An Update on the Diagnosis and Treatment of Leprosy
(PDF) Ocular Findings in Leprosy in the United States
41784390 LEPROSY Research Paper
(PDF) Leprosy: A clinical review
Leprosy Transcript final
COMMENTS
Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
Abstract. Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden.
Experiences of living with leprosy: A systematic review and qualitative
1. Introduction. Leprosy is a chronic, granulomatous disease caused by Mycobacterium leprae.Multidrug therapy (MDT) for leprosy has been a huge global success. [] However, if leprosy is left untreated or treatment is delayed, it can cause progressive and permanent damage to tissues and nerves, leading to skin sores, ulcerations, physical deformities, severe disfigurements, and disabilities. []
Leprosy (Hansen's disease): An Update and Review
Introduction. Leprosy (Hansen's disease) is caused by infection of susceptible individuals with acid-fast bacilli (AFB) of the Mycobacterium leprae complex ( M. leprae and M. lepromatosis ). These rod-shaped AFB were first described by Gerhard Hansen in 1873. 1 M. leprae are slow growing organisms that replicate preferentially in macrophages ...
Leprosy now: epidemiology, progress, challenges, and research gaps
Priorities for research in leprosy cover a wide range of areas, from basic science to health services. Further understanding is needed of the epidemiology, including transmission, the role of the armadillo, and relative contributions of transmission and reinfection to the overall disease burden, and of the pathogenesis of nerve damage.
Leprosy: A Review of Epidemiology, Clinical Diagnosis, and ...
Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden.
(PDF) Leprosy: A systematic review
3.2.10 Nervous lesion. Leprosy is a neurologic condition affecting the peripheral. ne rves, from dermal terminations to nerve trunks, as a. clinically mixed neuropathy; as a result, the sensitive ...
Reservoirs and transmission routes of leprosy; A systematic review
Author summary Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy bacilli cause similar stigmatizing pathologic conditions. M. leprae primarily targets the skin and the peripheral nervous system. Currently it is considered a Neglected Tropical Disease. The transmission ...
Leprosy: diagnostic and control challenges for a worldwide disease
Leprosy is a curable disease with well-defined etiology, but lacks better diagnostic tools, preventive and therapeutic strategies. The continued application of the Ridley-Jopling clinical classification that recognizes the natural diversity of the immune response has provided the basis for understanding leprosy, and this review proposes its implementation in all Reference Centers in order to ...
Reservoirs and transmission routes of leprosy; A systematic review
A systematic review was conducted targeting leprosy transmission research data, using PubMed and Scopus as sources. Publications between January 1, 1945 and July 1, 2019 were included. The transmission pathways of M. leprae are not fully understood. Solid evidence exists of an increased risk for individuals living in close contact with leprosy ...
A comprehensive research agenda for zero leprosy
Similar to many other NTDs, leprosy is a complex condition in terms of its clinical and epidemiological characteristics, long-term medical and biological consequences (or effects), and intersections with socio-economic and cultural factors [10, 11].Several cross-cutting themes emerged during the working group and subgroup deliberations, including the need for integration between research efforts.
PDF Guidelines for the Diagnosis, Treatment and Prevention of Leprosy
IDRI Infectious Disease Research Institute ILEP International Federation of Anti-Leprosy Associations LPEP Leprosy Post-Exposure Prophylaxis LRI Leprosy Research Initiative ... Wood Memorial Center for Tuberculosis and Leprosy Research, the Philippines; Dr Wim H. van Brakel, Netherlands Leprosy Relief, the Netherlands; Mrs Paula Soares Brandao, ...
Leprosy: A Review of History, Clinical Presentation and Treatments
Abstract Leprosy is an ancient disease of mankind that has persisted for generations across various continents. The disease is caused by Mycobacterium leprae and Mycobacterium lepromatosis with ...
Experiences of living with leprosy: A systematic review and ...
Author summary Leprosy is a chronic, granulomatous disease caused by Mycobacterium leprae and is a major cause of preventable disability. As a result of their disfigurements and deteriorating physical impairments, the leprosy-affected individuals experienced negative social attitudes, stigma, isolation, and discrimination, thus, impacting their lives and relationships with others. Due to the ...
Leprosy: A Review of Epidemiology, Clinical Diagnosis, and Management
1. Introduction. Leprosy, or Hansen's disease, is a chronic bacterial infection caused by Mycobacterium leprae (M. leprae) infection []. M. leprae, the taxonomic order Actinomycetales, family Mycobacteriaceae, is an acid-fast, gram-positive obligate intracellular bacillus that demonstrates tropism for phagocytes in the skin and Schwann cells within peripheral nerves [].
Leprosy: Treatment and management of complications
In the second article in this continuing medical education series, we review the treatment of leprosy, its immunologic reactions, and important concepts, including disease relapse and drug resistance. A fundamental understanding of the treatment options and management of neuropathic sequelae are essential to reduce disease burden and improve patients' quality of life.
Unsolved matters in leprosy: a descriptive review and call for further
Leprosy, a chronic mycobacterial infection caused by Mycobacterium leprae, is an infectious disease that has ravaged human societies throughout millennia. This ancestral pathogen causes disfiguring cutaneous lesions, peripheral nerve injury, ostearticular deformity, limb loss and dysfunction, blindness and stigma. Despite ongoing efforts in interrupting leprosy transmission, large numbers of ...
A Bibliometric Analysis of Leprosy during 2000-2021 from Web of Science
The "leprosy review" published the most significant number of papers on leprosy, followed by "Plos Neglected Tropical Disease" and "International Journal of Leprosy and Other Mycobacterial Diseases." (2) Leprosy-related research was contributed to by 24,672 authors, and the ten authors with the most significant number of ...
(PDF) Leprosy: An Overview of Pathophysiology
Leprosy is a chronic and highly stigmatized, infectious disease caused by Mycobacterium leprae, a slow-growing, intracellular, non-cultivable mycobacterium [1] [2] [3]. In 1873, G. A. Hansen, a ...
PDF Leprosy: A Comprehensive Review of Epidemiology, Diagnosis, and Public
International Journal of Science and Research (IJSR) ISSN: 2319-7064 SJIF (2022): 7.942 . Volume 13 Issue 6, June 2024 . www.ijsr.net • and • • • • •
Interventions to reduce leprosy related stigma: A systematic review
Introduction. Leprosy stigma is a form of social stigma against those perceived to be affected by leprosy. Stigma is as old as the disease itself, with writings that date back to 2000 BC reporting on perceptions about those affected to be unclean, untrustworthy, and morally corrupt [1, 2].More formal segregation and the formation of "leper colonies" became mainstream in 12th century Europe ...
Probable Zoonotic Leprosy in the Southern United States
Leprosy (Hansen's disease) is a chronic infectious disease caused by Mycobacterium leprae. 1,2 Though often considered a disease of antiquity, it is found most commonly today in tropical and ...
(PDF) Diagnosis and Management of Leprosy
Abstract and Figures. Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which tends to attack peripheral nerves and skin. The diagnosis of leprosy is based on the ...
Leprosy in the 21st Century
She is the author of An Uncertain Cure: Living with Leprosy in Brazil (Rutgers University Press, 2009) and several peer-reviewed articles about Hansen's disease in the United States and Brazil. Her current research focus is on the experience of Hansen's disease and treatment seeking for first-generation Brazilian immigrants to the United States
Researchers discover DNA mechanism that regulates how disease-causing
The research paper has been published in Cell Metabolism. University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.
Delayed detection of leprosy cases: A systematic review of healthcare
In contrast, disruptions of decentralized leprosy care, such as a high turnover of health staff and low commitment, contributed to longer case-detection intervals , as reported in one study in Brasil (2020) that aimed to analyze assistance provided to people affected leprosy by healthcare management. One paper reported that, in Nepal, the ...
IMAGES
COMMENTS
Abstract. Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden.
1. Introduction. Leprosy is a chronic, granulomatous disease caused by Mycobacterium leprae.Multidrug therapy (MDT) for leprosy has been a huge global success. [] However, if leprosy is left untreated or treatment is delayed, it can cause progressive and permanent damage to tissues and nerves, leading to skin sores, ulcerations, physical deformities, severe disfigurements, and disabilities. []
Introduction. Leprosy (Hansen's disease) is caused by infection of susceptible individuals with acid-fast bacilli (AFB) of the Mycobacterium leprae complex ( M. leprae and M. lepromatosis ). These rod-shaped AFB were first described by Gerhard Hansen in 1873. 1 M. leprae are slow growing organisms that replicate preferentially in macrophages ...
Priorities for research in leprosy cover a wide range of areas, from basic science to health services. Further understanding is needed of the epidemiology, including transmission, the role of the armadillo, and relative contributions of transmission and reinfection to the overall disease burden, and of the pathogenesis of nerve damage.
Leprosy is a neglected infectious disease caused by acid-fast bacillus Mycobacterium leprae. It primarily affects the skin and then progresses to a secondary stage, causing peripheral neuropathy with potential long-term disability along with stigma. Leprosy patients account for a significant proportion of the global disease burden.
3.2.10 Nervous lesion. Leprosy is a neurologic condition affecting the peripheral. ne rves, from dermal terminations to nerve trunks, as a. clinically mixed neuropathy; as a result, the sensitive ...
Author summary Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy bacilli cause similar stigmatizing pathologic conditions. M. leprae primarily targets the skin and the peripheral nervous system. Currently it is considered a Neglected Tropical Disease. The transmission ...
Leprosy is a curable disease with well-defined etiology, but lacks better diagnostic tools, preventive and therapeutic strategies. The continued application of the Ridley-Jopling clinical classification that recognizes the natural diversity of the immune response has provided the basis for understanding leprosy, and this review proposes its implementation in all Reference Centers in order to ...
A systematic review was conducted targeting leprosy transmission research data, using PubMed and Scopus as sources. Publications between January 1, 1945 and July 1, 2019 were included. The transmission pathways of M. leprae are not fully understood. Solid evidence exists of an increased risk for individuals living in close contact with leprosy ...
Similar to many other NTDs, leprosy is a complex condition in terms of its clinical and epidemiological characteristics, long-term medical and biological consequences (or effects), and intersections with socio-economic and cultural factors [10, 11].Several cross-cutting themes emerged during the working group and subgroup deliberations, including the need for integration between research efforts.
IDRI Infectious Disease Research Institute ILEP International Federation of Anti-Leprosy Associations LPEP Leprosy Post-Exposure Prophylaxis LRI Leprosy Research Initiative ... Wood Memorial Center for Tuberculosis and Leprosy Research, the Philippines; Dr Wim H. van Brakel, Netherlands Leprosy Relief, the Netherlands; Mrs Paula Soares Brandao, ...
Abstract Leprosy is an ancient disease of mankind that has persisted for generations across various continents. The disease is caused by Mycobacterium leprae and Mycobacterium lepromatosis with ...
Author summary Leprosy is a chronic, granulomatous disease caused by Mycobacterium leprae and is a major cause of preventable disability. As a result of their disfigurements and deteriorating physical impairments, the leprosy-affected individuals experienced negative social attitudes, stigma, isolation, and discrimination, thus, impacting their lives and relationships with others. Due to the ...
1. Introduction. Leprosy, or Hansen's disease, is a chronic bacterial infection caused by Mycobacterium leprae (M. leprae) infection []. M. leprae, the taxonomic order Actinomycetales, family Mycobacteriaceae, is an acid-fast, gram-positive obligate intracellular bacillus that demonstrates tropism for phagocytes in the skin and Schwann cells within peripheral nerves [].
In the second article in this continuing medical education series, we review the treatment of leprosy, its immunologic reactions, and important concepts, including disease relapse and drug resistance. A fundamental understanding of the treatment options and management of neuropathic sequelae are essential to reduce disease burden and improve patients' quality of life.
Leprosy, a chronic mycobacterial infection caused by Mycobacterium leprae, is an infectious disease that has ravaged human societies throughout millennia. This ancestral pathogen causes disfiguring cutaneous lesions, peripheral nerve injury, ostearticular deformity, limb loss and dysfunction, blindness and stigma. Despite ongoing efforts in interrupting leprosy transmission, large numbers of ...
The "leprosy review" published the most significant number of papers on leprosy, followed by "Plos Neglected Tropical Disease" and "International Journal of Leprosy and Other Mycobacterial Diseases." (2) Leprosy-related research was contributed to by 24,672 authors, and the ten authors with the most significant number of ...
Leprosy is a chronic and highly stigmatized, infectious disease caused by Mycobacterium leprae, a slow-growing, intracellular, non-cultivable mycobacterium [1] [2] [3]. In 1873, G. A. Hansen, a ...
International Journal of Science and Research (IJSR) ISSN: 2319-7064 SJIF (2022): 7.942 . Volume 13 Issue 6, June 2024 . www.ijsr.net • and • • • • •
Introduction. Leprosy stigma is a form of social stigma against those perceived to be affected by leprosy. Stigma is as old as the disease itself, with writings that date back to 2000 BC reporting on perceptions about those affected to be unclean, untrustworthy, and morally corrupt [1, 2].More formal segregation and the formation of "leper colonies" became mainstream in 12th century Europe ...
Leprosy (Hansen's disease) is a chronic infectious disease caused by Mycobacterium leprae. 1,2 Though often considered a disease of antiquity, it is found most commonly today in tropical and ...
Abstract and Figures. Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which tends to attack peripheral nerves and skin. The diagnosis of leprosy is based on the ...
She is the author of An Uncertain Cure: Living with Leprosy in Brazil (Rutgers University Press, 2009) and several peer-reviewed articles about Hansen's disease in the United States and Brazil. Her current research focus is on the experience of Hansen's disease and treatment seeking for first-generation Brazilian immigrants to the United States
The research paper has been published in Cell Metabolism. University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.
In contrast, disruptions of decentralized leprosy care, such as a high turnover of health staff and low commitment, contributed to longer case-detection intervals , as reported in one study in Brasil (2020) that aimed to analyze assistance provided to people affected leprosy by healthcare management. One paper reported that, in Nepal, the ...