental disorders like anxiety and depression and shows potential as a nootropic supplement.

Studies have demonstrated that its ethanol extract can improve cognitive function and memory in stress-induced situations. It also exhibits anxiolytic properties, reducing anxiety-related behaviors in rats [66] .

The extract’s effectiveness is also evident in lowering stress-induced increases in corticosterone and tyrosine hydroxylase levels.

Moreover, Magnolia officinalis, especially its component honokiol, has neuroprotective effects and can regulate mood disorders by modulating GABA and CB1 receptors in rats [67] .

These are rodent studies, so it’s impossible to extrapolate to humans. Regardless, it’s included based on the mechanistic data with the theory of doing the same thing in humans with the 10 mg dose.

Ashwagandha Leaf & Root

The 120 mg of root and leaf ashwagandha may be enough to have a nootropic effect as the extract dose is between 100-1200 mg, as stated in the Creativity Blend section. However, this is root and leaf, and the main benefits are derived from the root.

Thesis Logic Blend Ingredients

Ginko biloba.

Ginkgo biloba is extracted from the leaves and fruit to improve cognitive function. Its compounds include antioxidants, enhance blood flow, and have anti-inflammatory properties.

Ginkgo biloba extract has been shown in animal studies to help with chronic brain difficulties by modifying inflammatory mediators and the cholinergic system [68] .

It has been shown in clinical trials to improve working memory and processing speed [69] . However, its usefulness in healthy people under the age of 60 is debatable [70] .

Typical daily doses vary from 120 to 300 mg. Although side effects are uncommon, they can include stomach irritation and headaches, which may cause blood to thin, affecting people on certain drugs.

Thesis Logic contains 160 mg of Ginkgo Biloba, which is within the recommended dosage range.

Theobromine

Theobromine is a compound found in chocolate and has been studied for its potential cognitive effects.

Research indicates that theobromine might have a lesser immediate nootropic effect compared to caffeine but could have neuroprotective benefits with long-term consumption, possibly reducing Alzheimer’s disease-related pathology [71] .

Further studies are needed to fully understand its impact on cognition.

Additionally, theobromine’s effects on mood and vigilance appear to be different from caffeine, with some studies suggesting it might not significantly influence these aspects in nutritionally relevant doses [72] .

However, combining theobromine with caffeine could modify its effects, potentially offering cognitive and mood benefits without significant blood pressure increases [73] .

More research is required to confirm theobromine’s cognitive and mood-related effects.

Thesis Logic contains 100 mg of theobromine, but it seems doses greater than 400 mg are needed to enhance cognition.

Phosphatidylserine

Phosphatidylserine is essential for proper brain function. Phosphatidylserine has been proven to be critical for maintaining nerve cell membranes and myelin, which is required for successful neurotransmission [74] .

Phosphatidylserine can help reverse cognitive loss as the brain ages by boosting cognitive activities such as memory formation, learning, concentration, and problem-solving [75] .

It is well absorbed in humans and crosses the blood-brain barrier.

Supplements containing phosphatidylserine have been shown to increase cognitive functions and are generally well-tolerated, with dosages ranging from 100 to 800 mg per day advised for cognitive support [76] [77] .

Thesis Logic contains 400 mg of phosphatidylserine, which may provide you with these cognitive-enhancing effects.

High DHA Algae

DHA is a vital component of neuronal membranes and plays an important role in brain health and cognitive function.

Adult cognitive abilities are improved by DHA consumption, especially when paired with eicosapentaenoic acid (EPA) [78] .

This impact is most noticeable in older people who have mild memory problems. Higher DHA and EPA doses (above 1 g per day) have been associated with better episodic memory.

Observational studies also show a link between DHA/EPA intake and memory performance in the elderly. DHA, both alone and in combination with EPA, improves memory in the elderly.

Thesis Logic contains 200 mg of DHA, suggesting insufficient DHA to provide a benefit.

Triacetyluridine (Speculative)

Triacetyluridine is being explored as a potential treatment for bipolar depression. In a study involving eleven patients with bipolar depression, high doses of triacetyluridine (up to 18 g per day) were administered over 6 weeks [79] .

The study measured the effects on depression symptoms using the Montgomery-Asberg Depression Rating Scale (MADRS) and evaluated cellular bioenergetics using phosphorus magnetic resonance spectroscopic imaging (P-MRSI).

Results indicated significant early improvement in depression symptoms.

Additionally, triacetyluridine responders showed notable differences in pH changes from baseline, suggesting triacetyluridine may improve mitochondrial function and reduce symptoms of depression.

Thesis Logic has 30 mg of triacetyluridine, which is well below the dose used in this study.

Bacopa Monnieri

Bacopa monnieri is a traditional plant that has been shown to improve cognitive performance, particularly memory.

Bacopa extract, namely bacosides A and B, has been demonstrated in studies to increase memory formation, recall, and cognitive function [80] .

It has neuroprotective properties and is used to treat cognitive dysfunctions such as Alzheimer’s disease.

Adults should take between 200 and 400 mg each day. Bacopa is generally well accepted, with only rare reports of mild drowsiness or stomach difficulties.

Clinical trials show that older people have better memory, attention, mood, and overall cognitive ability [81] [82] [83] . More research is needed, however, to thoroughly grasp its usefulness across many cognitive domains.

Thesis Logic contains 320 mg of Bacopa, giving you the efficacious dose to feel these benefits.

Thesis Nootropics Price

Thesis has two options: one time purchase or a subscription. Here’s how the prices break down:

• Subscription = $79
• One Time Purchase = $119

This is regardless of whether you purchase a personalized starter kit or build your own box.

You can’t buy them individually either. You must purchase 4 boxes. When building your own, you can choose if you want 4 of the same blend or mix and match.

They want you to try each blend for a week as part of the starter kit (there’s only a week’s worth of each blend in each container) to see which you like best.

Thesis has positioned itself as the most expensive nootropic available by adding the personalized element.

Is Thesis Nootropics Really Personalized?

I went through the initial quiz to see how they “personalize” their nootropic stack.

Here is what they recommended me:

Look, I get the marketing angle. In no way is this a truly personalized nootropic product. It’d be nearly impossible to create custom formulations for every unique individual.

However, the fact they have multiple blends means people can experiment to find which works best for them.

I will say, though, if you choose the caffeine options, every blend will work. Many of the ingredients used in these blends are speculative and only based on animal research, with many being underdosed.

Benefits Of Thesis Nootropics

Multiple blends for different purposes.

To be honest, this benefit is more of a marketing tactic. However, some people may find certain blends jive well with them over others, giving you options within the same brand.

Further, Thesis claims the ingredients in each formulation work synergistically. There’s no research to back that claim, but at least know there are no negative side effects from their interaction.

Options For Stimulants Or Not

You can choose whether or not you want stimulants within your Thesis Blends. Every blend will provide similar benefits if you add the caffeine and L-theanine nootropic stack, which is the most potent synergistic brain booster.

However, if you’re already a coffee addict or plan to take Thesis in the evening, having no stimulants is the better option.

My Experience With Thesis

Based on my quiz, I was recommended Thesis Clarity, Logic, Motivation, and Confidence Blends. I tried each for a week to see if one stood out. I took them without caffeine as they all work if you have the caffeine L-theanine stack.

I have to say the Confidence and Motivation Blends did absolutely nothing for me. I didn’t “feel” any brain-boosting effects or feel more confident or motivated.

I felt the Logic and Clarity Blends had small positive effects when concentrating on mentally demanding tasks like writing, coaching, or podcasting.

If I were to continue taking Thesis, I’d opt for either of these two blends.

Who Is Thesis For?

Busy working professionals.

Thesis Nootropics are ideal for busy professionals facing demanding schedules and high-stress environments. These blends can help enhance focus, improve decision-making, and increase productivity.

They are designed to support sustained mental energy throughout the day, enabling professionals to manage their workload more effectively without the usual mental fatigue.

Creative Artists

For creative artists, Thesis offers blends that stimulate creativity and enhance divergent thinking. These nootropics can aid in breaking through creative blocks, fostering innovative thinking, and maintaining a heightened state of inspiration.

They are particularly beneficial for artists seeking longer periods of creative flow and those seeking fresh perspectives.

Students can significantly benefit from Thesis Nootropics, especially during intense studying or when facing challenging academic projects.

The blends are formulated to enhance memory retention, improve concentration, and boost learning capabilities. This makes them a valuable tool for students who need to absorb and retain large amounts of information and perform well in academic assessments.

Gamers find Thesis Nootropics beneficial for improving their gaming performance. The blends can enhance reaction times, increase focus, and improve strategic thinking skills.

They are particularly useful during long gaming sessions, helping gamers stay alert and responsive, which is crucial in competitive gaming scenarios.

Coffee Haters

Thesis Nootropics provides an excellent alternative for those who dislike coffee or want to avoid caffeine jitters.

These blends offer a way to boost mental energy and alertness without relying on caffeine. This makes them ideal for individuals sensitive to caffeine or those seeking to reduce caffeine intake while maintaining high cognitive function.

User Testimonials And Reviews

You can’t access the review database on the Thesis website, so I did some digging to find user reviews. Here’s a couple of positive reviews:

“I must admit that during the weeks that I consistently take them, I perform better & I generally feel better just knowing I’ve ingested something intended to positively alter my natural brain state. Minor tasks/chores no longer seem as daunting and I get this underlying kick to complete my work well.” – ParsnipExtreme2502 (Reddit)

“I didn’t find Weeks 1 and 4 to do anything for me, but Weeks 2 and 3 really helped avoid the post-lunch, post-work slumps I tend to get now that I’ve been working from home; Energy is especially useful for days when I haven’t gotten enough sleep the night before.” – leftylucy88 (Reddit)

I can’t find many negative reviews other than potential side effects like migraines, which can be caused by many different factors.

Thesis Side Effects

Side effects are rare from the ingredients in these blends. I personally didn’t have any adverse reactions to the four blends I tried. However, like any supplement, they may have potential side effects.

Consult with a healthcare provider before starting any nootropic regimen, especially if they have pre-existing health conditions, are pregnant or breastfeeding, or are taking other medications.

Thesis Alternatives

If Thesis Nootropics isn’t quite the right match for you or you’re just curious about other products, here are some alternatives I’ve tried and can provide an insider’s look into.

SAP Nutra nootropic Nooceptin improves memory, concentration, and cognitive performance without stimulants. It offers gradual brain health gains.

It improves memory and focus and provides a prolonged boost without a caffeine crash. Students, gamers, professionals, and seniors should use Nooceptin to boost cognition.

This brain supplement contains Lion’s Mane Extract, Citicoline, Rhodiola Rosea Extract, L-Theanine, Bacopa Monnieri, Ginkgo Biloba, and Panax Ginseng.

Some of these compounds have been shown to be useful, but others are experimental. Nooceptin, a non-stimulant method for long-term cognitive enhancement, usually works after 7-14 days.

Despite the risk of underdosed components and increased cost, Nooceptin may provide a stimulant-free cognitive boost.

Read more in our Nooceptin review .

Mind Lab Pro

Mind Lab Pro is a popular nootropic that has gained appeal as a result of its alleged cognitive benefits.

Pure substances are used in its formulation, which is intended to improve mental clarity and attention. It is stimulant-free, making it an excellent choice for anyone seeking a well-rounded routine.

Its unique combination of 11 research-backed components distinguishes it from competitors in the brain health supplement sector.

These compounds were carefully chosen to help cognitive processes like memory, focus, mental clarity, mood, and cognitive processing speed.

Despite some criticism about the quantity of specific substances and the need for more scientific data, Mind Lab Pro has earned worldwide recognition for its ability to improve cognitive performance in professionals, students, the elderly, and athletes.

Our Mind Lab Pro review goes into great detail.

Braini distinguishes itself by being stimulant-free, providing long-term results, and having a short ingredient list focusing on long-term cognitive gains. It does not, however, deliver the immediate euphoric boost that some users may expect from a brain supplement.

Peptylin, a silk protein peptide with neuroprotective effects and potential benefits for executive function; NeurXcel, which is rich in omega fatty acids; and Wild Canadian Blueberry extract, which is known for its antioxidant characteristics and cognitive support, are all key ingredients in Braini.

Braini is backed by clinical trials, a 60-day money-back guarantee, and a 30-day challenge to scientifically quantify changes in brain function.

Our Braini review contains an in-depth breakdown.

Vyvamind is a nootropic supplement containing caffeine and L-theanine to help focus and improve cognitive performance. Users claim increased focus, vitality, and cognitive abilities without big crashes.

Vyvamind’s formulation, which contains less L-tyrosine and citicoline than some studies suggest, is intended to supplement the major nootropic duo of caffeine and L-theanine.

This combination is well-known for boosting concentration and cognitive function. The supplement is touted as a non-stimulant alternative, appealing to clients seeking a more natural and less intensive approach to cognitive growth.

Vyvamind is suitable for coffee-averse people, busy professionals who require a focus boost, and students during study sessions.

Our Vyvamind review goes into great detail.

Because of its purported fast cognitive effects, NooCube is a popular brain-boosting product. NooCube contains ingredients such as Bacopa Monnieri, L-Tyrosine, and L-Theanine.

These are well-known for their mental health advantages. Several compounds, such as Huperzine-A and Alpha GPC, remain speculative without additional investigation.

NooCube is intended to improve cognition and alertness without using stimulants, and the amounts of each ingredient are clearly labeled.

Because it gives different cognitive benefits without the jittery side effects associated with caffeine, NooCube is especially good for working professionals, students, elders, gamers, and combat athletes.

Our detailed analysis can be found in our NooCube review .

Frequently Asked Questions

What is thesis nootropic and what does it do.

Thesis Nootropic is a personalized supplement formulated to enhance cognitive functions. Users can expect improvements in focus, reduction in procrastination, stress management, and memory recall, depending on which blend you choose.

Does Thesis Work Like Adderall?

Thesis Nootropics and Adderall are used to enhance cognitive functions, but they are fundamentally different. Adderall is primarily prescribed for treating Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.

Adderall is an amphetamine, classified as a controlled substance due to its strong stimulating effects and potential for abuse and dependency.

Thesis Nootropics are dietary supplements designed to enhance healthy individuals’ cognitive functions, such as memory, focus, and mental clarity. They are not intended to treat medical conditions like ADHD.

How Long Does It Take Thesis Nootropics To Work?

If you have the caffeine version, within 30 minutes. You may feel the non-stimulant blends kicking in just as quickly, but they won’t be as pronounced. Sometimes, they can take multiple weeks to feel them working.

I’ve taken a deep dive into the world of nootropics and shared my firsthand experience with Thesis Nootropic’s various blends. While the personalization is nothing more than a marketing tactic, the different blends are a nice touch for those who want to experiment with different ingredients.

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Table of Contents

About Thesis Nootropics

Hands up if you guzzle five coffees a day to stay awake, have tried all the supplements in the book desperate to improve your headspace, and aren’t interested in prescribed medications. Designed to increase focus , Thesis nootropics might be for you. 

Thesis offers a customized blend of ingredients designed to optimize your cognitive function , with personalized details that tackle your specific needs. Nootropics boost brain performance in the same way a stimulant would, without the common negative effects. 

A study published in the Journal of Alzheimer’s Disease found that nootropics may help improve cognitive function in people with Alzheimer’s disease.

Interested in finding out more about the brand and how it works? Leaf through our Thesis Nootropics review. We’ll be your guide through the company and the process, as well as details on the treatments, highlights from customer reviews, answers to important FAQs, and more, to help you decide if it’s worth the try.

Pros and Cons

• Multiple cognitive benefits: Thesis Nootropics offers a variety of blends that cater to multiple aspects of cognitive function.
• Long-term effects: On top of short term benefits for daily life, Thesis nootropics ingredients are designed to impact the brain in the long-term.
• Personalized recommendations: Thesis Nootropics makes personalized recommendations based on your goals and unique brain chemistry.
• Potential side effects: The most common side effects to watch out for when you start taking Thesis Nootropics include heartburn, headaches, confusion, dizziness, loss of appetite, and digestive issues.
• Need to stop taking if issues arise: If you experience a headache or an upset stomach that won’t go away while taking their nootropics, Thesis recommends that you stop taking them.

What is Thesis Nootropics?

Nootropics are nutrient compounds and substances that are known to improve brain performance , such as caffeine and creatine. They help with issues that affect motivation, creativity, mood, memory, focus, and cognitive processing.

Nootropics are the ideal addition to an already healthy lifestyle that consists of exercise, proper nutrition, and enjoyable activities.  Thesis nootropics are carefully formulated to target specific needs, ranging from energy to creativity. The brand focuses on safety, ensuring that all supplements adhere to FDA guidelines and go through multiple clinical trials. 

How Thesis Nootropics Works

With all that being said, you may be wondering how Thesis provides users with an option that is specific to their needs. Fortunately, the process is simple and hassle free. Here’s how it works:

• Take the Thesis nootropics quiz
• Answer questions about your basic information
• Receive personalized recommendations 
• Get your starter kit for $120 , or $79 monthly when you subscribe 

After that, you’ll select one formula to take each week, taking one day off in between each different option. You’ll also track your results in the daily journal over the month to see how they affect your daily life. 

From there, it operates as a subscription service. Users will be able to optimize their next shipment by telling the brand which formulas worked best.

If you don’t like any of the blends in your box, let the company know and they’ll switch it for something that’s a better fit for your lifestyle, genetics, and goals.

Thesis Nootropics Ingredients

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties. Here are some of the key ingredients in Thesis Nootropics:

• Cognizin (Citicoline) : Cognizin is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• L-Theanine : L-Theanine is an amino acid that is found in green tea, and is known for its ability to promote relaxation and reduce stress and anxiety.
• Lion’s Mane Mushroom : Lion’s Mane Mushroom is a type of medicinal mushroom that is believed to have cognitive-boosting properties, including improved memory and focus.
• Rhodiola Rosea : Rhodiola Rosea is an adaptogenic herb that is known for its ability to reduce stress and fatigue, and improve mental clarity and cognitive function.
• Ashwagandha : Ashwagandha is an adaptogenic herb that is known for its ability to reduce stress and anxiety, and improve memory and cognitive function.
• Phosphatidylserine : Phosphatidylserine is a type of phospholipid that is found in high concentrations in the brain, and is believed to support cognitive function, including memory and focus³
• Alpha-GPC : Alpha-GPC is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• TAU (uridine): TAU is a blend of uridine, choline, and DHA, which is believed to support brain health and cognitive function.
• Artichoke extract : Artichoke extract is believed to enhance cognitive function by increasing levels of acetylcholine, a neurotransmitter that is important for memory and learning.
• Dynamine : Dynamine is a type of alkaloid that is believed to enhance cognitive function by increasing levels of dopamine, a neurotransmitter that is important for mood and motivation.

Overall, the ingredients in Thesis Nootropics are carefully chosen for their cognitive-boosting properties, and are designed to work together to enhance overall brain health and cognitive function.

Thesis Nootropics Health Benefits

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties, and offer numerous health benefits. Here are some of the health benefits of Thesis Nootropics:

• Increased cognitive energy : One of the key benefits of Thesis Nootropics is increased cognitive energy, which can help improve productivity, mental alertness, and motivation, as it contains cognizin .
• Enhanced mental clarity : Another benefit of Thesis Nootropics is enhanced mental clarity,given from Lion’s Mane Mushroom which can help reduce brain fog and improve focus.
• Improved memory and learning abilities : Thesis Nootropics contains ingredients that are believed to improve memory and learning abilities, like Phosphatidylserine , which can help users retain information more effectively.
• Elevated mood : Thesis Nootropics may help elevate mood and reduce symptoms of anxiety and depression, thanks to ingredients like L-Theanine and Ashwagandha .
• Lowered stress levels : The adaptogenic herbs in Thesis Nootropics, such as Rhodiola Rosea and Ashwagandha , are known for their ability to lower stress levels and promote relaxation.
• Boosted focus : Thesis Nootropics contains ingredients like Alpha-GPC and Artichoke extract , which are believed to boost focus and concentration.

While Thesis Nootropics offers numerous health benefits, it’s important to note that the long-term effects of nootropics are not yet fully understood and more research is needed.

3 Thesis Nootropics Bestsellers

Thesis energy review.

If you’re constantly struggling to keep up with the demands of your busy life, it might be time to try a natural energy booster like Thesis Energy. This powerful nootropic blend is specifically designed to increase energy, overcome fatigue, and build mental stamina.

Thesis Energy is caffeine-free, making it a great option for those who are sensitive to caffeine or looking for a natural alternative to traditional energy drinks. The Energy formulation is designed to help improve focus and mental clarity, increase cognitive energy, and reduce fatigue. Whether you’re facing a busy day at work, recovering after a night of poor sleep, or gearing up for an intense workout, Thesis Energy can help you power through.

Each ingredient in Thesis Energy is carefully chosen for its energy-boosting properties. The specific ingredients can vary depending on your needs, but they work together to help increase energy, improve mental clarity, and reduce fatigue.

To get the most out of Thesis Energy, take it every morning on an empty stomach. You can also take it again after lunch if you need an extra boost. It’s designed to help you tackle busy, hectic days, recover from poor sleep, and power through intense workouts.

If you’re tired of relying on coffee and energy drinks to get through the day, it might be time to give Thesis Energy a try. Check availability and start boosting your energy naturally today!

Thesis Creativity

If you’re someone who struggles with creativity or finds yourself feeling stuck in your creative endeavors, Thesis Creativity may be worth considering. This nootropic supplement is designed to help spark inspiration, enhance verbal fluency, and boost confidence in your own great ideas.

So what’s in Thesis Creativity? The ingredients may vary depending on your specific needs, but these ingredients work together to support stress management, memory function, mood regulation, and energy production.

By supporting stress management, memory function, and mood regulation, Thesis Creativity can help free up mental space for more creative thinking. Additionally, the caffeine and L-theanine combo can provide a boost of energy and focus without the jitters and crash that can come with caffeine alone.

To get the most out of Thesis Creativity, it is recommended to take it every morning on an empty stomach and again after lunch if you need an extra boost. This nootropic blend is particularly helpful for brainstorming and creative thinking, writing and creative projects, and public speaking and social situations.

As with any nootropic supplement, it’s important to note that the long-term effects of Thesis Creativity are not yet fully understood and more research is needed. It’s always a good idea to speak with a healthcare professional before adding any new supplements to your routine.

In summary, if you’re looking for a little extra help in the creativity department, Thesis Creativity may be a valuable addition to your nootropic lineup. Its unique blend of ingredients can help support mental clarity, mood regulation, and energy production, making it a valuable tool for any creative individual.

Thesis Logic

If you’ve been having trouble with your memory lately, such as forgetting what you had for lunch yesterday or struggling to recall common words, then Thesis Logic may be just what you need. This formula is designed to help enhance your processing speed, boost your memory, and deepen your thinking.

Thesis Logic is caffeine-free, making it a great option for those who are sensitive to caffeine. The formula is ideal for use during deep, focused work, complex problem-solving, research projects, and completing tedious tasks.

Taking Thesis Logic is easy – simply take it every morning on an empty stomach, and take it again after lunch if you need an extra boost. By incorporating Thesis Logic into your daily routine, you may notice improvements in your cognitive function and overall mental performance.

Who Is Thesis Nootropics For? 

Thesis nootropics are designed for a number of different specific needs, including anyone who wants to focus better, have more energy, and maintain mental clarity. All in all, the products are specifically formulated to improve day to day life and target your specific needs .

Thesis Nootropics Side Effects

While Thesis nootropics are designed to enhance cognitive performance and provide a range of benefits, it’s important to be aware of the potential side effects that can occur. As with any supplement, individual reactions can vary, and some people may experience side effects while others may not.

Some of the potential side effects of Thesis nootropics include:

• Insomnia : Some nootropics contain caffeine or other stimulants that can disrupt sleep patterns and lead to difficulty falling asleep or staying asleep.
• Blurry vision : Certain nootropics, such as those containing alpha GPC, have been linked to temporary blurry vision.
• High blood pressure : Stimulant-based nootropics can increase blood pressure, which can be dangerous for people with hypertension or other heart conditions.
• Fast heart rate : Similarly, stimulants can also increase heart rate, leading to palpitations or a rapid pulse.
• Circulation problem s: Certain nootropics, such as vinpocetine, can affect blood flow and circulation, leading to issues like dizziness, nausea, or headaches.
• Addiction : Some nootropics, such as those containing racetams, have been associated with the potential for addiction or dependence if used long-term.

It’s important to remember that not all nootropics will produce these side effects, and the severity of any reactions will depend on individual factors such as dosage, duration of use, and underlying health conditions. However, it’s always wise to discuss any potential risks with a healthcare professional before starting any new supplement regimen.

Additionally, it’s important to follow dosage instructions carefully and not to exceed recommended amounts, as this can increase the risk of side effects. By being mindful of potential risks and using nootropics responsibly, users can reap the benefits of these supplements without experiencing adverse effects.

Thesis Nootropics Reviews: What Do Customers Think?

At this point in our Thesis nootropics review, it’s time to turn to what customers are saying. So, we sourced testimonials from the brand’s website, Reddit, and ZenMasterWellness. And spoiler alert, the Thesis nootropics reviews we came across have nothing but good things to say.

On takethesis.com , the brand earns 4.4/5 stars out of 7,956 reviews. One patron describes their particular blend as the perfect alternative to prescription meds :

“ I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work .”

On Reddit, many reviewers share similar sentiments about how effective the products are. One buyer shares that they tried tons of different nootropics on the market, and Thesis stands out amongst the crowd . 

On ZenMasterWellness, one reviewer states that their blend provided the exact results they were looking for :

“ They offer notable improvements to how well I’m able to focus, stay on task, and grind when it’s time to grind. In practice, this usually looks like a clearer mind and an improved ability to just… chill. With the Clarity and Creativity blends, in particular, I just feel leveled out .”

Backed by clinical trials and real customer experiences, Thesis stands out in the world of nootropics and supplements. The personalized selections prove effective, while the quality ingredients live up to expectations. 

Is Thesis Nootropics Legit?

If you’re wondering if this brand offers products that are too good to be true, this Thesis nootropics review is here to say that it is the real deal .

The brand is backed by numerous clinical trials, which highlight how 86% of customers reported improvements in a wide range of cognitive challenges, while 89% noticed an improvement in their ability to reduce stress and maintain energy.

Is Thesis Nootropics Worth It?

Thesis is an appealing choice in the world of nootropics because it provides a completely customized selection based on your needs and goals. Plus, the ingredients are potent and ensure the best effects—and you only end up paying for the benefits you actually need.

With that in mind, this Thesis nootropics review deems the brand worth the try.

Alternatives

Here are some alternatives to Thesis Nootropics that you might find interesting:

• Mind Lab Pro – This nootropic supplement is designed to improve cognitive function and mental performance. It contains 11 ingredients that work together to enhance memory, focus, and overall brain health.
• Thorne Supplements : If you’re looking for high-quality, science-based supplements, Thorne is a great choice. Their products are designed with the latest research in mind and are rigorously tested for quality and purity. Some of their popular offerings include multivitamins, protein powders, and omega-3 supplements.
• WeAreFeel Supplements : WeAreFeel is a supplement brand that offers a variety of products designed to support different aspects of your health. Their supplements are vegan-friendly and free from artificial colors, flavors, and preservatives. Some of their popular offerings include multivitamins, probiotics, and omega-3 supplements.
• Neuro Gum : If you’re looking for a quick and easy way to boost your focus and energy levels, Neuro Gum is a great option. This gum is infused with caffeine and other natural ingredients that can help improve mental clarity and alertness. Plus, it’s sugar-free and comes in a variety of delicious flavors.
• Neuriva Plus : Neuriva Plus is a brain supplement that’s designed to improve memory, focus, and cognitive performance. It contains a blend of natural ingredients, including coffee fruit extract and phosphatidylserine, that have been shown to support brain health. If you’re looking for a natural way to boost your cognitive function, Neuriva Plus is worth considering.

Thesis Nootropics Promotions & Discounts 

There aren’t currently any Thesis promos or discounts available. That being said, if you subscribe for recurring shipments of your recommended products, you’ll save $40 monthly .

Where to Buy Thesis Nootropics

At the time of this Thesis nootropics review, the products are exclusively available on the brand’s website, takethesis.com .

Is Thesis Nootropics vegan?  

Thesis nootropics are made with only vegan ingredients . That being said, while the brand has taken precautions to protect against cross contamination, the products are not certified vegan.

Is Thesis Nootropics gluten-free? 

On top of being vegan, Thesis products are made without gluten, eggs, or nuts . Again, while the brand strives to protect users against cross contamination, the products are not certified gluten free. 

What is Thesis Nootropics’ Shipping Policy?

If you’re anxiously awaiting your order from this Thesis nootropics review, you’ll be happy to hear that the company offers speedy shipping, sending orders out within 1 business day. After that, packages should arrive within only 1-3 business days . Costs are calculated at checkout.

At this time, Thesis is not able to offer international shipping. This Thesis nootropics review recommends following the brand on social media and signing up for the newsletter to stay up to date with shipping policies. 

What is Thesis Nootropics’ Return Policy?

If you find that your Thesis formula isn’t working out, the company requests that you contact them to make changes and adjustments to ensure you are able to receive the proper help.

If you would still like to make a return, follow these simple steps for a refund:

• Submit your refund request
• Ship the items back within 30 days of the original delivery
• Send an email with your tracking number to the brand
• Return any remaining product in their original packaging to: 

Thesis Returns 902 Broadway

6th Floor New York, NY 

Once your return has been received, a refund will be processed and email confirmation will be sent. It’s also important to note that the brand can only refund one month’s supply per customer and return shipping is the customer’s responsibility. 

How to Contact Thesis Nootropics

We hope you enjoyed this Thesis nootropics review! If you have any further questions about the brand or its products, you can contact them using the following methods:

• Call 1 (646) 647-3599
• Email [email protected]

902 Broadway Floor 6 New York, NY 10010

If you’re looking for other ways to boost your productivity via supplements, check out these other brands we’ve reviewed:

Thorne Supplements Review

WeAreFeel Supplements Review

Neuro Gum Review

Neuriva Plus Review

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Thesis Nootropics Helped Me Ditch My 3-Coffee-A-Day Habit

Here's what to know about the personalized supplement brand.

As someone who pours herself a tall glass of iced coffee three times a day — and sometimes even more, oops — I figured it wouldn’t hurt to look into other ways to boost my energy and focus. Of course, I also try to get enough sleep, water, and exercise, too. But I was also down to try a few supplements from Thesis, a nootropics company that aims to make you feel more productive with its plant-based blends.

If you’re not familiar, nootropics are similar to adaptogens in that they’re a class of functional plants that are buzzy in the wellness world. But nootropics — which include ingredients like ashwagandha , L-theanine , choline , and functional mushrooms — are more focused on activating different parts of your brain to support motivation, mood, memory, and cognitive processing . That’s why they’re sometimes called smart drugs or cognitive enhancers — and thus have a different role to play than everyday vitamins.

At Thesis, you’re hooked up with a kit of personalized vitamins , adaptogens , and nootropics that are meant to help support you in accomplishing your goals and feeling more energized and productive. I tried them out for a month and I have some thoughts. Here’s what it was like to try Thesis, in case you’re also a coffee fiend who could use a little more focus and energy.

• Price: $79/monthly subscription
• Best for: Energy, focus
• My rating: 4/5
• What we like: Personalized supplements, supportive coaches
• What we don't like: Can seem pricey, you have to be ready for some trial and error

What Is Thesis?

To get started, you’ll first take a quiz on the Thesis website that asks you about how you feel on a day-to-day basis, how much coffee you drink, what your energy levels are like, and how much you sleep (among other lifestyle questions) so that it can determine the best supplements for you. It’ll then send you a starter kit with six different supplement blends targeted for each issue you might be experiencing. From there, it’s up to you to decide which ones you want to continue using. It works like a process of elimination — you experiment by taking each supplement for six days to see whether or not it feels effective.

The Thesis line features eight different supplement blends: Creativity, Focus, Motivation, Clarity, Energy, Motivation, Confidence, and Logic. Though the brand notes it would love to formulate one pill that works for everyone, brain chemistry is so complex, so it decided it’s better to take the long route and have customers try multiple supplements in order to find the best fit for their noggin. That’s why Thesis also puts you in contact with a wellness coach, so you can chat and ask questions with an expert along the way.

How Do Nootropics Work?

Nootropics are meant to allow your brain to do its thing, only faster and with more efficiency. So, instead of slogging away at your desk with brain fog , you might notice that you feel perkier, extra organized, and more on-point than you normally do as you continue taking the supplements.

Some of the blends contain the nootropic acetylcholine , which is a neurotransmitter from the essential nutrient choline known for memory, learning, and healthy brain function . There are also plenty of amino acids, vitamins, and plant-based adaptogens in each packet to fight off fatigue and stress while protecting your brain from toxins so it’s easier to take in info — and actually remember what you learned. Other staple nootropics include ginkgo biloba , certain kinds of mushrooms, and caffeine, each of which plays a unique function in your cognitive function.

My Experience

When I took the Thesis quiz , I said that I wanted to improve my energy, focus, and mood. A few days later, I received my starter kit, which contained Clarity , Confidence , Motivation , and Logic all laid out in cute little boxes. You’re supposed to pick one — each box contains six sachets full of pills — and take a packet a day for six days. I was immediately drawn to Clarity, a supplement combo that’s supposed to help with high-pressure situations, concentration, and tasks that require focus and attention. It has Lion’s Mane extract (a mushroom), caffeine, L-theanine , and a few other ingredients meant to support a calm, focused flow. The idea is to take the supplements in the morning so they kick in before you start your day, and most of the effects are said to last from four to six hours.

I’d been taking Clarity for a few days when I had a phone call with Cindy Yan , a Thesis wellness coach and nootropics expert. We chatted about my usual routine, how I’d been feeling, and any questions I had about the process. When I said I felt a slight uptick in focus, but nothing too dramatic, Yan told me the first couple days are called the “loading phase” which is when the nutrients work their way into your body. If you don’t feel anything after that point, it’s a sign the supplement isn’t necessary or right for your neurochemistry. If you do like how you feel, it’s a keeper.

As we chatted about my routine, Yan realized I’d benefit from Creativity, an ashwagandha-based supplement meant for brainstorming and public speaking, so that I could feel like a rockstar at work. I also told her that I tend to crave a nap around 3 p.m., so she suggested the Energy supplement made with choline and mango leaf extract , which you can take every day or on extra-busy days, before a workout , or whenever you want to feel alert.

Talking to a coach as I tested the supplements was a true perk. While the quiz got me started with some great options, having access to Yan helped me hone in on what I truly needed.

Yan suggested I log how I felt every day as I took each supplement so I could keep track of any noticeable differences. A week in, I looked at the scribbles in my notebook and noticed that I did seem more productive during the six days I took Clarity. I wasn’t launching rockets to the moon, but I was getting through my emails and typing away like a woman on fire.

The next supplement on my agenda was Energy, a blend meant for busy days, intense workouts, and staying alert thanks to its mango leaf, theacrine , caffeine, and n-acetyl cysteine — and this is the one that gave me the most benefit. Yan was right on the money. She said I could take it in the morning and/or right after lunch to nip my afternoon slump in the bud, and it truly worked — no fourth mid-day coffee for me.

The more I took Energy, the less I felt like I needed to unhinge my jaw and dump as much cold brew into my face as possible. I found myself drinking a sensible cup or two in the morning, and that was that. Thesis says you can feel the effects of the supplements in as little as 30 minutes or it can take up to five days for all the benefits to sink in as your body and brain adjust. For me, though, Energy kicked in pretty quickly.

The Bottom Line

Typically, Thesis users land on two or three supplements for their regimen. After the month-long trial phase, you can order just the ones you want and forget about the rest. Personally, I’m sold on Energy and can see myself hanging onto Clarity, too.

Thesis seems to have figured things out in the nootropic supplement realm. While the boxes seem pricey, it isn’t so bad when you think about buying each supplement on your own individually — and the fact that you get a wellness coach, too.

TL;DR: I’d recommend it for anyone who feels fatigued, unproductive, or unfocused, or for folks who rely on caffeine to get through the day, like me. You might just find that there’s a better way.

Studies referenced:

Baba, Y. (2021). Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study. J Med Food. doi: 10.1089/jmf.2020.4803. Epub 2021 Mar 22.

Coqueiro, AY. (2019). Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition. Nutrients. doi: 10.3390/nu11040863.

Gelabert-Rebato, M. (2019). A Single Dose of The Mango Leaf Extract Zynamite ® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women. Nutrients. 2019 Oct 28;11(11):2592. doi: 10.3390/nu11112592.

Lai, PL. (2013). Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. doi: 10.1615/intjmedmushr.v15.i6.30.

Malík, M, Tlustoš P. Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs. Nutrients. 2022 Aug 17;14(16):3367. doi: 10.3390/nu14163367. PMID: 36014874; PMCID: PMC9415189.

Mokhtari, V. (2017). A Review on Various Uses of N-Acetyl Cysteine. Cell J. doi: 10.22074/cellj.2016.4872.

Penry, JT. (2008). Choline: an important micronutrient for maximal endurance-exercise performance? Int J Sport Nutr Exerc Metab. doi: 10.1123/ijsnem.18.2.191.

Sam, C. (2022). Physiology, Acetylcholine. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32491757.

Silberstein, R. B. (2010). Examining Brain-Cognition Effects of Ginkgo Biloba Extract: Brain Activation in the Left Temporal and Left Prefrontal Cortex in an Object Working Memory Task. Evidence-based Complementary and Alternative Medicine : ECAM , 2011 . https://doi.org/10.1155/2011/164139

Suliman, NA. (2016). Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic. Evid Based Complement Alternat Med. doi: 10.1155/2016/4391375.

Todorova, V. (2021). Plant Adaptogens-History and Future Perspectives. Nutrients. doi: 10.3390/nu13082861.

Wiedeman, AM. (2018). Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. Nutrients. doi: 10.3390/nu10101513.

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Thesis Nootropics Review: Extended Test Period Results

July 9, 2024

In this Thesis Nootropics review, we're looking at a range of supplements that claim to boost brain function with six different blends targeting areas like energy, focus, or creativity. Thesis says their formulas are customized for you, but we wanted to see if they really work. Over 12 months, we tested these supplements to see what's in them and if the science supports their big claims. Thesis features ingredients like Zynamite® and TeaCrine® that have been getting a lot of attention. But do they actually do anything? With so many blends, it can be confusing—do you really need different ones for energy and focus? We also wondered if these blends are missing important ingredients that could make them better. To give you a full picture, we compared Thesis with NooCube, a top nootropic that offers a simpler, all-in-one formula claiming to cover more benefits. We're here to break down the facts and help you decide if Thesis is worth it or if you should look at other options for boosting your brainpower.

Overall Verdict

3.1/ 5 Stars

• Limited Customization: Thesis Nootropics' customization is restricted to a small range of standardized products.
• Forced Trade-offs: Customers must choose between different cognitive benefits based on a questionnaire.
• Narrow Focus: The approach prioritizes specific nootropic effects rather than offering a comprehensive solution.
• Our Preference: A more inclusive formula like  NooCube provides broader cognitive and brain health benefits without trade-offs.

Introduction To Thesis Nootropics

Thesis Nootropics differentiates itself from other nootropic suppliers by emphasizing personalized supplements rather than generic solutions. Their online platform offers customized formulations tailored to individual needs and preferences.

Although the name 'Thesis Nootropics' may not be familiar, the company has been around for some time, originally known as FindMyFormula.com before rebranding. They claim their extensive experience in the world of supplements and their nootropic research enables them to continually refine their formulas using rigorous scientific and data-driven approaches.

The Personalized Nootropic

The customization process at Thesis Nootropics is time-consuming but reasonably straightforward. Customers start by visiting the website and filling out a questionnaire that collects basic information—no need for lab tests or medical history. While some might argue for a more detailed approach, this non-invasive method apparently helps tailor recommendations to individual preferences.

Once the questionnaire is completed, customers receive their order within 1-3 business days. Thesis suggests treating the first shipment as a trial, encouraging users to experiment with different blends before deciding on a specific formula. This feedback helps refine their algorithm and improves future recommendations.

While it might seem like a strategy to promote more purchases, it's important to note that Thesis allows customers to test up to four different blends before committing to a long-term option. This system lets users fine-tune their choices without the frustration of extensive trial and error.

Personalized Support At A Premium Price

• Each customer is assigned a personal nootropics expert. This expert serves as a coach and pharmacist, offering virtual consultations to help refine a user's nootropic regimen, track progress, and answer any questions. The brand claims this elevates Thesis beyond just providing supplements, instead making it a comprehensive well-being program.
• This tailored approach is premium priced. A starter kit is over a hundred dollars, and a monthly prescription costs around eighty dollars. This is more expensive than the highest-quality alternatives like NooCube . Ultimately, consumers must decide whether the additional support and tailoring justify the higher price point.

The Nootropic Endorsed by Dr. Andrew Huberman, Rich Roll And Dr. Gabrielle Lyon

• Dr. Andrew Huberman's claim: "I've been using Thesis for over a year now, and I can confidently say that their nootropics have been a total game changer for me."
• Rich Roll's claim: "Thesis has provided a substantial benefit to my ability to focus. Creativity works best for me - I take it 30 mins before a podcast or writing and it helps me get in the zone."
• Dr. Gabrielle Lyon's claim: "I work with CEOs, celebrities, and other top performers in my practice. Thesis is what I recommend and take personally for focus and cognition. I even used it to help me nail my first TedX talk."

Thesis Nootropics Claimed Benefits

Thesis nootropics overview.

Thesis Nootropics provides a comprehensive cognitive enhancement solution that not only shares the common benefits of other high-quality nootropic supplements but also is a uniquely tailored solution that set them apart from their competitors. It's important to note that Thesis Nootropics does come at a higher price point compared to alternatives like Hunter Focus. However, the personalized approach and access to expert guidance may justify the additional cost for users who want to invest in a more advanced and tailored cognitive enhancement solution.

What Does Thesis Offer?

Thesis Nootropics presents a range of blends aimed at various aspects of mental function, such as boosting energy, enhancing clarity, improving memory, reducing brain fog, elevating mood, lowering stress, and increasing focus. These are typical claims for high-quality nootropic supplements, aiming to provide users with the cognitive support they seek.

Thesis Nootropics differentiates itself with two primary features. Firstly, it offers personalization by tailoring supplements to individual needs through an online questionnaire. While other nootropics like NooCube might suit most people, the personalized approach of Thesis aims to target specific cognitive goals for optimal results. However, some may argue that this method is not detailed enough for truly customized supplements, as it doesn't include comprehensive personal health information.

Once the questionnaire is completed, customers receive their product within a few days. Thesis encourages treating the initial shipment as a trial to test various blends before committing to one. This feedback supposedly helps improve their algorithm and future recommendations. Critics might view this as a way to promote more purchases, but Thesis does allow users to try up to four different blends before making a long-term decision, which helps minimize trial and error.

Another aspect Thesis promotes is access to a team of experts. While this might seem excessive for those satisfied with basic nootropic knowledge, it could be valuable for users wanting deeper insights into cognitive enhancement. The added cost for this personalized support might be seen as justified given the expert guidance and customized advice offered by the Thesis team. These experts provide virtual consultations to help refine the user's regimen, track progress, and answer any questions, aiming to elevate Thesis Nootropics from a mere supplement to a comprehensive wellness program. However, for many, this level of support might seem unnecessary and an additional expense.

Thesis Nootropics provides a comprehensive cognitive enhancement solution that not only shares the common benefits of other high-quality nootropic supplements but also is a uniquely tailored solution that set them apart from their competitors. It's important to note that Thesis Nootropics does come at a higher price point compared to alternatives like NooCube . However, the personalized approach and access to expert guidance may justify the additional cost for users who want to invest in a more advanced and tailored cognitive enhancement solution.

Research And Evidence

Thesis haven't conducted independent research into the effectiveness of their nootropic blends. However, they do cite a total of 18 scientific papers in support of 6 of the ingredients used across the range. Whilst this number of citations seems impressive at first, in reality it's 3 citations for each of only 6 ingredients:

• Teacrine [1,2,3]
• Dynamine [4,5,6]
• Zembrin [7,8,9]
• Synapsa [10,11,12]
• Ashwagandha [13,14,15]
• Alpha GPC [16,17,18]

Given that over 30 ingredients are used across Thesis' range, there is a lot of scientific evidence missing. Overall, Thesis nootropics are dosed at effective levels, but some ingredients are not well evidenced - and what evidence is searchable is not easy to locate. 

Ingredients And Options

Nootropic formulations from Thesis encompass various blends, tailored to the individual, concentrating on enhancing distinct aspects of cognitive function and brain health. These blends exhibit unique ingredient compositions, although some similarities are present among them. The Energy blend, is designed to augment energy levels, combat fatigue, and bolster mental endurance. It incorporates choline, recognized for its benefits in memory and learning, as well as NAC and NALT, which contribute to detoxification and neuronal communication, respectively. Additionally, proprietary ingredients such as Sabroxy® (for dopamine increase and memory enhancement), TeaCrine® (for energy, motivation, and cognitive function), and Zynamite® (for physical and mental energy) are included. Conventional nootropic components, like caffeine (for energy) and L-theanine (for stress response improvement), are also present. Clarity, has a somewhat unconventional ingredient list, yet still comprises many expected nootropic components. 7,8-DHF and Alpha GPC both facilitate neural communication, neurogenesis, and neuroprotection. Epicatechin and Lion's Mane contribute to neuroprotection while enhancing mood, memory, cerebral blood flow, and memory consolidation. Caffeine and L-theanine are also included, addressing stress response and energy. The Motivation blend aims to boost willpower and productivity while curbing procrastination, despite motivation being a difficult aspect to define or quantify. Ingredients such as Artichoke extract (for circulation and stress response), Dynamine® (for mood elevation and sustained energy without caffeine-related crashes), Forskolin and L-phenylalanine (together improving cognitive function, mood, and focus), and vitamin B12 (for energy and nerve health) contribute to this goal. Caffeine and theanine are also part of this blend. The Creativity formula, designed to enhance verbal fluency and confidence, contains Agmatine, Ashwagandha, and L-theanine (for stress and anxiety management), Alpha GPC (for memory, neuroprotection, and neurogenesis), and Zembrin® (for mood regulation and increased cerebral blood flow). Caffeine is also present in this blend. Lastly, the Confidence blend aims to promote self-assurance by targeting stress and insecurity responses. Ingredients include magnesium, ashwagandha, saffron, sage, and DHH-B, which collectively help improve confidence.

Overall: 4.0 / 5

• Personalization: Thesis nootropics offer customized blends that cater to individual needs, enhancing the effectiveness of cognitive support.
• Expert Consultations: Access to expert advice is available, providing valuable guidance and insight for users seeking to optimize their cognitive health.
• High-Quality Ingredients: Thesis nootropics are formulated with premium ingredients, ensuring safety and effectiveness for consumers.
• Comprehensive Support: The customer care provided by Thesis not only includes expert consultations, but also extends to answering questions and addressing concerns, contributing to a positive overall experience.
• Cost: Thesis nootropics may be more expensive than alternatives, potentially deterring budget-conscious consumers.
• Limited Personalization: Although Thesis offers personalized blends, the customization may not be as precise or in-depth as some consumers would prefer.
• Subscription Model: Some individuals might find the subscription-based model inconvenient or inflexible, preferring one-time purchases instead.
• Overemphasis on Customer Care: The extensive customer support, while commendable, may be perceived as excessive by some consumers who prefer a more straightforward, self-directed approach to their supplement regimen.
• Over complicated approach to nootropics for majority of people. A more comprehensive alternative such as NooCube, is likely to better suit most people's needs.

Potential Side Effects of Thesis Nootropics

• The Energy blend contains Zynamite®, a natural ingredient derived from the mango tree [19]. It may cause mild side effects, such as headaches, nausea, and stomach discomfort. TeaCrine® and Sabroxy® are also included in this blend, which may cause nervousness, insomnia, and jitteriness. Caffeine and L-Theanine, which are optional ingredients, may also cause similar side effects.
• The Clarity blend contains 7,8 Dihydroxyflavone, a natural ingredient that may cause mild side effects, such as nausea, diarrhea, and headaches [20]. Camellia Sinesis Extract, which is also included, may cause insomnia, nervousness, and stomach discomfort. Lion’s Mane 8:1 Extract may cause itching, skin rashes, and gastrointestinal discomfort [21].
• The Creativity blend contains KSM-66 Ashwagandha, which may cause mild side effects, such as stomach discomfort and diarrhea [22]. GS15-4 Panax Ginseng may cause nervousness, insomnia, and headaches. Zembrin® may cause dizziness, nausea, and dry mouth [23].
• The Logic blend contains Triacetyluridine, which may cause mild side effects, such as headaches, nausea, and stomach discomfort [24]. Vegan Omega-3 Lysine complex (EPA + DHA) may cause gastrointestinal discomfort and nausea. Theobromine may cause insomnia, restlessness, and stomach discomfort [25].
• The Motivation blend contains Forskolin, which may cause stomach discomfort, diarrhea, and headaches [26]. Methylcobalamin may cause mild side effects, such as nausea and diarrhea. Dynamine may cause nervousness, insomnia, and headaches [27].
• The Confidence blend contains Saffron extract (affron®), which may cause mild side effects, such as dry mouth, dizziness, and nausea [28]. Ashwagandha extract (Shoden®) may cause stomach discomfort, diarrhea, and headaches [29]. Sage extract may cause gastrointestinal discomfort, nausea, and headaches.

Best Alternative to Thesis Nootropics

If your focus is sharply honed on enhancing a particular aspect of cognitive function and you don't mind shelling out more for targeted support, Thesis might suit your needs. Its range of blends is designed to pinpoint specific nootropic benefits, whether that's boosting your energy, improving clarity, sparking creativity, enhancing logic, motivating success, or building confidence. But, it comes at a premium, both in terms of cost and the necessity to navigate through its segmented approach to find what works best for you. However, for those seeking a broader spectrum of cognitive benefits—encompassing not just temporary performance boosts but also long-term brain health, mood stabilization, and memory enhancement—there are more comprehensive and cost-effective alternatives available. Among these,  NooCube stands out in our testing as the most effective nootropic available. NooCube's formula supports overall brain function without the need to mix and match different products. It delivers a synergistic blend of ingredients known for their efficacy in enhancing cognitive function, supporting neuron health, and providing the body with the foundational nutrients necessary for optimal mental performance. With NooCube, we experienced a more holistic approach to cognitive enhancement, making it our top recommendation for those looking to invest in their brain health and cognitive capabilities.

While Thesis aims to focus on specific areas of brain health with different products, NooCube makes things simpler. It's one supplement that aims to boost memory, help you focus better, and make your mind clearer. NooCube packs ingredients like Panax Ginseng, L-Theanine, and Bacopa Monnieri, each and every ingredient is proven to support cognition and brain health in clinical studies - and each has been dosed at clinically proven levels. Thesis' approach is interesting but the cost, complexity and narrow range of benefits let it down. If you're looking for something that covers more bases and keeps everything straightforward, NooCube is the way to go. With its latest update in February 2024, NooCube has gotten even better, making it a top choice for anyone looking to give their brain a comprehensive boost.

Thesis Nootropics claims to stand out with its personalized approach, but it's worth questioning if this is really necessary. A more comprehensive solution like NooCube   might be a better choice, offering the benefits of multiple Thesis blends in one product and without the time-consuming need to complete a questionnaire and make unnecessary trade-offs. NooCube's latest version, released in February 2024, has recently improved on an already great product.

When considering the cost, Thesis Nootropics is expensive. Whilst their customer support is praised, its necessity for the average user is debatable. For those who find value in this added support, the higher price might be justified. However, many users may find the cost excessive.

To give you an idea, a one-month supply of Thesis nootropics without a subscription costs about the same as three months of NooCube. NooCube provides a high-quality nootropic at a more affordable price and saves you the hassle of completing a questionnaire.

Do nootropics work?

Many nootropic ingredients and formulations have been shown to improve attention, memory, and learning, while others may promote relaxation and reduce stress and anxiety. For example, caffeine is a commonly used nootropic that can increase alertness and reduce fatigue, while L-Theanine, an amino acid found in tea leaves, has been shown to promote relaxation and reduce stress.

Are nootropics safe?

Nootropics that contain natural ingredients and have undergone clinical testing are generally considered safe when used properly. It is important to follow recommended dosages and to avoid taking more than the recommended amount. It's also worth being aware of any potential side effects and if necessary consult with your doctor if you have any underlying medical conditions.

What should I expect from a nootropic?

When taking a nootropic supplement, you should expect to experience some improvement in cognitive function, such as enhanced memory, concentration, and mental clarity. The effects of a nootropic will vary depending on the specific ingredients and dosage of the supplement, as well as individual factors such as age, overall health, and your lifestyle.

Which nootropic should I buy?

Popular nootropic supplements include NooCube, Mind Lab Pro, and Vyvamind. NooCube contains a blend of ingredients that may improve memory, focus, and overall cognitive function. Mind Lab Pro is designed to support brain health and cognitive performance through a variety of ingredients, including vitamins, minerals, and plant-based compounds. Vyvamind is a premium nootropic supplement that focuses almost exlcusively on cognitive function and mental performance. Read DBEM's guide to nootropics to see how the leading nootropic brands compare.

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• Zynamite®: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502219/
• 7,8 Dihydroxyflavone: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046999/
• Lion’s Mane 8:1 Extract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237458/
• KSM-66 Ashwagandha: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687242/
• Zembrin®: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120705/
• Triacetyluridine: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025289/
• Theobromine: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335269/
• Forskolin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663611/
• Dynamine: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491065/
• Saffron extract (affron®): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376420/
• Ashwagandha extract (Shoden®): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438434/

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Thesis Review: Are Personalized Nootropics Legit?

Calloway Cook Calloway Cook is the President of Illuminate Labs and has reviewed over 1,000 clinical trials. See full bio . , Author | Taylor Graber MD Taylor Graber is a Medical Doctor (MD) and a practicing anaesthesiologist. He's also an entrepreneur who runs a health and wellness startup. See full bio . , Medical Reviewer Last updated: Nov 05, 2023

Calloway Cook Calloway Cook is the President of Illuminate Labs and has reviewed over 1,000 clinical trials. See full bio . , Author

Taylor Graber MD Taylor Graber is a Medical Doctor (MD) and a practicing anaesthesiologist. He's also an entrepreneur who runs a health and wellness startup. See full bio . , Medical Reviewer Last updated: Nov 05, 2023

We review published medical research in respected scientific journals to arrive at our conclusions about a product or health topic. This ensures the highest standard of scientific accuracy.

Illuminate Labs has a team of medical experts including doctors and Registered Dietitians who are assigned to review the accuracy of health claims and medical research summaries based on the relevancy of their expertise to the article topic.

The focus of our articles is to share our opinion on the potential efficacy and safety of health trends and products.

T hesis is a wellness brand that sells personalized nootropics. The brand sells supplements with unique names like “Creativity” and “Motivation,” and claims that their individualized products are “based on your unique brain chemistry.”

But is there legitimate research backing personalized nootropics or is this just a marketing spin? Why does the brand ask for so much personal data? Are their supplements well-formulated? And how do real users rate and describe the effects of Thesis?

In this article we’ll answer all of these questions and more as we share our concerns about the marketing practices and health claims of Thesis.

We’ll also analyze the ingredients in one of their formulations based on medical research to give our take on whether or not it's likely to be effective. We’ll share customer reviews of Thesis nootropics including some from individuals with ADHD.

Is the “Personalized” Approach Fake?

The branding around Thesis is of “personalized nootropic formulas,” however this may be entirely untrue.

We submitted test answers into the health intake form of their site, along with a fake email, and after submitting all of this information we were brought to their “Starter Kit” landing page which is accessible at this link .

If you access the above link in a new window, the products suggested are the exact same, which suggests that Thesis is really collecting sensitive customer health data based on the guise of “personalized” supplements, while providing no additional value, which is a highly questionable marketing approach in our opinion.

The concept of “personalized nootropics” doesn’t even make sense, because the manufacturer would have to literally formulate and package them when a customer placed an order, unique to each customer’s order which is highly unlikely. It would make no business sense for a company to formulate millions of unique products and would be logistically impossible.

It appears that Thesis simply recommends some of their supplements to consumers based on their needs, which is not a “personalized nootropic formula,” it’s a personalized recommendation which literally any brand could offer.

This leads us to our second concern about this brand.

Rather than simply selling supplements, they require users to complete a questionnaire which asks a number of sensitive health questions. 

As shown above, the brand requires users to answer questions about their gender identity and their alcoholic intake in their health quiz. What does this have anything to do with nootropics, and why would any user share this data with a random supplement startup?

We would recommend avoiding this brand based on these marketing and data collection practices alone, but in the next section we’ll analyze the formulation of one of their products.

Ingredient Analysis

Thesis’ “Motivation Formula” contains five active ingredients: l-phenylalanine, Dynamine, vitamin B12, forskolin and artichoke extract.

L-phenylalanine is an amino acid that Thesis describes as supporting mood, attention and motivation, however these claims are uncited and we can’t find any medical evidence supporting them. 

Most of the clinical research we found on this ingredient involves obesity, with this clinical trial finding that l-phenylalanine may increase the sense of fullness and decrease calories consumed in overweight individuals, but only at a dose 20x that in Thesis’ supplement.

Dynamine is a trademarked form of methylliberine, which is a chemical compound that can be isolated from coffee beans and tea. Thesis claims that this compound “supports alertness” but this claim is uncited and we can’t find any medical evidence supporting it.

The manufacturer of this ingredient is a company called Compound Solutions, and the company even states on their website that this ingredient is “typically used in combination with caffeine and TeaCrine,” because all three of the clinical trials that the manufacturer cites on their website use Dynamine in combination with either caffeine or TeaCrine.

However, there is no caffeine or TeaCrine in Thesis Motivation.

Vitamin B12 is often included in nootropic formulations, but we’re unsure why. As we referenced in our review of another nootropic supplement called Noocube which also contains this ingredient, we can’t identify any medical evidence that vitamin B12 improves cognitive function in healthy adults without a vitamin B12 deficiency.

Forskolin was shown in an animal study to reduce memory loss, but the lowest dose used was equivalent to over 200% of the human-equivalent dose in Thesis. We can’t identify any clinical trials with human trial participants proving this compound to be an effective nootropic.

Artichoke extract is the final active ingredient, and Thesis claims that this ingredient “supports blood flow and promotes stress management.” These claims are uncited and we’re unclear on why this ingredient would be included in a nootropic formula, as even the stated health claims do not reference an explicit improvement in cognitive function.

Thesis fails to publish inactive ingredients for Motivation, which is an important consumer safety concern.

Overall we do not consider Thesis Motivation likely to be effective for improving cognitive function or productivity as we are unable to identify a single active ingredient that we would consider effective at the given dose, based on a review of clinical studies.

We do not recommend this supplement or brand, and consider this product to be one of the worst nootropic formulations that we’ve reviewed on Illuminate Health. Most nootropic supplements we review at least contain one effectively-dosed active ingredient.

We Tried Thesis Ourselves

One of our product testers named Matt Donnelly tested Thesis. Here's his experience:

I spent the month trying out the starter pack, which included CLARITY, MOTIVATION, LOGIC, and MOTIVATION.

Of the four, the only one that seemed to have any positive effect was LOGIC. It's good for “Research projects” and “Complex problem-solving” according to the packaging.

I was hoping for good results because I had been sidetracked from creative projects. It seemed like this one may have contributed to more focus overall and focused attention.

On some days I got very tired a few hours after taking the capsules, and needed to lie down in the afternoon.

There are three or four pills in each packet. It seemed to me like a lot to consume on a daily basis, and the pills are large so they could be challenging to swallow.

Overall, I would rate Thesis 3/10 and I wouldn't purchase this product again.

Thesis User Test

A YouTube creator named “LUKAS YAN” reviewed Thesis nootropics and shared his thoughts on whether or not the supplements improved his physical and mental energy:

Will Thesis Nootropics Cause Side Effects?

Thesis Nootropics do not appear to have been studied in any clinical trials, so it’s impossible to say for certain whether or not they’re likely to cause side effects. However, we can make an educated guess based on their formulations.

Most of the active ingredients in Thesis supplements appear to be safe and well-studied. We don’t have access to the full set of the brand’s supplements because instead of transparently posting all product pages they rely on the “individualized” marketing.

Our concern in regard to side effects is that the brand fails to clearly publish inactive ingredient information, and some inactive ingredients can cause side effects.

We hope that in the future Thesis publishes inactive ingredients in the same section where active ingredients are published for each supplement they sell. This is important for consumer safety.

Our Clean Nootropic Picks

Mind Lab Pro   by Performance Lab is our top premium nootropic pick.

This is the first Illuminate Labs Certified supplement, and   has been shown to be effective for short-term cognitive improvements in   two   clinical   trials   published in peer-reviewed journals.

Performance Lab MCT Oil   is our top food-based nootropic pick.

MCT oil  is derived from coconut oil, and  improved memory recall by 20% in adults  in a 2022  meta-study .

Illuminate Labs Ginkgo Biloba Extract   is our top herbal nootropic pick.

A  medical review  published in the  Psychopharmacology  journal  found that ginkgo biloba supplementation improved attention and cognitive performance in healthy, young adults.

Is Thesis Effective for ADHD?

We don’t recommend using Thesis supplements to treat any specific health condition.

There are several TikTok reviews from individuals with ADHD who tried Thesis supplements.

A TikTok user named Syd shared her experience using Thesis while having ADHD:

@sydneydelucchi Lets try @takethesis ! #nootropics #nootropicsforadhd #adhd ♬ original sound - Syd 🦋

A TikTok creator named Mike Cribbs shared her experience:

@mikacribbs Replying to @adrienne here are my initial thoughts using @Thesis 💙🩵 #takethesis #nootropics #thesis ♬ Fukashigi no Carte Lofi Hiphop (Bunny Girl Senpai) - bvyunx

We disagree with the way Thesis markets their products, and we recommend that consumers avoid giving sensitive health data to dietary supplement startups unnecessarily.

The one Thesis supplement that we analyzed based on its active ingredients, called Motivation, was underwhelming. We were unable to identify any effectively-dosed ingredients based on a review of medical research, and the brand fails to clearly publish inactive ingredient information or cite the health claims made about their ingredients.

We do not recommend Thesis supplements although we don’t consider it likely that the supplements will cause side effects.

Some TikTok users with ADHD who tried Thesis supplements had relatively negative feedback.

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Thesis Nootropics Review

Nootropics fan and expert James Dixon examines this personalized supplement in our Thesis Nootropics review. Find out how he rates it after testing it below…

Last Updated:

August 6, 2024

Written by James Dixon – fact checked by Jason M & the editorial team

James Dixon is one of the key players in the SOMA Analytics’ team. He is a personal trainer and is educated to Masters level in Philosophy. He is a published author and is a keen advocate of high quality nootropic supplements.

This article complies with the SOMA Analytics editorial policy. Full details of which can be found here

SOMA Analytics is supported by our readers. We may earn a commission when you purchase through links on this page. Our content is checked for factual accuracy by our editorial team and is written by expert nutritionalists.

Nootropic supplements – so called ‘smart drugs’ – are all the rage. They represent a rapidly expanding corner of the supplement market and have had genuinely life-altering effects on many, many users – myself included.

They’re not actually ‘drugs’ as you would think of them. This isn’t medication we’re talking about, here. Rather, these supplements are compounds of natural ingredients designed to work together to boost your cognitive health and brain function .

A good nootropic should help you feel smarter… which is a bold claim. There is something to it, however.

Nootropics should aid your focus, learning skills, memory, and creativity . They should reduce brain fog, anxiety, and lethargy , replacing them with clarity, calm, and plenty of low-key energy.

If you struggle with any of these symptoms, there is a good chance that you could do with a quality nootropic, which is exactly what we’re looking at today. Though perhaps not the best of the best, Thesis Nootropics offer a range of products that are all intelligently crafted and, to a degree, fairly personalized.

And when I say they aren’t the best of the best, this doesn’t mean much. The nootropic market is crowded. There are a couple of standout items out there – NooCube springs to mind. Playing second fiddle to these is still a large accomplishment.

Let’s dive in and take a full look as I dig in to this Thesis Nootropics review.

Quick Verdict: Thesis Nootropics

Thesis Nootropics have a great range of different nootropics aimed at different needs. They also have an excellent nutritional coaching system to support you.

However, the reality is that most people won’t really gain from this additional 5%. Products such as NooCube offer greater value for money with similar nootropic benefits.

Introducing Thesis Nootropics

As above, Thesis Nootropics are smart drugs. They offer high-quality nootropics that are designed to help with various aspects of your cognitive health and function. Their products all contain top-shelf ingredients all proven to help your brain to work optimally.

They also do something a bit different. Where most nootropics – and most other supplements, for that matter – offer you the same over-the-counter pills as they would offer anyone else, Thesis bring personalized supplements to bear.

Through their online store, you can fully personalize your nootropic options to make the most of your own specific needs and circumstances .

It’s really quite clever.

They started out as FindMyFormula.com before rebranding a few years back. So, although ‘Thesis Nootropics’ may seem like a newcomer to the market, they have actually been around for a long time.

They bring this pedigree to the fore with this product. With a customer base of over half a million users, they have proven themselves and then some.

The data they hold from their research into nootropics is peerless – I can’t think of anyone with better. And they use it well, crafting and re-crafting their formulae with proper, diligent science and data in mind.

The personalization process is actually quite straightforward too – at least, it is for the customer, which is always nice.

You start off by going to their website and taking their questionnaire. Don’t worry, it’s not all that comprehensive, asking for only basic information. There is no need to take any lab tests or divulge your medical history.

However, it’s enough for them to make a match for the nootropic blends that will best suit your needs.

Optimize Your Mental Agility

Claim access to the full potential of your brain

with these optimum nootropic stacks and

exclusive discounts …

There are two ways to read this, of course. Either, it’s a non-invasive way to tailor your supplements, or it’s not a deep enough dive, so how well tailored can they really be?

I felt a little let down, here. When I came in being promised ‘personalized supplements’ I had higher hopes. Instead, it’s just sort of asking what you want and pointing you in the right direction.

It’s nice, it’s just not quite as revolutionary as the literature and branding suggest.

The next phase is good, though. They’ll send your shipment out to arrive within 1-3 business days .

However, they ask you to treat this as a sample; they invite you to try out a few different blends of theirs before picking it.

This data is fed back to their algorithm, further enhancing their future prescriptive capabilities. Again, you can read this cynically or not.

Either it’s a great way to search out what works best for you, or it’s doing their job for them and getting you to buy plenty of their products in the process… if their original diagnostics are that good, why do you then need to cycle through their catalog?

Except that they allow you to try up to four before committing to a longer-term formul a. Pair this with that original questionnaire and, cynicism on hold, you have an excellent and innovative product.

It helps you to refine your own choices without having to do the legwork, which can often take months, a lot of money, and a fair amount of trial and error.

The final part is my favorite part, and dispels much of my lingering cynicism…

As a Thesis customer, you are assigned a nootropics expert , a sort of coach and pharmacist in one. You can consult with them virtually at any time.

They can help you to further refine your nootropics regime, find ways to optimize your results, track your progress and wellbeing, and generally educate you by ably answering any questions you might have.

I love this. It takes Thesis to the next level – it’s less a supplement and more a course focused on wellbeing.

It’s not cheap, I’ll warn you now. A starter kit will go over a hundred dollars. A prescription will run to a monthly bill of around eighty.

This is roughly twice what you would pay for something like NooCube or Mind Lab Pro , supplements I consider to be the best of the best. It’s around four times what you could pay for a lower-end, albeit workable nootropic.

You’re presented with a choice, then: pay extra for the support and tailoring, or pay a far more reasonable amount for something that will still do the job incredibly well.

Why Choose Thesis Nootropics?

The benefits of Thesis Nootropics are fairly straightforward.

Firstly, Thesis shares the same benefits as any other good-quality nootropic supplement. They offer several blends (more on this below), which between them can improve your cognitive function from pretty much every angle.

You can boost your cognitive energy, improve your clarity, improve your memory and learning abilities, clear brain fog, improve your mood, reduce your stress levels, and boost your ability to focus, among other things.

This is all good. It’s what you’re looking for in a nootropic in the first place.

But, of course, the benefits go beyond this. The two main things you get from Thesis that set it apart and above most of its competition, are really very special.

Firstly, of course, you get the personalization mentioned above. This can be fantastic. Or it can be a little superfluous.

If you try something like NooCube, you will probably find it working for you. It may not be 100% scientifically optimal, but it will be 95% there for most of us.

However, if others haven’t worked for you, personalization may be a very good idea. You can really zero in on the aspects of your own cognitive health and function that you feel need improving.

Also, if you want to get that final 5% (figures not accurate, of course) and don’t mind parting with a little extra cash, Thesis can be well worth it. You will be as cognitively optimal as modern nootropic research can make you, which is no small thing.

Then there is the access to their experts . Again, this can be superfluous. How much do most of us really need to know about nootropics above and beyond what you can read in any good review or rundown? Just learn the basics, throw back a couple of NooCube capsules, and get on with your life.

But, again, it can be wonderful. This is where the extra price begins to seem really quite minimal.

Our Preferred Alternative To Thesis

Although we found Thesis Nootropics to include high-quality ingredients, the personalization for most people is not required and adds a lot of expense to an already pricey supplement.

We prefer NooCube, the nootropic taken by our tester and writer – thanks to its high-quality formula, high-impact results, and value for money cost.

Thesis Nootropic Ingredients

Thesis Nootropics offer several different blends, relatively personalized towards the individual, focused entirely on aiding different facets of cognition and brain health.

Given these differences, it’s no surprise that each blend contains a different list of ingredients – though there are of course some commonalities between them.

The Energy blend is one of their most popular. The formula is made to boost your energy levels whilst fighting fatigue and improving your mental stamina.

Next up, we have Thesis’ Clarity , which contains plenty of the ingredients I would expect to see in any good nootropic to maintain focus, support attention, and enter flow state – which is when you are achieving an optimal state of consciousness, fully immersed in a task and performing at your best.

Motivation is a bit of a funny one, as motivation is inherently a hard metric to either properly define or measure. However, in this context, motivation means a boost to willpower and productivity, and help in warding off procrastination.

Then we have Creativity , which is often misunderstood in nootropics. Being creative helps us think outside the box; stretch the imagination and come up with solutions to problems. This formula also works to improve verbal fluency and confidence. So what sounds like fandango initially could actually be incredibly beneficial on a day-to-day basis.

Finally, we have Thesis’ latest blend, Confidence . As you may well imagine, this leads to a boost in confidence!

Confidence’s ingredients all target stress, especially stress responses to insecurities, whilst promoting a feeling of self-assurance. It also aims to ‘soothe the nerves’, so that you can function calmly.

Edit: Thesis have since added Logic to their collection: perhaps their most closely linked to a classic nootropic, as it works to support memory, encourage deep thinking, and improve processing speed.

Ingredient Profiles

• Lion’s Mane Mushroom
• Camellia Sinensis Tea Leaf
• Dihydroxyflavone
• Agmatine Sulfate
• Panax Ginseng
• Ashwagandha Root
• Sceletium Tortuosum
• Ginkgo Biloba
• Theobromine
• Phosphatidylserine
• High DHA Algae
• Uridine Monophosphate
• Bacopa Monnieri
• N-Acetyl Cysteine
• Indian Trumpet Tree
• N-Acetyl L-Tyrosine
• L-Phenylalanine
• Methylliberine
• Vitamin B12
• Magnesium Bisglycinate
• Magnolia Bark
• Ashwagandha Leaf & Root

How to Use Thesis Nootropics

Nootropics are amongst the easier supplements to live with. There are no special timings or anything like that to hit, and the portions are all very manageable.

Thesis Nootropics fit this pattern nicely. For all of their different lines, simply take them in the morning, ideally when you first get up, on an empty stomach with a decent glass of water.

If you need a bit of an extra boost during the day (particularly if you’re going for the energy blend), feel free to take a second dose at lunchtime to see you through until the evening. This will ensure clarity and energy all day long.

Using Thesis Nootropics

I was quite sceptical of nootropics when I first heard about them in the early 2010s. They sounded too good to be true – over-the-counter supplements made from all-natural ingredients that can boost your brain health and cognitive function? No way.

Many are too good to be true. Plenty of nootropics out there don’t do anything above and beyond giving you a brief energy kick, and this is usually down to their caffeine content. You’d be better off having a cup of coffee or cheap caffeine supplement.

Thesis Nootropics are not too good to be true. They are good – very good, in fact – and highly workable.

I’m not entirely sold on them. I find them to be a bit gimmicky. They shouldn’t be gimmicky, of course – tailoring to your uses and offering coaching is no gimmick.

However, it’s just a little shallow to be truly tailored – they are simply giving you a selection of stacks, which many supplement stores offer (CrazyBulk, for instance).

And the coaching is perhaps a little superfluous for most people.

But the supplements themselves are good. They are well developed, well made, high quality, and will absolutely elicit the effects they claim in many, many people.

I got on well with them. I took their Energy blend first, which is always my priority (I’m always juggling seven or eight different projects at any time, so an energy boost will always be welcome!)

It did what it said it would. I found my focus improving and my energy lasting me through the day. I usually drink a lot of coffee, which tends to give me spikes and crashes. The spike wasn’t as high with the Energy blend, but nor was there any kind of crash.

I also tried Clarity, as I take a couple of prescription medications that can lead to a touch of brain fog. It cut through my brain fog well, lending me a great deal of clear-sighted cognitive energy. There was no coming round in the morning, no chugging espressos just to form a coherent sentence. Or, at least, I came round quicker and reduced my espresso intake.

I also wanted to know a bit about Thesis’ coaches, or whatever they call themselves.

I got in touch and was chatting to a woman with a highly relevant, impressive array of academic credentials just a few days later. She explained how the components in the blends I was trying worked and interplayed, and pointed me in the direction of a couple more that I might like to try.

The advice was kind of handy, though it wasn’t anything I would struggle to find out just from perusing their website. The information was interesting to a health and supplements nerd, but that was it. I can’t imagine it being in any way helpful. I can’t even imagine it being interesting to most people.

It’s not a good use of money (and you will be spending a lot of money on Thesis). The supplement is strong – the blends I tried were strong. But none of them gave me the kinds of results I have experienced whilst taking cheaper, better nootropics, namely NooCube – this is what I personally tend to take on an ongoing basis.

There is no harm in trying Thesis. They offer a one-month money-back guarantee, so you can get that hefty price tag (generally around $119) back again if you’re not satisfied.

I think you will be satisfied. Thesis is a satisfying product. It’s just not the best, and the best happens to be an awful lot cheaper.

Do also bear in mind that nootropics can cause side effects – Thesis’ blends are no exception. They can lead to blurred vision, high blood pressure, an accelerated pulse, circulation problems, and insomnia, though severe or long-lasting cases are rare.

Pros and Cons

Thesis pros.

• Personalized for optimal benefits.
• Comes with access to their experts.
• High-quality ingredients.
• Highly reputable company.
• Different blends for different uses/needs.
• Ability to try out different blends before committing.
• Easy to take.

Thesis Cons

• The personalization is a little shallow.
• It’s very pricey (about twice as costly as other leading nootropics).

Our Thesis Video Review

Thesis Nootropics are good. In fact, they are very good. The personalized aspect, whilst admittedly a little shallow, is still very welcome. I like it a lot.

As a bit of a supplements nerd, I also love the idea of being able to chat to an expert at any time – this really is a nice touch.

However, I can’t help but feel that it’s all a little superfluous. Most people know their own needs. A quick Google search will show you what nootropics will be best for you. If in doubt, go for a cover-all nootropic. I keep mentioning NooCube with good reason – it should do pretty much everything that all of Thesis’ blends do.

Then there is the price. You’re paying a lot for a good product with plenty of customer care involved. However, as above, the customer care is largely excessive. If you really want it – and I can see plenty of people wanting it, with good reason – then by all means fork out extra.

However, it’s just a little extravagant for most people.

For a month’s supply (at non-subscription prices), you can buy around three months’ worth of NooCube. For this, you’ll be getting just about the best nootropic on the market with no extra legwork – just simply take it each morning, save some money, and get on with your life with your cognitive health in near perfect shape.

Verdict: Thesis Nootropics

The reality is that most people won’t really gain from this additional 5%. Alternative products such as NooCube offer far greater value for money with similar (if not better) nootropic benefits.

This article was written by: James Dixon – SOMA Analytics PT, Nutritionalist & Published Author

James Dixon is one of the key players in the SOMA Analytics’ team. He is a personal trainer and is educated to Masters level. He is a published author and is a keen advocate of high quality nootropic supplements. James enjoys helping others to reach their peak both physically and mentally and believes that expressing his knowledge through his writing is an effective way to positively impact the wellbeing of others on a larger scale.

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Probable Nootropicinduced Psychiatric Adverse Effects: A Series of Four Cases

The misuse of nootropics—any substance that may alter, improve, or augment cognitive performance, mainly through the stimulation or inhibition of certain neurotransmitters—may potentially be dangerous and deleterious to the human brain, and certain individuals with a history of mental or substance use disorders might be particularly vulnerable to their adverse effects. We describe four cases of probable nootropic-induced psychiatric adverse effects to illustrate this theory. To the best of our knowledge this has not been previously reported in the formal medical literature. We briefly describe the most common classes of nootropics, including their postulated or proven methods of actions, their desired effects, and their adverse side effects, and provide a brief discussion of the cases. Our objective is to raise awareness among physicians in general and psychiatrists and addiction specialists in particular of the potentially dangerous phenomenon of unsupervised nootropic use among young adults who may be especially vulnerable to nootropics’ negative effects.

INTRODUCTION

Humans have historically sought to enhance and improve their mental and cognitive abilities. Chemically augmenting the human brain is the basis of nootropic brain enhancement—the development and experimentation with substances that can presumably improve cognition. A nootropic agent is any substance that may alter, improve, or augment cognitive performance, mainly through the stimulation or inhibition of certain neurotransmitters. 1 Nootropics have been shown to increase concentration and memory potential and potentiate cognitive functioning. 2 , 3 Nootropics include a wide range of substances, and the overall mechanisms of action for most nootropics have not been well elucidated. In this report, we describe the most commonly consumed and easily available nootropics. We also describe four cases of nootropic use that potentially led to unwanted serious adverse psychiatric effects. To the best of our knowledge this has not been previously reported in the formal medical literature.

COMMONLY USED NOOTROPICS

The overall evidence regarding the benefits of nootropics in healthy individuals seeking mental enhancement is still controversial. Additionally, it is important to note that nootropics are not free of adverse effects. Table 1 summarizes the mechanisms of action, desired neuropsychiatric effects, and adverse effects of the common classes of nootropics detailed below.

List of common nootropics, mode of action, desirable psychotropic effects, and adverse side effects

⇑: increase; GABA: gamma-amino butyric acid; AMPA: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

Armodafinil. Armodafinil, a wakefulness-promoting drug, is the R-isomer of racemic modafinil. Modafinil is a compound that produces an overall neuroexcitatory effect. The postulated mechanism of action is increasing the concentration of glutamate and decreasing gamma-amino butyric acid (GABA) within the posterior hypothalamus. 4 Armodafinil has been shown to improve wakefulness in patients with excessive sleepiness associated with treated obstructive sleep apnea and narcolepsy. Despite being the R-isomer of modafinil, armodafinil has a different pharmacokinetic profile and may result in improved wakefulness throughout the day compared with modafinil. 5

Adverse effects. Despite improving wakefulness, armodafinil’s adverse effects commonly include headache, nasopharyngitis, and diarrhea. 6

Citicoline. Citicoline, originally studied for its neuroprotective action against stroke and dementia, modulates acetylcholine, dopamine, and glutamate. It is also involved in phospholipid metabolism and enhances the integrity of neuronal membranes. 7 Citicoline has been shown to improve memory in patients with dementia as well as reduce damage to the brain after traumatic brain injury 8 or stroke. 9

Adverse effects. Citicoline has been found to cause gastrointestinal discomfort, headache, insomnia, myalgias, restlessness, fatigue, and tremors. 10

Piracetam. Piracetam, which is often used in early stages of Alzheimer’s disease and aging-related memory impairment, 11 is technically derived from GABA but is functionally unrelated to this neurotransmitter. It can act on the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor as an allosteric modulator binding in six different positions 12 and may have an effect on N-methyl- D-aspartate receptor (NMDA) and glutamate receptors. 13 Piracetam currently can be purchased online and is generally used for cognitive enhancement and memory improvement. 14 Piracetam has also been found to play a role in restoring membrane fluidity contributing to enhanced neuroplasticity 15 and neuroprotective effects. 16

Adverse effects. Piracetam users have reported symptoms of psychomotor agitation, dysphoria, tiredness, dizziness, memory loss, headache, and diarrhea. Many users reported to have neither felt any cognitive improvement nor psychedelic effects after taking piracetam. 17 - 19

Ampakines. Ampakines are a class of drugs that bind to the glutamatergic AMPA receptor, enhancing its activity 20 and potentially triggering the induction of long-term potentiation and improvement of learning, cognition, and alertness.

Adverse effects. Ampakines have also been found to cause headaches, somnolence, and nausea. 21 Despite the enhancement of long-term cortical neural potentiation with the use of ampakines, shifting cortical neural plasticity in favor of long-term potentiation could lead to impairments in spatial memory and perhaps motor function. 22

Cerebrolysin. Cerebrolysin, a mixture of low-molecular-weight peptides and amino acids derived from porcine brain tissue has been shown to have neuroprotective and neurotrophic properties by ameliorating sensory deficits and promoting synaptic formation and cholinergic fiber regeneration. 23 It is currently being used to treat ischemic strokes in China and Russia. 1 Cerebrolysin is reported to be safe when used in combination with recombinant tissue-type plasminogen activator or cholinesterase inhibitors such as donepezil or rivastigmine. 24

Adverse effects. Adverse reactions to cerebrolysin include vertigo, agitation, and feeling hot.

Accessibility. Nootropics are easily accessible via the internet through online vendors that appear as pharmacy websites frequently displaying images of physicians endorsing the products and promoting nootropic pharmaceutical products. 25 Nootropics, including those described above, can be ordered online without a medical prescription. 26 Nootropics are also widely available in most health and nutrition stores in many countries.

CASE REPORTS

Case 1. A 19-year-old male college student with a history of depression and attention deficit hyperactivity disorder (ADHD) presented to the emergency department with psychosis and paranoia resulting in self-injurious behavior. His current medication was bupropion, and historically he had been prescribed methylphenidate but was no longer taking that medication. His parents reported a history of cannabis abuse but he had been abstinent for the past year. No history of psychosis was reported. Previously, the patient was functioning well, in a euthymic state, and was attending his classes. He denied any substance abuse, and urine toxicology was negative. On further questioning, the patient revealed that he was taking a supplement to treat his ADHD. He reported purchasing it online. The supplement was found to be citicoline, and he had been consuming 2 to 3 tablets three times a day for several weeks. The family had noticed some insomnia and irritability early on, but no other concerning behaviors until now. The patient was admitted to the psychiatry department, and his symptoms resolved with olanzapine. He was discharged home in a stable condition and instructed to continue taking olanzapine for one month and to stop using all supplements.

Case 2. A 24-year-old male body builder with a history of anxiety presented to the emergency room with agitation and several days of hypomania. Currently, he was not on any medications, but previously had been treated with paroxetine for anxiety. Several years ago, he used anabolic steroids for a few months, but has not used them since. He reported smoking cannabis on weekends and consuming alcohol occasionally. Urine toxicology was negative. On questioning, he reported recently using cerebrolysin to enhance his cognitive performance, consuming two tablets twice daily. The supplement was obtained from a local health store. The patient received diazepam and was observed overnight. He improved significantly and was discharged home in stable condition. Diazepam was discontinued upon discharge from the hospital. He was instructed to stop all supplements.

Case 3. A 28-year-old female graduate student presented urgently to the psychiatry clinic for new onset insomnia, anxiety, and panic attacks. She reported a history of depression that was well controlled with psychotherapy. Currently, she was not taking any medications. She denied any illicit substance use and did not consume caffeine or smoke cigarettes. She admitted to being a casual cannabis smoker, but had not been using cannabis recently. The patient reported that she recently started using armodafinil to help her cope with her stressful academic program. Initially, she consumed armodafinil on an as-needed basis, and she felt improved performance and well-being. She then started using it regularly twice daily. Approximately one week later, the symptoms of insomnia, anxiety, and panic attacks began. The patient reported using armodafinil upon the suggestion of a friend, and it was obtained online from an overseas pharmacy. The patient was advised to stop armodafinil and was prescribed clonazepam twice daily until symptoms resolved one week later. At follow-up one week later, up her symptoms had resolved.

Case 4. A 17-year-old male high school student with obsessive compulsive disorder (OCD) and learning disabilities was admitted to the emergency room and then to the psychiatry department for exacerbation of OCD with akathesia and paranoia. He had previously been maintained on fluoxetine with good control of his OCD. He reported no substance abuse or caffeine use, which was confirmed by his parents. Urine toxicology was negative. No history of psychosis or paranoia was reported by the patient or his parents. Basic medical screening showed no abnormalities. On further questioning his parents reported that he had recently started using a supplement for memory. Further investigation revealed that the supplement was piracetam. The parents had not objected to him using the supplement since they perceived it as a safe and “natural remedy.” The supplements were obtained online. His symptoms improved with daily alprazolam and olanzapine at bedtime. Fluoxetine was discontinued. He was discharged home after a short hospital stay in a stable condition on olanzapine at bedtime. Piracetam was discontinued.

In addition to being young adults, all four of the described cases had some type of psychiatric history. Three of the four cases had a history of substance use, mainly cannabis. All of our cases reported an interest in maintaining a healthy and natural lifestyle. They did not perceive nootropics as harmful, voiced interest in “natural remedies,” and reported preferring to use supplements instead of prescription medications. They seemed not to be interested in experiencing euphoria or a pleasurable sensation, but rather to enhance their psychological or cognitive states. All cases improved rapidly and uneventfully with symptomatic treatment and discontinuation of the nootropics.

In our opinion, it is highly likely that nootropics were responsible for the psychiatric exacerbation in these cases, primarily, since they had been stable at their respective psychiatric baselines with no new psychosocial stressors or medication changes, except the initiation of nootropics. Additionally, there was no active or recent substance abuse. There is also a temporal correlation between initiating nootropics use and the psychiatric exacerbations reported.

Limitations. Two of the cases were taking psychotropic medications, which may have had drug interactions with the nootropics, causing the adverse effects. There is also the possibility of undisclosed or undetected substance abuse as a causal factor. A major limitation is the inability to definitely determine the actual composition of the nootropics, the dosing, and the frequency of use.

Healthcare providers in general, and specifically those in the mental health and substance abuse fields, should keep in mind that nootropic use is an under recognized and evolving problem. Nootropic use should be considered in cases where there are sudden or unexplained exacerbations of psychiatric symptoms in patients who have been stable and medication adherent. It is also important to remember that most nootropics are not detected on standard drug toxicology screening tests. We have very little clinical information on how nootropics may interact with psychotropics (or other medications) and potentially cause adverse physical and psychiatric side effects. Finally, because nootropics are often obtained via loosely regulated sources, such as online vendors, it is possible that other psychoactive compounds are substituted for the advertised nootropics. Young adults, especially those with a history of mental health or substance use disorders, may be at particular risk of adverse effects from use of nootropics and should be educated about the potential for harm from misuse of nootropics.

FUNDING: No funding was received for the preparation of this manuscript.

FINANCIAL DISCLOSURES: The authors have no conflicts of interest relevant to the content of this article.

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What Are Nootropics? Brain-Boosters Types, Benefits, And Side Effects

Nootropics, often referred to as "smart drugs" or cognitive enhancers, encompass a diverse range of natural compounds, synthetic substances, and pharmaceutical drugs..

Want to experience a limitless life with nootropics? Imagine an experience in which your mental clarity is razor-sharp, focus is unwavering, and energy is boundless. An experience in which cognitive limitations are shattered and your brain operates at its peak, day in and day out. This is where nootropics come in. But what are nootropics? Are nootropics safe? What are they made of and how do they work? From understanding what these products are to exploring their potential benefits, types, and safety considerations, this review guide is your compass to navigate the exciting area of cognitive optimization.

What Is Nootropic? Is It Safe?

Nootropics, often referred to as “smart drugs” or cognitive enhancers, encompass a diverse range of natural compounds, synthetic substances, and pharmaceutical drugs. Their shared goal is to enhance cognitive functions without causing significant side effects or addiction [1].

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The concept of nootropics was first introduced by Romanian psychologist and chemist Corneliu E. Giurgea in the 1970s. He defined nootropics as substances that exhibit the following characteristics [2]:

●     enhancement of learning and memory: Nootropics should enhance the brain's ability to learn, process, and retain information effectively;

●     neuroprotection: These compounds should protect the brain from harmful factors, such as oxidative stress and neurodegeneration;

●     enhanced cognitive function in normal brains: Nootropics should improve cognitive abilities in individuals with normal brain function, not just those with mental impairments;

●     safety: Nootropics should have minimal side effects and a low potential for toxicity or addiction.

The safety of cognitive enhancers varies depending on the specific compound, dosage, and individual factors. Many of the substances are generally considered safe when used as directed. Before using any nootropic, conduct thorough research on it and explore its mechanism of action, benefits, and potential side effects.

Also, you may wonder, do nootropics help with ADHD (attention deficit hyperactivity disorder) or any other medical condition? Yes, some types of “smart drugs” can help alleviate the symptoms of certain health problems. However, we'll return to this issue in the section below.

5 Benefits of Nootropic Supplements

Nootropic supplements offer a range of cognitive benefits that can enhance various aspects of mental function and overall well-being. While the effects can vary depending on the specific compound and individual factors, here are five key benefits most nootropics share [3][4]:

●     enhanced focus and concentration: Some brain boosters are good for improving focus and concentration. They can help reduce distractions and enhance your ability to stay engaged with tasks, leading to increased productivity and improved work performance & studying;

●     improved memory and learning: Several nootropics enhance memory retention and learning capabilities. They promote the formation of new neural connections, making it easier to acquire and retain new information;

●     increased mental clarity: Nootropics can contribute to mental clarity by reducing brain fog and enhancing cognitive processing. This can lead to clearer thinking, better decision-making, and improved problem-solving skills;

●     enhanced mood and motivation: Certain nootropics have mood-boosting properties that can help alleviate feelings of anxiety and stress. Additionally, they can promote motivation and a positive outlook, helping you approach tasks with enthusiasm and determination;

●     support for brain health and longevity: Some nootropics have neuroprotective effects, meaning they help safeguard brain cells from damage and degeneration. This can potentially contribute to long-term brain health and a reduced risk of cognitive decline as you age.

Additionally, the effects of nootropics may be more pronounced when combined with a healthy lifestyle that includes proper nutrition, regular exercise, sufficient sleep, and stress management.

Types of Nootropics

Nootropics can be broadly categorized into prescription drugs (or synthetic nootropics) and over-the-counter supplements, each with unique characteristics and potential benefits. Let's delve into each category of nootropics [5].

Prescription Drugs

Prescription nootropics refer to medications designed to treat medical conditions like narcolepsy and fatigue.

Prescription drugs ( Image link )

Here are some examples of this brain booster type:

●     Adderall: An amphetamine-based drug is efficacious in managing the symptoms associated with ADHD, helping individuals improve focus, attention, and impulse control;

●     Axura: With memantine as its active ingredient, the medication serves as a treatment for cognitive impairment, particularly in Alzheimer's disease. It aims to regulate the glutamate neurotransmitter, which plays a role in memory and learning processes;

●     Provigil (modafinil): It is prescribed to manage sleep-related disorders such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder. This wakefulness-fostering agent targets certain brain chemicals to promote alertness and combat extreme daytime sleepiness;

●     Ritalin (methylphenidate): This stimulant medication is primarily prescribed to individuals with ADHD to manage their symptoms & enhance their cognitive functioning.

While these drugs serve specific therapeutic purposes, they are often used off-label to enhance cognitive function. Among these nootropics, modafinil stands as the most effective “smart drug,” which provides a powerful brain boost. Many celebrities including Joe Rogan, Tim Ferris, Kelli White, and Dave Asprey admitted that they have tried this med for cognitive enhancement and boosted productivity, which confirms its popularity.

Over-the-Counter Nootropics

Over-the-counter (OTC) nootropics offer individuals the chance to improve cognitive abilities without needing a prescription. These accessible options include natural supplements like ginkgo biloba for memory, caffeine and L-theanine for balanced focus, and Bacopa monnieri for anxiety reduction and enhanced memory. Adaptogenic herbs like Rhodiola rosea, omega-3 fatty acids, vitamin B supplements, and choline supplements are also popular choices.

Nootropics stacks like Qualia Mind, Mind Lab Pro, NooCube, Hunter Focus, Vyvamind, Performance Lab Mind, and Alpha Brain also fall into this category. These supplements incorporate a blend of ingredients, often including herbal extracts, vitamins, and other compounds, to improve cognitive function and promote overall brain health. Unlike prescription medications, these OTC options can be obtained without the need for a doctor's prescription.

Where to Buy Nootropics Without a Prescription Online?

If you are interested in where to buy nootropics, including modafinil, without the need for a prescription, ModafinilXL, Afinil, and BuyModafinilOnline are reputable online pharmacies that provide not only convenience and accessibility but also a diverse array of premium-quality products. Let's take a look at each of these vendors.

ModafinilXL

ModafinilXL (MXL) is a renowned online pharmacy that specializes in selling generic modafinil and armodafinil brands sourced from various certified Indian manufacturers. Beyond its extensive product range, it places a strong emphasis on customer satisfaction and safety. This platform ensures secure payment methods such as Bitcoin, which comes with a 20% discount.

The vendor offers both domestic shipping across the UK & US and international shipping services to various countries. Rest assured, the e-pharmacy continuously monitors all orders, and if your package encounters customs issues, it will reship it at no cost or provide a full refund.

The vendor offers a range of coupon codes so you can save on your modafinil purchases:

●     MXLIMITLESS for $35 off orders of $500 or more;

●     USD10 for $10 off sitewide with no minimum order amount;

●     N15USD for $15 off orders of $170 or more;

●     OFF20N for $20 off orders of $250 or more;

●     USD25N for $25 off orders of $360 or more;

●     30BUCKS for $30 off orders of $500 or more.

By offering discounts on bulk purchases and even a returning customer bonus, ModafinilXL provides care for its clients and an opportunity to save. It also offers free trial samples to newbies so that they can try its products and determine their efficacy and safety.

BuyModafinilOnline

BuyModafinilOnline.com (BMO) is a reputable modafinil vendor similar to MXL. It offers a wide range of affordable generic brands for sale. It provides global shipping, though it doesn't ship to certain countries listed on its website due to customs restrictions.

BuyModafinilOnline pharmacy ( Image link )

With a 100% money-back guarantee for shipping issues, BMO prioritizes customer satisfaction. Like MXL, it offers fast international shipping that is free on orders worth $130. It has the option for domestic delivery across the USA and UK, which takes a maximum of 4 days.

Here are several coupon codes offered by BMO for discounts on purchases:

●     BMO-WHATEVERYOUWANT10: a $10 discount on any order sitewide;

●     BMO-COUPONHUNTERREWARD: a $35 discount on combo packs when your purchase totals $750+;

●     BMO-HMM15USD: Spend over $170 and get $15 off your cart;

●     BMO-YEP20OFF: Orders exceeding $250 are eligible for a $20 discount;

●     BMO-WOW25USD: Spend over $360 and enjoy a $25 discount.

Returning customers receive 10 extra sublingual Modafil MD pills for free. Leave a review after your purchase and get extra 20 modafinil tabs. Notably, BMO's pride lies in its free trial sample pack containing modafinil and armodafinil pills, allowing customers to experience the quality of its nootropics firsthand.

As a legit vendor, Afinil.com operates similarly to BMO and MXL in terms of medication assortment and pricing. It aims to provide an exceptional shopping experience with swift international delivery. It offers incentives such as $30 and $25 discounts to those who leave a review after the purchase and returning customers, respectively. Further, you may take advantage of Afinil's coupon codes:

●     AF-WHATEVERYOUWANT10: A $10 deduction on your order across the entire site;

●     AF-COUPONHUNTERREWARD: Buy nootropics valued at $750+ from any category and get a $35 reduction on your order;

●     AF-HMM15USD: For orders over $170, enjoy a $15 discount on your total purchase;

●     AF-YEP20OFF: On orders reaching $250+, get a $20 discount on your total purchase;

●     AF-WOW25USD: For orders exceeding $360, get a $25 discount on your total purchase.

The Bitcoin discount (24% off) can be combined with exclusive coupon offers for added savings. Afinil also offers flexible payment methods, including e-Check, PayPal, credit cards (MasterCard, Visa), and crypto.

Side Effects of Nootropics

While many users experience cognitive benefits, some individuals may also experience side effects [6]. Prescription nootropics, such as Adderall & Ritalin, might cause sleep disturbances, irritability, headaches, and changes in appetite. Modafinil may cause anxiety, headache, nausea, and nervousness, while methylphenidate may cause headache, irritability, depression, anxiety or tension, insomnia, and loss of appetite. Working closely with a healthcare professional is essential when considering prescription nootropics to monitor and manage potential side effects.

Over-the-counter nootropic supplements are considered safe when taken as directed, but some users may experience mild side effects. These may include headaches, digestive problems, nervousness, and mild allergic reactions. Start with a low dosage to assess your tolerance and choose reputable brands with transparent ingredient lists. Consult a physician before use, especially if you have pre-existing health conditions or are taking other medications.

Keep in mind that individual responses to nootropics can vary widely. What works well for one person may cause adverse effects in another. Factors such as genetics, existing health conditions, and other medications taken can all affect how the body responds to these substances. In all cases, responsible use is the key.

In summary, the world of nootropics offers a pathway to improved cognitive function and mental wellness. From prescription drugs to OTC supplements and natural compounds, the options are vast and intriguing. Modafinil, in particular, stands out as a remarkable pharmaceutical nootropic known for its safety, affordability, efficacy, and minimal risk of side effects. Its accessibility through legitimate online platforms such as ModafinilXL, BuyModafinilOnline, and Afinil further extends its reach, making it a viable choice for those seeking cognitive enhancement. These reputable providers offer a number of benefits, including competitive prices, quality assurance, secure transactions, and reliable customer support. In addition, these online pharmacies are known for their fast shipping services, ensuring that you receive your nootropic orders in a short time.

1.    Nootropic. Retrieved: August 20, 2023. Wikipedia.org.

2.    Corneliu E. Giurgea. Retrieved: August 20, 2023. Wikipedia.org.

3.    What Are Nootropics? By Divya Jacob, Pharm. D. Medically reviewed by Pallavi Suyog Uttekar, MD. Published: December 17, 2021. Medicinenet.com.

4.    The 10 Best Nootropic Supplements to Boost Brain Power. By Helen West. Updated: March 20, 2023. Retrieved: August 20, 2023. Healthline.com.

5.    What Are Nootropics? By Kendra Cherry. Medically reviewed by Shaheen Lakhan. Updated: November 3, 2022. Retrieved: August 20, 2023. Verywellmind.com.

6.    What Are Nootropics? By Barbara Brody. Medically reviewed by Dan Brennan, MD. Published: July 18, 2022. Webmd.com.

Disclaimer: The opinions expressed within this article are the personal opinions of the author. NDTV is not responsible for the accuracy, completeness, suitability, or validity of any information on this article. All information is provided on an as-is basis. The information, facts or opinions appearing in the article do not reflect the views of NDTV and NDTV does not assume any responsibility or liability for the same.

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Our innovative Starter Kit allows you to experience multiple formulations, and determine what works best. Our process is complex because we’ve found that it yields the best results in the shortest amount of time.

If we could formulate one pill that would work for everyone, we would! Because the human brain is deeply complex, that is just not possible.

Depending on your genetics and experience with nootropics, the effects can be felt in as little as 30 minutes after taking each blend.

Nootropics have the most impact when taken on an empty stomach, just after waking from a normal night of rest.

Some people may need a few days of consecutive use to feel the effects of the nutrients.

Thesis is shipped from our headquarters in New York City, via First Class Mail through the USPS, and takes about 1-3 business days to arrive within the continental US. Orders will be shipped same-day whenever possible.

If you are in need of priority shipping, email us ([email protected]) as soon as your order is placed, and we will upgrade it for you!

30-Day Money Back Guarantee

Try Thesis risk-free for 30 days, or your money back on your first order.