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Question: A Bad Reaction: A Case Study in Immunology by James A. Hewlett Science and Technology Department Finger Lakes Community College,Canandaigua, New York Part I You have been awarded a grant in the amount of s1200. Your research team is to use this grant to cover the costs of examining the case histories of three patients. Your goal is to make a diagnosis from

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1. The difference between an allergen and antigen is that an antigen is any foreign substance which might or might not become allergen. But an allergen is always an antigen. Allergen usually induce an allergic response whereas an antigen is a foreign …

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A Bad Reaction

A Case Study in Immunology

By James A. Hewlett

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A Bad Reaction

This case involves the transfer of a food allergy to a patient who received a combined kidney and liver transplant from a donor who died as the result of an allergic reaction. In addition to learning about the various roles of immune cells, the physiology of anaphylaxis, and the function of antibodies in immune physiology, students explore concepts related to histocompatibilities, organ donation, and organ rejection. The case is appropriate for use in a course in human physiology, a combined course in human anatomy and physiology, or an introductory course in immunology.

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  • Understand the physiology related to the sensitization to an allergen.
  • Understand physiology related to the allergic response that is produced during a secondary exposure to an antigen that an immune system is sensitized to.
  • Learn the difference between immediate, subacute, or delayed hypersensitivity.
  • Know the symptoms of anaphylaxis and the systemic manifestations of an immediate hypersensitivity reaction.
  • Learn about the various classes of immunoglobulins and the role of IgE in an allergic response.
  • Understand the role of T and B cells in the specific immune response.
  • Understand how an allergen, helper T cells, B cells, IgE, and basophils interact during an allergic response.
  • Understand the role of HLA (MHC) in organ compatibility, donation, and rejection.
  • Understand the difference between antigen and allergen.

Allergic reaction; allergen; peanut allergy; anaphylaxis; antigen; antibody; major histocompatibility complex; MHC; human leukocyte antigen; HLA; immune response; organ donation; tissue donation; liver transplant; kidney transplant; organ rejection

  

Subject Headings

EDUCATIONAL LEVEL

Undergraduate lower division, Undergraduate upper division

TOPICAL AREAS

TYPE/METHODS

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COMMENTS

  1. A Bad Reaction A Case Study In Immunology Answer Key

    Case Studies in Immunology: Drug-Induced Serum Sickness Raif Geha,FRED Rosen,2010-01-01 This is a case study of a 12-year-old boy who received massive intravenous penicillin and ampicillin injections to treat pneumonia and developed a serum sickness reaction to the antibiotics.

  2. A bad reaction; a case study in immunology - Anatomy and ...

    Anatomy and Physiology 2 Summer 1 session A Bad Reaction: A Case Study in Immunology Part A 1. An antigen is a foreign substance, normally a protein that stimulates the formation of antibodies. An allergen is a specific antigen that causes reactions relating to allergies.

  3. Solved A Bad Reaction: A Case Study in Immunology Adapted ...

    A Bad Reaction: A Case Study in Immunology. National Center for Case Study Teaching in Science, University at Buffalo, State University of New York. Retrieved from: http://sciencecases.lib.buffalo.edu This directed case study is based on a report from the New England Journal of Medicine describing the transfer of a peanut allergy to the ...

  4. A Bad Reaction A Case Study In Immunology Answer Key

    Case Studies in Immunology: Drug-Induced Serum Sickness Raif Geha,FRED Rosen,2010-01-01 This is a case study of a 12-year-old boy who received massive intravenous penicillin and ampicillin injections to treat pneumonia and developed a serum sickness reaction to the antibiotics.

  5. Solved Physiology Case Study Group 4: A Bad Reaction: A ...

    Solution. Here’s how to approach this question. To identify and describe the immunological mechanism that led to the patient's death, start by explaining the role of the peanut allergen in triggering an allergic response and leading to anaphylactic shock. View the full answer. Previous question Next question. Transcribed image text:

  6. A Bad Reaction A Case Study In Immunology Answer Key - Kari ...

    Case Studies in Immunology: Drug-Induced Serum Sickness Raif Geha,FRED Rosen,2010-01-01 This is a case study of a 12-year-old boy who received massive intravenous penicillin and ampicillin injections to treat pneumonia and developed a serum sickness reaction to the antibiotics.

  7. Solved A Bad Reaction: A Case Study in Immunology by James ...

    Answered by. Biology expert. 1. The difference between an allergen and antigen is that an antigen is any foreign substance which might or might not become allergen. But an allergen is always an antigen. Allergen usually induce an allergic response whereas an antigen is a foreign … View the full answer. Previous question Next question.

  8. A Bad Reaction - NSTA

    Know the symptoms of anaphylaxis and the systemic manifestations of an immediate hypersensitivity reaction. Learn about the various classes of immunoglobulins and the role of IgE in an allergic response. Understand the role of T and B cells in the specific immune response.

  9. A Bad Reaction: A Case Study in Immunology - NSTA

    Peanuts are one of the most common causes of food allergy in the United States and Europe. Tey are also a leading cause of food-induced anaphylaxis and death, which usually follow inadvertent exposures. Allergy to peanuts is an IgE-mediated, mast-cell-dependent, immediate-hypersensitivity reaction.

  10. A Bad Reaction A Case Study In Immunology Answer Key - M ...

    A Bad Reaction A Case Study In Immunology Answer Key Finding a Path to Safety in Food Allergy 2017-05-27 National Academies of Sciences, Engineering, and Medicine Over the past 20 years, public concerns have grown in response to the